Sentences with phrase «on key enzymes»

Not exact matches

Though it's unclear what effect, if any, BPA may have on egg quality during IVF, «there is mounting data that a key enzyme that helps convert testosterone to estrogen may be inhibited by BPA,» said Bloom.

The Surolias went on to show that, like in bacteria, triclosan is the wrench that jams Plasmodium's fatty acid machinery; it inhibits one of the key enzymes in the biochemical conveyor belt.

That enzyme regulates the way key learning and memory - related genes turn on and off during development.

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells.

«Scientists determine structure of enzyme linked with key cell - signaling protein: Findings aid understanding of how modifications to cell - signaling protein affect its action in turning genes on and off.»

Its complex three - dimensional structure allows it to act simultaneously on two parts of a key enzyme in the tuberculosis bacillus, and in doing so, dramatically reduce the risk that the bacteria will develop multiple resistances.

Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so - called «off - target» spots on a chromosome, the development of immune cells can lead to cancer in animal models.

Yang and co-author Chunru Lin, Ph.D., an assistant professor in the same department, confirmed four sites for phosphorylation, a process that turns protein enzymes off and on, impacting key cellular functions.

The study, published in Nature Communications today, focused on protein kinases, enzymes that are key regulators of cellular processes.

The symposium will focus on the roles of the major enzymes participating in metabolism of xenobiotics including carcinogens and drugs — the membrane monooxygenase systems containing cytochromes P450 — and highlight the key advances in their mechanisms of action at the molecular level.

9/20/2007 UCSD Study Reveals the Regulatory Mechanism of Key Enzyme Protein kinase A (PKA) involved in cardiac disease and breast cancer Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalia... MoreKey Enzyme Protein kinase A (PKA) involved in cardiac disease and breast cancer Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalia... Morekey proteins in all mammalia... More...

Since invasion is dependent on extracellular matrix remodeling capabilities, this inhibitory effect strongly suggested that the two key extracellular membrane remodeling enzymes expressed by endothelial cells, namely, MMP - 2 and uPA could be other main key targets of the pharmacological action of kahweol on endothelial cells.

«Our study focused on a class of enzymes called methyltransferases, which have emerged as key regulators of HIV latency,» explained Melanie Ott, MD, PhD, a senior investigator at Gladstone and lead author of the study published in the scientific journal Cell Host & Microbe.

The Lexicon efforts are focused on gene families that are pharmaceutically important, such as transporters, G - protein coupled receptors (GPCRs), ion channels, kinases and other key enzymes, membrane proteins (e.g., receptors), and secreted proteins.

Aging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aging.

One study shows that curcumin turns on a key gene signal involved with nerve protection, which boosts antioxidant enzymes in the brain and helps to prevent neurodegeneration.

Research will be presented on the use of enzymes, botanical medicines, probiotic microflora and key strategies and protocol in the successful treatment of gastrointestinal — related chronic illness.

Lesson presentation on bacteria and different enzymes in digestion, ideal for Key Stage 3 science, dealing with how bacteria are involved in digest...