«We studied how the Sox2 gene is turned on in mice, and found the region of the genome that is needed to turn the gene
on in embryonic stem cells,» said Professor Jennifer Mitchell of U of T's Department of Cell and Systems Biology, lead invesigator of a study published in the December 15 issue of Genes & Development.
Mitchell and her colleagues eliminated this possibility when they deleted these nearby regions in the genome of mice and found there was no impact on the gene's ability to be turned
on in embryonic stem cells.
Not exact matches
If we are against the use of
stem cell research
on the basis of
embryonic destruction, shouldn't we also be against
in - vitro fertilization clinics because there are always excess embryos that get discarded?
research; since most of the reports have concentrated
on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases such as Parkinson's, «
stem -
cells» has become synonymous with «
embryonic stem -
cells»
in the public imagination.
In all likelihood, soon after he is sworn in, federal dollars will start flowing toward research on new embryonic stem - cell lines, bringing with it new battles to figh
In all likelihood, soon after he is sworn
in, federal dollars will start flowing toward research on new embryonic stem - cell lines, bringing with it new battles to figh
in, federal dollars will start flowing toward research
on new
embryonic stem -
cell lines, bringing with it new battles to fight.
Not surprisingly, President Obama received high marks from the journal, largely because his response to the question of whether he would lift Bush's ban
on the federal funding of new
embryonic stem -
cell lines is
in line with the view of most
in the scientific community.
In fact, when the 2007 paper came out, the commentaries in most scientific publications were quick to point out that, despite the success with adult cells, there was still a need to continue embryo - destructive research and that it would be critical to the advancement of science that research on embryonic stem cells continu
In fact, when the 2007 paper came out, the commentaries
in most scientific publications were quick to point out that, despite the success with adult cells, there was still a need to continue embryo - destructive research and that it would be critical to the advancement of science that research on embryonic stem cells continu
in most scientific publications were quick to point out that, despite the success with adult
cells, there was still a need to continue embryo - destructive research and that it would be critical to the advancement of science that research
on embryonic stem cells continue.
(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education for older school children; (ix) treating drug abuse as principally a medical issue; (x) population control; (xi) buying alcohol
on a Sunday
in many places; (xii) use of condoms and other contraceptives; (xiii)
embryonic stem cell research; (xiv) little 10 year - old boys joining organizations such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly
in the military.
Sullivan went
on to suggest that Chaput is using a double standard
in the 2008 election by criticizing Catholic supporters of Barack Obama, while turning a blind eye to John McCain's support for
embryonic stem cell research.
It has brought healing, conveniences, communications, and knowledge unimaginable
in earlier times, but
on the other hand it has brought advanced killing technology, pollution, and
embryonic stem cell research.
In August of last year, President Bush approved the use of federal funds to support research
on a limited number of existing human
embryonic stem cell lines.
But
on the same day, he also revoked the very kind of policy that promoted the «purple» governance he claimed to want, e.g., Bush's directive that funding priority be given to funding non
embryonic — and hence, societally uniting sources of pluripotent
stem cells — even though they had already been discovered
in the induced pluripotent
stem cell breakthrough.
Unfortunately, at this formative stage
in their lives one viewpoint is pushed to the fore
on campus, and that's the opinion that euthanasia, abortion,
embryonic stem cell research and a host of other practices which strip humans of their most fundamental right are good things.
The isolation of
embryonic stem cells by Dr. James Thomson
in 1998 put the issue of
stem cell research
on the map.
Geron was bigger and better funded than ACT, and it was the first company to be approved by the US Food and Drug Administration (FDA) to test a therapy
in humans based
on embryonic stem (ES)
cells.
In granting an injunction to two scientists who oppose widening US government funding for research
on human
embryonic stem cells (hESCs), Judge Royce Lamberth wrote of «simply preserving the status quo».
In March, advocate general Yves Bot issued a preliminary judgment limiting patents involving
embryonic stem cells,
on the basis that they «would be contrary to ethics and public policy» (see «European Court of Justice rejects
stem -
cell patents»).
In the United Kingdom, research on embryonic stem cells is legal in the first 2 weeks of their developmen
In the United Kingdom, research
on embryonic stem cells is legal
in the first 2 weeks of their developmen
in the first 2 weeks of their development.
The creation of the Centre of Regenerative Medicine
in Barcelona (CMRB) reflects «a change
in the Spanish public policy regarding derivation and use of human
embryonic stem cells (HESC), based
on a progressive evolution of the public awareness and sensibility of the Spanish [citizenry],» says CMRB Director Juan Carlos Izpisúa Belmonte
in an e-mail.
Researchers called them induced pluripotent
cells, which are created by enticing
cells to turn
on genes normally found
in embryonic stem cells.
Future research should not only compare how
embryonic stem cells, iPS
cells and adult
stem cells differentiate, but focus
on what effects the niche
in which these
cells will reside, when transplanted, will have
on their characteristics, including tendencies to mutate into cancer
cells, notes
cell and
stem cell biologist Olga Genbacev at the University of California, San Francisco, (U.C.S.F.) School of Medicine.
But just how close adult and reprogrammed
stem cells can come to matching the capabilities of
embryonic stem cells has become a contentious question
in the debate over whether the federal government should continue funding research
on embryonic lines.
This is
in stark contrast to much previous work, which has focused
on human
embryonic stem cells, or hESCs.
In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's first three stem - cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for human embryonic stem - cell therapies approved in 2010, according to the health ministr
In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's first three
stem -
cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed
on the heels of clinical tests for human
embryonic stem -
cell therapies approved
in 2010, according to the health ministr
in 2010, according to the health ministry.
