The pathogenesis of this appears to be based
on an immunological reaction against the basic protein in myelin that is triggered by the distemper virus.
Instead of having to maintain high antibody levels against too many things, Nature relies
on immunological memory.
Abuse, belittlement, insults, neglect, loss of loved ones, parental acrimony... the traumas children weather unfortunately become a lifelong «operating system» that has profound influences
on immunological and neurological health.
The successful candidate will study how defined immune evasion functions encoded by CMV impact
on immunological control of virus, and the progression of disease.
The AADCRC program is the cornerstone of NIAID efforts to promote multidisciplinary basic and clinical research
on the immunological basis, pathobiology, diagnosis, treatment, and preven tion of asthma and allergic diseases.
Not exact matches
, antibacterial soaps... kids were kept in as sterile environment as possible... and along came asthma, allergies, skin sensitivities... a host of
immunological issues brought
on by the sterile environment that kept the children from building their natural immunities to the germs of the world.
Through continued study, breastmilk has been shown repeatedly to have a wide array of effectiveness against disease - causing agents and lead to an overall positive
immunological effect
on the health and well being of the infant and mother.
The authors are continuing their study of urban impacts
on finches — emphasizing the behavioral and
immunological impacts of humans and urban parasites
on the birds.
Thus, helminths may have important effects
on human fertility that reflect physiological and
immunological consequences of infection.
CIEP and similar
immunological methods «are based
on detecting proteins by using antibodies that would recognize the protein by shape.
«If we can decipher the local
immunological changes that give rise to the accumulation of one of the subgroups involved in these patchy skin disorders, we'll be
on the way to more targeted treatments,» says Dr Eidsmo.
Recent contributions have focused
on support and education programs for patients with cancer or with a diagnosed
immunological disorder.
The researchers developed an
immunological assay based
on floating gate transistors.
The European research collaboration behind this study focuses
on deep
immunological analysis of the immunogenicity and reactogenicity of the Ebola vaccine in healthy volunteers.
The study gathered information
on environmental, genetic, and
immunological factors collected from blood samples and questionnaires between 1996 and 2014.
The broad influence of the immune system
on diverse aspects of health and disease is beginning to be appreciated, and innovative
immunological interventions are proving successful in the clinic.
I went to a couple of history of science — I am very interested in history of science — there were some great sessions
on Marie Curie and
on the history of alchemy, and the hygiene hypothesis where you find that kids who are not exposed to enough of an
immunological challenge when they are in the womb or very young can have higher rates of asthma and autoimmune conditions; and also some stuff
on the Large Hadron Collider is going to be coming up.
The toxin triggers the body into mounting a massive
immunological attack
on itself.
The study is the first to provide
immunological evidence
on the role of gestational infection in autism, reporting an association between maternal anti-herpes simplex virus - 2 (HSV - 2) antibodies and risk for ASD in offspring.
«If you turn back
on an immune regulatory switch that the body has decided to turn off,» Walker cautions, «you could trigger serious
immunological problems.»
The CPC maintains a focus
on experimental pneumology with the investigation of cellular, molecular and
immunological mechanisms involved in lung diseases.
Arturo Casadevall, chair of the Department of Microbiology and Immunology and director of the Center for
Immunological Sciences at the Albert Einstein College of Medicine, who has been studying Cryptococcus for over 20 years, has compared the phenomenon with a card game where soil microbes are playing for survival, but by chance, a few hands confer «accidental virulence»
on other hosts.
Immunological Invisibility Cloak Among them is Joel Linden, Ph.D., who recently reported that jamming signals transmitted by membrane proteins called adenosine receptors, which are expressed
on T cells and
on specialized cell - killing cells called NK cells, made both cell types more effective in halting lung metastasis of melanoma cells.
We expect that the CRI iAtlas will help to accelerate discovery and improve patient outcomes by providing researchers greater access to genomics data to better understand the
immunological characteristics of the tumor microenvironment and its potential impact
on patient responses to immunotherapy,» said Jill O'Donnell - Tormey, Ph.D., CEO and director of scientific affairs at CRI.
With the iconic Australian marsupial carnivore
on the brink of extinction, Tasmanian researchers race to unlock the
immunological mysteries of a disease threatening the species.
Since they confer regulation
on the majority of human genes, it is not surprising that microRNAs are involved in numerous biological processes, including cardiovascular,
immunological, neurodegenerative, and psychiatric diseases and cancer.
