The Johns Hopkins Kimmel Cancer Center is one of 11 Lead Academic Organization sites of the National Cancer Institute's Experimental Therapeutics Clinical Trials Network (ETCTN), which supports the evaluation of early phase clinical trials
on experimental therapies.
Not exact matches
This biotech's first year as a publicly traded company has been a terrific ride
on the back of an
experimental oncology
therapy that could have huge built - in demand.
Among its top holdings, Intra-Cellular
Therapies (ITCI) was up more than 11 %, continuing a run that has helped the stock double in price since the end of August following positive data
on late - stage
experimental schizophrenia drug candidate ITI - 007.
On 13 April, the Texas Medical Board voted to accept rules intended to give doctors «a reasonable and responsible degree of latitude» in using
experimental stem cell
therapies.
And they would love for people in Sierra Leone, Guinea, and Liberia to have access to
experimental therapies as well, as the death toll from the largest Ebola outbreak
on record climbs past 600.
«We were surprised to find so many similarities between these two diseases, but most striking was that some of these common signatures are shared with other conditions like diabetic retinopathy and age - related macular degeneration,» said William A. Beltran, senior author
on the study, an associate professor of ophthalmology in Penn Vet's Department of Clinical Sciences and Advanced Medicine and director of the Division of
Experimental Retinal
Therapies.
Daniel Grinberg and Lluïsa Vilageliu, from the Department of Genetics of the Faculty of Biology, and Joan Blasi, from the Department of Pathology and
Experimental Therapy of the Faculty of Medicine, participated in the paper, published
on the journal Cell Reports.
Phase I studies focus
on questions related to the safety and best dose of
experimental therapies.
On 11 August, WHO convened a panel of medical ethicists, scientific experts, and lay people from the affected countries to assess the role of
experimental therapies in the Ebola outbreak response.
Cell
therapy, as envisaged by the teams of I - Stem, is primarily based
on the identification of
experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).
There are, however,
experimental therapies in development — and Charlie's parents have pinned their hopes
on one of them.
Specifically, they want their child to undergo nucleoside bypass
therapy, a treatment that Cohen called «highly
experimental» and which he noted would not work
on all mitochondrial diseases.
There are only a handful of approved treatments
on the market — most notably Merck's Keytruda and Opdivo — and most of the rest of the estimated 1,500
therapies are still in the
experimental stages.
The potential for cell
therapy to play a role in the
therapy of myelin disorders is under serious consideration, based
on years of experimentation of glial cell transplants in
experimental models.
Nucleoside bypass
therapy is highly
experimental and has never been used
on someone with Charlie's rare mitochondrial disease, but it has also shown promise in some cases.
Clinical research activities are focused
on the implementation of
experimental protocols based
on gene or cell
therapy for the treatment of genetic blood disorders such as ADA - SCID, Wiskott - Aldrich Syndrome, Metachromatic Leukodystrophy, Beta - thalassemia, Chronic granulomatous disease, Mucopolysaccharidosis Type I (Hurler).
University of Pennsylvania immunotherapy researcher Dr. Carl June, who led the development of an
experimental therapy for advanced childhood leukemia that is expected to become the first CAR T - cell therapy to win U.S. Food and Drug Administration approval, will give the keynote talk today at the Conference on Cell & Gene Therapy for HIV Cure at Fred Hutchinson Cancer Research
therapy for advanced childhood leukemia that is expected to become the first CAR T - cell
therapy to win U.S. Food and Drug Administration approval, will give the keynote talk today at the Conference on Cell & Gene Therapy for HIV Cure at Fred Hutchinson Cancer Research
therapy to win U.S. Food and Drug Administration approval, will give the keynote talk today at the Conference
on Cell & Gene
Therapy for HIV Cure at Fred Hutchinson Cancer Research
Therapy for HIV Cure at Fred Hutchinson Cancer Research Center.
At this time, any work
on gene
therapy is generally limited to
experimental work related to diseases that have no other cures.
On the other hand, sitting upright with good posture (spine in line, shoulders back) helped people with depressive symptoms feel more enthusiastic and less fatigued, found a recent study published in Journal of Behavior
Therapy and
Experimental Psychiatry.
On the plus side, the season introduced Meredith to the concept of
therapy; introduced a nurse, Rose [Lauren Stamile], who caught Derek's attention while he and Meredith were not together; the trials of the
experimental procedure for treating brain tumors, which served to keep Derek and Meredith in close proximity; the introduction of Dr. Erica Hahn [Brooke Smith]; the introduction of Meredith's half - sister, Lexie Grey [Chyler Leigh]; the crumbling of Bailey's [Chandra Wilson] marriage, and the possibility that Erica and Callie [Sara Ramirez] were lesbians.
We pursued chemo and a couple of
experimental therapies for Raven, as well as holistic alternatives, but
on Sept. 26, 2005, we lost her - only four months after the very first sign she was ill.
On this point, if the scientific evidence is inconclusive on the matter of a therapy's effectiveness, patients seeking these experimental treatments may be unable to tender compelling evidence that their physical pain is increased by the denial of coverage for that treatmen
On this point, if the scientific evidence is inconclusive
on the matter of a therapy's effectiveness, patients seeking these experimental treatments may be unable to tender compelling evidence that their physical pain is increased by the denial of coverage for that treatmen
on the matter of a
therapy's effectiveness, patients seeking these
experimental treatments may be unable to tender compelling evidence that their physical pain is increased by the denial of coverage for that treatment.
Behavior
therapy is considered probably efficacious for childhood depression, and a number of other
experimental interventions show promise but require further evaluation.12 Currently, only 2 research groups have focused
on psychosocial interventions for childhood bipolar disorder.13 - 15 Hence, increased attention to creation and testing of treatments specifically targeting depression and bipolar disorder in children is needed.16 In particular, studies should focus
on children's developmental needs, address comorbidity, involve family members in treatment, demonstrate treatment gains as rated by parents and clinicians rather than children themselves, and compare
experimental interventions with standard care or treatment as usual (TAU) rather than no - treatment or attention control groups.12, 17,18 In addition, parental psychopathology may affect treatment adherence and response.
Attachment
therapy has come under attack over the past five years or so because of
experimental therapies that have concentrated
on control of the child during
therapy, to the point of abuse and death.