Sentences with phrase «on gene activation»

Curcumin, a compound found in turmeric (Curcuma longa), can have multiple effects on gene activation, because it inhibits DNA methylation but also modulates histone acetylation.

Not exact matches

Additionally, turmeric has been shown to act on the liver to regulate epigenetic (activation of genes) and enzymatic factors that all work together to stabilize blood sugar and triglyceride levels in people with diabetes.

Researchers think it acts on another gene called lymphocyte activation gene - III, located at the other end of the same chromosome.

Yet, in this plant (as well as in certain conifers), the researchers found genes similar to those responsible for the formation of flowers, and which are organized according to the same hierarchy (with the activation of one gene activating the next gene, and so on)!

«In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on system allows activation of cellular genes.

Neurons, the functional units of our brain, develop through differentiation of neuronal precursors, a process that depends on coordinated activation of hundreds and possibly thousands of neuron - specific genes.

Another analysis focused on the patterns of gene activation during diapause, which the embryos of N. furzeri may undergo during the dry seasons.

The root fluoresces green when the TCSn gene associated with cytokinin activation is turned on because it is fused with a jellyfish protein that acts as a reporter signal.

Activation of NOTCH1 by blood flow causes a domino effect, triggering numerous other genes in the network to turn on or off, resulting in suppression of inflammation and calcification.

Kaufman and colleagues engineered the fish so that individual cells would light up in fluorescent green if a gene called crestin was turned on — a «beacon» indicating activation of a genetic program characteristic of stem cells.

According to the study, EWS / FLI binding and gene activation at promoter - like microsatellites is highly dependent on the length of GGAA motifs.

To demonstrate that CTCF binding is necessary for correct Hox gene activation, the researchers removed the sites on the genome where CTCF would normally bind and showed that without that CTCF binding, the Hox cluster would not fold properly.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

«The paper provides a dazzling snapshot of the process of transcription activation — the process whereby a gene is turned on in response to an instructive signal from the environment,» said Ann Hochschild, professor of microbiology and immunobiology at Harvard Medical School, who also was not part of the study.

The infection rapidly turned on a wide range of genes involved in immune system activation and cell death, they conclude, bolstering the hypothesis that the greatest harm may not have been done by the virus itself, but by an over-reactive immune system.

Originally, however, they were not examining brown fat thermogenesis, but instead were looking for clues to the function of ERRβ, a protein about which little was known at the time, except that it was closely related to ERRα, appeared in brown fat cells, and also worked as a so - called nuclear receptor — a molecular switch for gene activation that can be turned on by small lipophilic molecules or a signaling protein partner.

However it was not possible to determine whether these differences had contributed to the development of the disease, or if they live on as a memory of gene activation associated with the heart attack.

The activation of the oncogenes Cyclin E or Myc, on the other hand, induces the cells to begin replication of their DNA prematurely, without having had time to eliminate all the replication origins present in the genes.

He did post-doctoral work on genes regulating T cell activation, first with Harvey Cantor and then Lee Nadler at the Dana - Farber Cancer Institute.

A Harpin Binding Site in Tobacco Plasma Membranes Mediates Activation of the Pathogenesis - Related Gene HIN1 Independent of Extracellular Calcium but Dependent on Mitogen - Activated Protein Kinase Activity

His laboratory focuses on the roles of reversible protein modifications that are involved in modulating signal transduction, chromatin dynamics and gene activation.

Finally, pharmacological PPARα activation had a minimal effect on expression of cold - induced genes in murine WAT.

Stewart discovered that the histone modifications that poise embryonic stem cell - specific genes for activation are also found on the histones near genes involved in regeneration, putting them into a ready - to - go state.

Thus, the effects of SNCT clones on gene expression in endometrium observed after implantation are the result of delayed transcriptional activation arising from earlier communication with the conceptus and / or a direct effect of implantation.

The activation will depend on the type of cell the steroids are bind in and changes in how certain genes (especially genes that dominates during the puberty stage) will behave.

Reduce the inflammation, reduce the activation of your immune system, which is what turns on the genes.

Adults who had been categorized as behaviorally inhibited at the age of 2 years exhibited a higher amygdala activation in response to unknown vs familiar faces16 compared with adults who were uninhibited as children, consistent with the notion that novel or ambiguous environmental stimuli of potential biological relevance activate the amygdala.17 Turning to genes that can influence the neurobiological bases of the processing of emotions, 2 common alleles, the short (S) and the long (L), in a variable repeat sequence of the serotonin transporter (5 - HTT) promoter polymorphism (5 - HTTLPR) on human chromosome 17q11 have been differently associated with greater amygdala activity in response to angry or fearful faces18 in healthy adults.