(Source) Another study examined the inhibitory effects of clove ethyl acetate extract
on human cancer cell lines.
Anti-proliferative action of endogenous dehydroepiandrosterone metabolites
on human cancer cell lines..
Not exact matches
«This model was trained
on genetic data from
human tumors in The
Cancer Genome Atlas and was able to predict response to certain inhibitors that affect cancers with overactive Ras signaling in an encyclopedia of cancer cell lines,» Greene
Cancer Genome Atlas and was able to predict response to certain inhibitors that affect
cancers with overactive Ras signaling in an encyclopedia of
cancer cell lines,» Greene
cancer cell lines,» Greene said.
The researchers observed the effect of the synthetically produced molecule, JK - 31,
on the growth and proliferation of a model
human breast
cancer cell line and found that it effectively blocked the protein cyclin - dependent kinase 1 (CDK1), which plays a key part in the process of the division of
cancer cells, and therefore inhibited the proliferation of the
cells.
To see whether
cancer stem
cell renewal involves a chain of events similar to that used by embryonic stem
cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies
on two
human breast
cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.
In addition to the afatinib - resistant NSCLC
cells, the researchers tested the neratinib and valproic acid combination
on cell lines derived from
human pancreatic and ovarian
cancers containing K - Ras mutations and N - Ras mutations, respectively.
The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple
human cancer cell lines to different chemotherapy agents based
on the
cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor
cells to common classes of chemotherapy treatment.
To test their hypothesis, the researchers carried out experiments
on human melanoma
cells, a
line of
cancer cells they chose for their ability to grow easily and quickly.
The researchers tested honokiol
on cell lines derived from
human cancers of the oral cavity, larynx, tongue, and pharynx.
But a computer game that puts those kids
on the front
line of a battlefield inside the
human body — where
cancer cells and chemotherapy drugs are slogging it out for supremacy — just might persuade them that it's important to keep taking the drugs.
To determine whether the reactivation of methylation - silenced genes by EGCG is a general phenomenon that also occurs in other
cell lines, we studied the effects of EGCG treatment
on the methylation status and mRNA levels of p16INK4a or RARβ in three other
human cancer cell lines (Fig. 3C) ⇓.
To study the effect of hypoxia / reoxygenation cycles
on breast
cancer, we exposed two metastatic
human breast
cancer cell lines (MDA - MB 231 and BCM2) to cycles of chronic hypoxia and nutrient deprivation.
canSAR contains information
on the entire
human proteome — the protein equivalent of the
human genome - as well as linking to information
on more than 1,000
cancer cells lines, used by researchers to study the effect of new drugs in the lab.
On the basis of studies on the XMRV - producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mic
On the basis of studies
on the XMRV - producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mic
on the XMRV - producing
human prostate
cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.