Sentences with phrase «on gliosis»
Grn − / − mice were included in the study to test for progranulin - independent benefits of exercise on gliosis.
http://www.eneuro.org/ Not exact matches
Since the TMEM106B genetic variant on brain aging was also apparent in patients with Alzheimer's disease, Rhinn explained that «one interpretation is that TMEM106B is a critical element of a resilience network in the frontal cortex that limits the extent of neuronal loss and gliosis.»
We therefore included Grn − / − mice in the study to test the secondary hypothesis that exercise could improve gliosis independent of any effect on progranulin expression.
Although it was not the primary endpoint of our analyses, we took the opportunity to assess whether exercise, which is known to have anti-inflammatory effects, might reduce gliosis and inflammation in Grn − / − mice, which would be independent of an effect on progranulin levels.