Sentences with phrase «on hypocretin»

Twenty years after the colony was established at Stanford University, linkage analysis identified the causative allele on the hypocretin receptor 2 (hcrtr2) gene [86].

Scientists hypothesized that the problem with S. pyogenes might be «molecular mimicry,» in which a molecular pattern on the bacterium resembles proteins on those hypocretin neurons.

Three groups independently studying people with narcolepsy identified antibodies against the same protein, tribble 2, that's found on hypocretin neurons.

They focused this effect on the hypocretin neurons, which are brain cells in the lateral hypothalamus.

Not exact matches

Using gene mapping techniques, the researchers zeroed in on a mutation in the gene for hypocretin receptor 2.

Think of brain cells as rooms with locks called receptors on their surfaces and a hypocretin as a key that is also a stimulant.

Relying on tests that used blood from Pandemrix recipients, the study authors showed it triggered antibodies that not only attack the virus but also bind to hypocretin receptors, potentially killing them.

Meanwhile, pharmaceutical companies are racing to design new narcolepsy drugs based on the discovery of hypocretin's central role in the disorder.

Experiments on mice show that re-feeding restores normal Hypocretin activity, to an extent.

Moreover, some recent complicated neurobiological work done on mice has shown that injecting them with leptin decreases the activity of their Hypocretin Neurons.

GABA neurons also create a bridge between Neuropeptite Y, which is the molecule that arguably has the strongest appetite - stimulating effect on the brain, and Hypocretin Neurons (more on Neuropeptide Y later this week).