The study, published by EcoHealth Alliance's Dr. Kevin Olival and Dr. David Hayman from Massey University, reviewed all of the current literature
on filoviruses — the class of viruses that include both Ebola and Marburg virus — and took a critical look at the ecological and virological methods needed to understand these viruses to protect human health.
Not exact matches
The largest outbreak
on record for the
filovirus family was caused by Ebola virus in West Africa between 2013 and 2016, resulting in more than 28,000 infections and more than 11,000 deaths.
Diagnostic reverse - transcription polymerase chain reaction kit for
filoviruses based
on the strain collections of all European biosafety level 4 laboratories
«The work
on antibodies isolated from survivors of
filovirus infections, including Marburg and Ebola, was started by James Crowe's laboratory at Vanderbilt University together with our laboratory about 3 years ago,» said virologist Alex Bukreyev, professor at UTMB and co-corresponding author.
Fedson says that many scientists who study
filoviruses like Ebola have yet to catch
on to the idea of treating the immune response.
The WHO
filovirus clinical working group, convened in response to the current outbreak, discussed the evidence
on convalescents» serum at a meeting in Geneva, Switzerland, at the end of July, says Bausch, who is part of the group.
They arrived at that estimate by showing that the Norway rat and the house mouse, which diverged from each other somewhere between 12 million and 24 million years ago, have the same
filovirus gene pieces integrated at the same places
on the same chromosomes.
Some reports based
on the estimated mutation rate of this virus family have suggested that
filoviruses are a mere 10,000 years old, but Derek Taylor, an evolutionary biologist at the State University of New York (SUNY), Buffalo, has found a new way to gauge their age.
The team is also working
on prevention of related Ebolavirus members Sudan virus (SUDV) and Bundibugyo virus (BDBV), and the related
filovirus Marburg virus.