Sentences with phrase «on kinase enzymes»

We study the signal transduction pathways regulating cell growth and proliferation, with an emphasis on kinase enzymes.

Not exact matches

Metformin, which acts on the AMP kinase enzyme, lowers blood sugar and improves insulin sensitivity, thus altering insulin production.

Based on the current study results, the team believes a particular enzyme, «dual specificity tyrosine - regulated kinase - 1a (DYRK1A),» is the likely target of harmine.

One reason may be that DDRs are protein enzymes known as tyrosine kinases that act as on and off switches of the cell self - cleaning process known as autophagy.

When calcium floods a neuron as a memory is formed, it turns on an enzyme called CaMKII (calcium / calmodulin - dependent protein kinase).

To help on this front, in a new paper published in the journal Structure, researchers from McGill University present in atomic detail how specific bacterial enzymes, known as kinases, confer resistance to macrolide antibiotics, a widely used class of antibiotics and an alternative medication for patients with penicillin allergies.

Focusing on a particular group of enzyme - blocking compounds called protein kinase inhibitors, they identified 31 compounds that inhibit malaria growth without harming the host.

For the new study, the research team focused on activating an enzyme known as AMP - activated protein kinase, or AMPK, which — among other roles — stimulates the breakdown of glucose for energy.

The study, published in Nature Communications today, focused on protein kinases, enzymes that are key regulators of cellular processes.

9/20/2007 UCSD Study Reveals the Regulatory Mechanism of Key Enzyme Protein kinase A (PKA) involved in cardiac disease and breast cancer Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalia... More...

«It works as a huge allosteric enzyme that allows one receptor to activate 35 kinases on the other side,» he says.

The Lexicon efforts are focused on gene families that are pharmaceutically important, such as transporters, G - protein coupled receptors (GPCRs), ion channels, kinases and other key enzymes, membrane proteins (e.g., receptors), and secreted proteins.

This protein synthesis relies on all sorts of enzymes to work, from helicases that open up the DNA strand to be read, to RNA polymerases that create RNA - based on the original DNA sequence, to protein kinases.