He focused first
on haemophilia B. Adapting a technique that he had previously developed to delay the onset of type 1 diabetes, Daniell and his group genetically modified tobacco plants to express human factor IX in their chloroplasts.
Not exact matches
The man's brother was almost bedridden by
haemophilia, but the soldier's symptoms were so mild that he did not even realize that he had the disease until he was shot
on the battlefield.
Drug company Baxter International, based in Deerfield, Illinois, sells recombinant clotting factors for treating
haemophilia and also has its sights
on TFPI.
The test developed can be carried out
on mothers at risk of X-linked genetic recessive diseases including
haemophilia and Duchenne muscular dystrophy and mothers at risk of haemolytic disease of the new - born.
2011 Six people with clotting disorder
haemophilia B see a reduction in symptoms after gene therapy
on liver cells.
Depending
on the person, the amount of factor VIII — the protein missing in
haemophilia A — in the bloodstream drops by half in a mere 8 — 12 hours.
The hunt is
on for ways to diagnose and treat the joint problems that are now the main chronic problem in
haemophilia
Disorders like
haemophilia that are caused by faults
on the X chromosome are therefore more common in males.
Almost exactly a year ago, we reported
on a gene therapy for
haemophilia that was in development by the Children's Hospital of Philadelphia (and subsequently the CHOP spinout Spark Therapeutics).
Indeed, psychological interventions have been proven to be effective in a broad range of disorders and illnesses.15 — 18 Although a few former works have focused
on psychological interventions in
haemophilia, showing positive and promising results, 19 — 25 the lack of recent papers exploring this issue is somewhat surprising, despite the recommendations and guidelines that emphasise their relevance.