As is often the case for yeast, the ability to sequence and analyze whole genomes at very deep coverage has yielded broad insights
on eukaryotic genome evolution.
Not exact matches
Over eons, pieces of mitochondrial DNA have naturally inserted into
eukaryotic genomes; at birth, for example, humans have between 755 and 1,155 germline mitochondrial DNA inserts that have been passed
on through generations.
The EBP would focus
on the natural world, providing a better understanding of biodiversity by first sequencing in great detail the DNA of a member of each
eukaryotic family (about 9000 in all) and eventually generating coarser
genomes for the other eukaryotes.
Our method, based ideally
on 20x and 50x of NaS and Illumina reads respectively, provides an efficient and cost - effective way of sequencing microbial or small
eukaryotic genomes in a very short time even in small facilities.
The team's work highlights this by presenting a comprehensive view of
genome evolution
on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other
eukaryotic organisms.