Sentences with phrase «on genes responsible»

These NRF2 activators turn on the genes responsible for survival, and the protection within our cells against the damage and inflammation that age your dog and allow the expression of disease states.

The science suggests that by creating muscular tension you are switching on the genes responsible for synthesising new muscle and slowing the breakdown of existing muscle.

Not only do soft drinks contribute to disease, but they also shorten telomeres, which are the areas on our genes responsible for aging.

Nrf - 2 is a protein that works to regulate antioxidant gene induction, which turns on genes responsible for detox pathways.

When BMP turns ES cells into muscle it activates a protein called Smad1, a DNA - binding protein that, in opposition to Nanog, switches on genes responsible for muscle cell fate.

But in 1981 the east coast beckoned, in the form of an opportunity to work on the genes responsible for behaviour with Eric Kandel and Richard Axel at Columbia University — both of whom went on to win Nobel Prizes in 2000 and 2004 respectively.

In 1981, the east coast beckoned in the form of an opportunity to work on the genes responsible for behavior with Eric Kandel and Richard Axel at Columbia University — both of whom went on to win Nobel Prizes in 2000 and 2004, respectively.

To home in on the gene responsible, evolutionary biologists Chung - I Wu and Chau - Ti Ting at the University of Chicago inserted progressively shorter pieces of DNA from one species, Drosophila simulans, into a fly of another species, Drosophila mauritiana, and tested them for fertility.

Other researchers postulate that the muscle volumizing effect of creatine might switch on a gene responsible for IGF - 1 production.

Not exact matches

Scientists have figured out the specific gene mutation responsible for red hair — and why it's more common in beards than on heads.

Discovering the approximate location on the chromosome of the gene or genes responsible for a given disease will permit doctors to diagnose a genetic disease or predisposition before the onset of symptoms.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

Yet, in this plant (as well as in certain conifers), the researchers found genes similar to those responsible for the formation of flowers, and which are organized according to the same hierarchy (with the activation of one gene activating the next gene, and so on)!

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

Transcription factors are responsible for either inhibiting or promoting the expression of genes, and master regulatory transcription factors are like transcription factors on steroids: their actions regulate thousands of genes in different kinds of cells.

But the genetic factors underpinning seed coat permeability remained a mystery until Ma and his team used a map - based cloning approach to hone in on GmHs1 - 1 as the gene responsible for hard seededness.

The investigators» analyses demonstrated that XBP1 was responsible for turning on pro-atherogenic genes.

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

Alternatively, epigenetic changes — changes in the way genes are switched on and off — influencing key genes, induced by sex hormones, may be responsible.

In most cases, the genes responsible for these processes are known as «transcription factors» — meaning that they are responsible for turning other genes on and off.

There are two other genes, on different chromosomes, that code for different forms of the enzyme, and the team is now investigating whether mutations in these genes might be responsible for the other cases of ALS.

They have found a gene on chromosome 21 which they believe is responsible for many cases of the disease.

Dr. Wang said the team designed a sensor to glow (thanks to a firefly gene) when any compound activated the promoter DNA snippet responsible for turning on the c - MYC gene.

Compare that to the roughly 2 percent of the genome that is responsible for the protein - coding genes that researchers have been relying on to look for diseases and traits.

This was the reaction of Ron Worton, chief geneticist at the Hospital for Sick Children in Toronto, to the announcement on 24 August this year that his colleagues had cloned the gene responsible for cystic fibrosis — the CF gene.

Defective genes can be caused by mutations in either the maternally - inherited mitochondrial genome (mtDNA) or more frequently, the genes located on the autosomes, the 23 pairs of chromosomes which are responsible for all traits and all other genetic diseases.

For more than two decades we've known that a single gene on the Y chromosome, called Sry, is responsible for male sex determination.

In order for these unspecialized cells to acquire the characteristics that make a leaf cell different from a root cell or a blood cell different from a muscle cell, they must turn on different subsets of genes to produce the proteins responsible for each cell type's distinctive properties.

Engelhardt's group was responsible for mapping associations between genetic variants and gene expression levels on different chromosomes, a connection known as «trans - expression quantitative trait loci (trans - eQTLS).»

If we know which organs or tissues are most responsible for transporting copper throughout the body, we can focus on making sure the gene is expressed in those areas.

Over the years, her team has shown that it's responsible for 5 % of global photosynthesis and depends on an estimated 80,000 genes distributed among hundreds of strains to thrive in nutrient - poor waters ranging from the sea surface to 200 meters down.

Rather gene dosage, which depends on the number of chromosome copies, is responsible for this: «If the chromosome is multiplied, then more copies of the same gene will be transcribed.

These could alter the expression of genes on other chromosomes, and might be partly responsible for behavioural differences between the sexes, says Rissman.

«Responsible research on gene drives and gene drive technology requires consideration of values and public engagement throughout the process,» said committee co-chair Elizabeth Heitman, associate professor of medical ethics, Vanderbilt University Medical Center's Center for Biomedical Ethics and Society.

The researchers focused on 20 of the genes thought to be responsible for the lumbar cartilage matrix and found that one of them, called CILP, tends to be mutated in those with LDD.

Research had previously shown that eating honey turns on detoxification genes that metabolize the chemicals in honey, but the researchers wanted to identify the specific components responsible for this activity.

Cruse and Metcalfe looked at a gene called MS4A2, which is only expressed in mast cells and basophils, and is responsible for forming the IgE receptor on the mast cell.

The genes thought to be responsible for many of the pathologies associated with the disorder are being identified and mapped to sites on chromosome 21

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

UNSW Australia scientists have discovered a link between autism and genetic changes in some segments of DNA that are responsible for switching on genes in the brain.

Just because scientists know the gene responsible for a rare disease doesn't mean they know what's going on.

In this case, Zhijian «Jake» Tu and colleagues found that placing a particular Y chromosome gene on the autosomes of Anopheles stephensi mosquitoes — a species responsible for transmitting malaria — killed off 100 percent of all female embryos that inherited this gene.

In an earlier study, Wahl and his team discovered that Mdm2 and Mdmx cooperate to prevent p53 from being activated, with Mdm2 being primarily responsible for degrading p53, while Mdmx is more effective at preventing p53 from turning on genes.

Now that the question of which genes are responsible for which terpenes, Richter will move on to the study of how these genes are regulated.

Kathy Niakan and colleagues are providing new understanding of the genes responsible for a crucial change when groups of cells in the very early embryo first become organised and set on different paths of development.

And because finch populations in the Western United States and Hawaii were not affected by this bacterial outbreak, genetic comparison can help determine whether Mhc genes were responsible for protecting finch populations on the East Coast after the initial disaster in 1994.

Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the gene encoding the LCMV envelope protein, normally responsible for virus entry into target cells, has been deleted and replaced with a target gene of interest.

Furthermore, they identified one gene (DYRK1A) on human chromosome 21, whose overdose in trisomy (DS) is responsible for the observed effects.

Within RD - Connect's sister project Neuromics, Hanns was the disease coordinator for the congenital myasthenic syndromes, and in this and several other exome sequencing projects was responsible for gene discovery and work on disease modifying factors influencing severity of phenotype.

The results suggested that each of the Wnt genes (Wnt - 2b, Wnt - 8c, Wnt - 3a) were responsible for turning on two forms of FGF, each of which controls both limb initiation and a bud or bulge known as the apical ectodermal ridge (AER), which acts as the «organizer» of limb development.