Sentences with phrase «on kidney cells»

Black people are particularly at risk, given the study's finding that suPAR activates its receptor on kidney cells that then attract the APOL1 risk proteins.

«Hydroxyethyl starch has direct harmful effects on kidney cells, lab study finds.»

Not exact matches

On an additional project with former MIT graduate student Eric Grovender, Ameer co-developed a cartridge filter that purifies blood, «based on protein and cell engineering,» for those suffering from chronic kidney failurOn an additional project with former MIT graduate student Eric Grovender, Ameer co-developed a cartridge filter that purifies blood, «based on protein and cell engineering,» for those suffering from chronic kidney failuron protein and cell engineering,» for those suffering from chronic kidney failure.

Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293 cells was dependent on added Wnt5A protein and was accomplished by the multifunctional adaptor protein β - arrestin 2 (βarr2), which was recruited to Fz4 by binding to phosphorylated Dvl2.

Both vaccines were based on live, weakened strains of polio virus grown in monkeys» kidney cells.

In kidney cancer, the over-expressed NPTX2 protein is secreted from the cell and then attaches itself to GluR4 on the kidney cancer cell membrane.

But he also has a team working on the model that occurred to him on the beach: Harvest and grow some healthy cells from a patient's damaged kidneys.

When The Cancer Genome Atlas Research Network reported its genomic profiling of clear - cell kidney tumours, about one - quarter of participants (126 patients) had been operated on at Memorial Sloan Kettering3.

They found that the mutated G1 and G2 variant did so particularly well on what's known as a receptor on the surface of kidney cells, in this case the suPAR activated receptor alphavbeta3 integrin.

«Mice engineered with rare kidney disease shed light on how cells repair broken DNA.»

The cells also wreak havoc in the kidneys, stimulating the organs to hold on to more sodium, which in turn spurs the body to retain more water.

«We are now working to create a discharge path for the kidney and combine it with our findings on glomerular cells.

Before toying with worms, the S.U.N.Y. Buffalo team tried out their technique on cultures of human embryonic kidney cells and neurons from a rat hippocampus, a part of the brain integral to memory.

Further testing of this culture method on kidney progenitor cells derived from human iPS cells resulted in four times the total amount of cells over 8 days.

To upgrade their DNA «switches,» Wong and his colleagues steered clear of transcription factors and instead switched human kidney cell genes on and off using scissorlike enzymes that selectively cut out snippets of DNA.

Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumour, the most common kidney cancer occurring in children.

In a related Comment published today in The Lancet, Jonathan Barasch, MD, PhD, professor of medicine and pathology and cell biology at CUMC, and colleagues Drs. Joseph Bonventre (Harvard Medical School, Brigham and Women's Hospital) and Richard Zager (University of Washington Medicine) explain that the blood test, which measures serum creatinine — a waste product that is removed by the kidneys and excreted in urine — only offers a snapshot of the kidney's function at a given moment, which can vary depending on individual factors such as body size and muscle mass.

An alternative possibility is that successful propagation of TMAdV may depend on infection of a specific host cell type, such as A549 lung, and not BSC - 1 or PMK kidney cells.

The scientists got another surprise when they followed up on this finding with mouse experiments that exposed specialized kidney cells called «podocytes», a key component of the blood filtering, to high levels of glucose.

To study the molecular mechanisms of kidney fibrosis, focusing on cell - matrix interactions and arachidonic acid - derived eicosanoids in kidney injury.

Increased glucose processing has long been thought to inflict damage on the mitochondria (the cell's power generators), which then produce large amounts of reactive oxygen molecules, which in turn leads to kidney disease.

$ 1.8 M Supports Cancer Drug Discovery on Commonly Mutated Gene New Brunswick Patch — April 5, 2016 Behavioral Scientist Shares Insights about FDA's Proposed Rule on Banning Tanning Bed Use among Minors News-Medical.net - March 19, 2016 Intervention Program Reduces Caregiver Distress during Hospitalization of Pediatric Stem Cell Transplant Patients News-Medical.net - March 9, 2016 Exploring Genomic Pathways in the Development of Ovarian Cancer GMNews.com - March 2, 2016 Differences in Type of Small Protein may further Elucidate Lung Cancer Risk in African Americans ScienceDaily.com - March 2, 2016 Study Looks at Post-Treatment Resources for Prostate Cancer Patients Transitioning to Survivorship News-Medical.net - February 11, 2016 Drawing the Line on Tanning Bed Use by Teens ScienceDaily.com - December 21, 2015 What Rutgers Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015 Identification of Barrier that Prevents Progression of Benign Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color of the Lung Cancer Ribbon?