The results were even more auspicious when the investigators stratified vaccinated subjects by antibody responder status: subjects who successfully mounted an
immunological response to the vaccine enjoyed statistically significant benefits as measured with the IGA, the two motor function subscales of the MDS - UPDRS, and the Parkinson's Disease Questionnaire (PDQ - 39) of quality of life (though not
on the PD Non-Motor Symptoms Questionnaire (NMS - Quest / PD - NMS)-RRB-, while no benefit was observed in nonresponders
on any scale (Table 1).
Career Plans: I plan
on going back to school to achieve either a Ph.D. or Masters and currently I'm interested in staying in an
immunological specialization.
His motivation to gain broad experience in several
immunological methods and to understand the vast
immunological scenarios, in combination with the deep expertise in T cell characterization is paving the road for him to chase a career in scientific research focused
on understanding and developing better strategies to efficiently tackle human diseases.
Currently, at the Ragon Institute of MGH, MIT & Harvard, she will be focus
on the study of different pharmaceutical and
immunological strategies to reduce HIV - 1 persistence.
Bernhard Mlecnik and coleagues examin the impact of tumor - intrinsic, microenvironmental, and
immunological factors
on tumor metastasis in colorectal cancer patients.
Career Goals: I plan to pursue a career in scientific research focusing
on the discovery of drug targets to improve the treatment options of human
immunological diseases and cancer.
I am currently involved in RNA sequencing for two projects focused
on transcriptome analysis of immune cells in various
immunological diseases and cancer.
Phenome — Since the first publication
on the BXDs, well over 200 research groups have generated behavioral, neurological, pharmacological,
immunological, and more recently, metabolic phenotypes for this family.
Our group focuses
on developing pharmaceutical and
immunological strategies to reduce HIV - 1 persistence, and
on evaluating such interventions in clinical studies.
Current studies focus mainly
on two receptor systems - the mast cell surface receptor, FcεRI, and the receptor for epidermal growth factor that operate in
immunological and cell proliferation responses.
Examples include a series of studies to document persistent microchimerism of donor cells in transfusion recipients, with particular focus
on mechanisms and clinical relevance of donor stem cell microchimerism in transfused trauma patients, and the
immunological mechanisms and prevention of transfusion - related acute lung injury (TRALI) and alloimmunization.
We suggest that
immunological choices are superimposed
on altered viral gene expression profiles to determine immunodominance during chronic murine CMV infection.
All requirements for high level
immunological determinations (including ELISPOT reader, FACSAria, LSRII system fully equipped, Luminex, multi-label plate reader) are
on site and in routine use.
Through the CIC program, the Cancer Research Institute conducts a number of important initiatives that seek among other things to build consensus across the field
on key issues, to develop and implement new standards for carrying out and reporting
immunological monitoring assays of therapeutic cancer vaccines, and to establish and promote the adoption of new criteria for evaluating the clinical impact of cancer immunotherapies.
1994 saw her as Head of the Department of Transplantation Immunology at the CLB, in Amsterdam, and in 1999 she became Head of the department of the Immunology of the Laboratory of Vaccine Research of the National Institute of Public Health and Environmental Protection (RIVM), in Bilthoven, where her research activities focused
on defining
immunological correlates of protection
on the T and B cell level after natural infection and vaccination.
Published studies have suggested that T1D results from environmental triggers acting
on genetically susceptible individuals and that microbial infection and their
immunological consequences are suspected to take part in the pathogenesis.
But breast milk is far from static — one of the most amazing properties of this maternal masterpiece is that it's incredibly dynamic, and it changes based
on your baby's unique developmental and
immunological needs.
«
Immunological genes are many and complex, and your immune response depends
on their combined performance,» Dr. Boffetta explains.
In fact in a recent study in 2016
on the «Strong Anti-inflammatory Effects of Curcumin» by Vetivicka and Vetivickova, demonstrated that only Curcumin C3 Complex had both anti-inflammatory and
immunological activity in comparison to four other brands of generic 95 percent curcuminoids in both vitro and vivo testing.
Her clinical work focuses
on functional nutrition, the microbiome, and the
immunological reactions involved in food allergy and intolerances.
These transmissions partly depend
on the health of the microbiome (or gut flora), so when the balance of gut bacteria isn't working right, other biological pathways including hormonal,
immunological or neuronal won't work right either.
It is not yet known if the condition results from an
immunological reaction similar to that seen in celiac disease, or whether gluten exerts a chemical or other negative effect
on digestion.
Without question, food sensitivities and allergic reactions to foods and food chemicals are
on the rise making diagnostic testing an important way to identify adverse
immunological responses to various foods and chemicals.
Dr. Cheng's research has been focused
on animal well - being, with emphases
on the interactions of the psychological, genetic, neurobiological, physiological, and
immunological events that alter an animal's adaptability to husbandry environments.