«Australia has cutting edge capabilities
in stem cell research and is home to world - class scientists who undertake research and development
on embryonic and adult
stem cells under a clear and transparent national legislative framework,» Livesey explains.
Because burgeoning teeth depend
on information from the budding
embryonic jaw, work toward generating replacement teeth from dental
stem cells focuses
on growing them
in the desired location
in the recipient's mouth — but scientists are not yet sure the adult jaw can provide the necessary signals to shape made - to - order teeth.
Further investigation, says Resar, showed that these unusual properties arise from the ability of HMGA1 to turn
on several genes involved
in the Wnt pathway, a network of proteins necessary for
embryonic development and
stem cell activity.
ACT, which has almost gone under several times
in recent years, may now be
on the verge of conducting the nation's first trial of an
embryonic stem cell therapy, says Chief Scientific Officer Robert Lanza.
On the other hand, the problem is, you know, with
embryonic stem cells, they haven't been able to get
stem cell lines from livestock animals that can proliferate
in that way, without just sort of veering up
in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.
The final guidelines
on research with human
embryonic stem cells issued
on Monday by the National Institutes of Health set out criteria for determining which ES
cell lines can be used
in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.
Lamberth granted a preliminary injunction
on this research after hearing a petition from a group of advocates who argued that, contrary to the U.S. government's view, research
on embryonic stem cells does
in fact destroy embryos — action that is prohibited by legislation known as the «Dickey - Wicker Amendment» to the bill that funds the Department of Health and Human Services.
While conservatives
in Congress took turns echoing George W. Bush's opposition to destroying human embryos for research, Lensch's colleague Paul Lerou stepped into a small room behind a heavy black curtain to check up
on a line of nonpresidential
embryonic stem cells.
We should not only question the construct of the «ethics of curing,» as I will show, but we also need to look critically at reservations toward research
on embryonic stem cells as they are expressed
in our society.
When Kaufman, Zon and colleagues looked to see what was different about these early cancer
cells, they found that crestin and the other activated genes are the same ones turned
on during zebrafish
embryonic development — specifically,
in the
stem cells that give rise to the pigment
cells known as melanocytes, within a structure called the neural crest.
In the past few weeks, the debate about genetic research in Germany has focused on the issue of the use of embryonic stem cells for researc
In the past few weeks, the debate about genetic research
in Germany has focused on the issue of the use of embryonic stem cells for researc
in Germany has focused
on the issue of the use of
embryonic stem cells for research.
In its white paper
on stem cell research published last Thursday, the DFG's senate confirmed its position that the use of adult
stem cells has to have priority over
embryonic stem cells.
Last May
in Nature Neuroscience, his lab and a team at Columbia University reported that
embryonic stem cells could be used to shed light
on the origins of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease
in which motor neurons
in the brain die.
In June Italian scientists announced the first human
embryonic stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide
on its own, with no sperm involved.
In 2004 Blackburn and ethicist William F. May made headlines when the Bush administration ousted them from the President's Council
on Bioethics for their strong public support of human
embryonic stem cell research.
- Our results provide new insights into the mechanisms of how POLR3G gene regulates
stem cell state, which
in turn sheds light
on the complex mechanisms with which human
embryonic stem cells both self - renew and maintain the ability to differentiate.
In a statement put
on the Web this morning, NIH reported that all 64 lines «show characteristics of
stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human
embryonic stem cells.»
The National Institutes of Health (NIH) is scrambling to push out research grants for work
on human
embryonic stem cells (hESCs) and has given a cautious all - clear to
in - house
stem cell researchers after an appeals court yesterday temporarily lifted a ban
on federal funding for hESC research.
In a response to Friday's decision, NIH spokesperson John Burklow said NIH doesn't set aside fixed amounts of money for studying adult or
embryonic stem cells, but instead makes award decisions based
on scientific merit and relevance to NIH's priorities.
In the latest twist in an increasingly complex legal struggle, the Department of Justice (DOJ) has appealed a judge's refusal on Tuesday to remove the ban on funding for human embryonic stem cell (hESC) researc
In the latest twist
in an increasingly complex legal struggle, the Department of Justice (DOJ) has appealed a judge's refusal on Tuesday to remove the ban on funding for human embryonic stem cell (hESC) researc
in an increasingly complex legal struggle, the Department of Justice (DOJ) has appealed a judge's refusal
on Tuesday to remove the ban
on funding for human
embryonic stem cell (hESC) research.
As expected, the plaintiffs
in a law suit claiming that federally funded research
on human
embryonic stem cells (hESC) is illegal have appealed a ruling that dealt them a defeat earlier this summer.
Goldman's work builds
on previous studies that explored the developmental cues involved
in directing an
embryonic stem cell to become a functioning neuron.
In March, President Barack Obama lifted Bush's ban
on using federal funds for research
on human
embryonic stem cells derived after August 2001.
Democrat Hillary Clinton vows to end Bush's «assault
on science» and has been the most vocal
in her support of
embryonic stem cell research.
Scientists have suggested that such
embryonic stem cells could be used for learning about genetic diseases, testing new drugs
on cells grown
in the lab, or growing healthy
cells for therapeutic transplantation.
But
embryonic clones, the source of an endless supply of
stem cells imprinted with one's personal DNA, could alter the equation
in favor of the patient and augur a paradigm shift
in medicine
on par with the changes brought about by antibiotics and vaccines.