Already, researchers at Vanderbilt University and the University of California, San Francisco, are collaborating on the construction of an implantable bio-artificial kidney that would contain microscopic filters and living kidney cells in a coffee - cup - size device that would work like a living dialysis machine inside the body — and provide most of the benefits of a kidney transplant.

On the other hand, there are many other tissues — notably, the kidney and articular cartilage — where p16Ink4a - expressing senescent cells appear to be a contributing factor to human and murine degenerative aging, but which were not evaluated in treated or control mice in this study, and it would be of interest to see the effects of ablation of p16Ink4a - positive senescent cells.

ARANESP ® is used to treat anemia, a deficiency in the number of red blood cells, caused by chronic kidney failure in patients both on dialysis and not on dialysis.

Viral stocks were titrated on Vero cells (African Green Monkey Kidney) supplemented with 10 % fetal bovine serum (FBS) as well as penicillin - streptomycin (1 %) and fungizone (0,05 %).

The meeting will also feature other aspects of the Human Cell Atlas initiative, including updates on progress so far towards atlases of tumour, lung, gut, kidney and immune system cells.

For more on this simple and effective approach to promote kidney regeneration, stay tuned to the Stem Cells Portal!

Petrelli A, Tresoldi E, Mfarrej BG, Paganelli A, Spotti D, Caldara R, Secchi A, Battaglia M. Generation of donor - specific T regulatory type 1 (Tr1) cells from patients on dialysis for cell therapy after kidney transplantation.

A glomerulus - on - a-chip lined by human stem cell - derived kidney cells could help model patient - specific kidney diseases and guide therapeutic discovery

«Our method not only uses soluble factors that guide kidney development in the embryo but, by growing and differentiating stem cells on extracellular matrix components that are also contained in the membrane separating the glomerular blood and urinary systems, we more closely mimic the natural environment in which podocytes are induced and mature,» said Musah.

Other scalable systems include cell lines based on the Henrietta Lacks tumor (HeLa) and baby hamster kidney (BHK - 21) cells for adenovirus serotype 5 (Ad5) and herpes simplex virus 1 (HSV - 1) production (4, 40, 41).

Primary kidney epithelial cells isolated from human proximal tubule are cultured on the upper surface of an extracellular matrix - coated, porous, polyester membrane that splits the main channel of the device into two adjacent channels, thereby creating an apical «luminal» channel and a basal «interstitial» space.

«On top of transporting nutrients to your cells and protecting your kidneys, water regulates body temperature,» Dr. Peeke explains.

But the study their claim is based on is an in vitro trial in kidney cells.

Even when overdosing for years on end, as Mr. Karason obviously did, there has still been no apparent damage to his blood cells, and no disruption whatsoever of heart, liver or kidney function.

Interestingly, the cells on the backs of our eyes, our kidney cells, and the cells of our extremities CA N'T say no.

Inhibitory non-genomic effects of progesterone on Na + absorption in epithelial cells from Xenopus kidney (A6).

The effect of diet on the gluconeogenic capacity of rat - kidney - cortex slices [5] Liver and kidney metabolism during prolonged starvation [6] Unrecognized Pandemic «Subclinical» Diabetes of the Affluent Nations: Causes, Cost and Prevention [7] Carbohydrates and Immune Function [8] Overexpression of glut1 and glut3 in stage I nonsmall cell lung carcinoma is Associated with poor survival [9] The in?uence of diet on the mucin carbohydrates in the chick intestinal tract [10] Rat intestinal mucosal responses to a microbial flora and different diets [12] Chronic Ethanol Induced Impairment of Hepatic Glycosylation Machinery in Rat Is Independent of Dietary Carbohydrate [13] Glycosylation in Cellular Mechanisms of Health and Disease [14] Metabolic Aberrations Associated with Arginine Deficiency [15] Glycerol gluconeogenesis in fasting humans

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I had a scan on kidney's 6 weeks before when first went to hospital about the stomach pain, I had white blood cells in urine.

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Like cells in our body, there are many houses on Liver Street, Kidney Road, and Pancreatic Avenue among others.

The adrenal glands, two glands that sit on top of each kidney and the Leydig cells in the testes of men and the ovaries in women produce testosterone when signaled by the brain.

Our research has shown it to be non-toxic on sensitive kidney cells, even at high usage.

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The adrenal glands are two tiny units of cells which sit on top of each kidney.

For cats whose excessive urination is caused by damage to the kidney cells, treatment will be quite varied depending on the exact cause of the damage.

Urine strip test showed no signs of any infection, but «spun» urine revealed it contained protein and white blood cells... he was put on amoxicilllian and I was advised to give him a low protein «kidney» diet and Azodyl.

Talk to your veterinarian based on the cell type, pre-surgery blood work (how is her kidney function, how is her liver function, etc?)