Sentences with phrase «on laboratory mice»

However, research on laboratory mice documents changes in immune system function with pinworm infestation, so a finding of pinworms along with diarrhea, weight loss, unthriftiness or other illness merits treatment.

His research, carried out on laboratory mice, found that this short chain saturated fatty acid was successful in controlling inflammation, metabolic rate, and stress.

In testing on laboratory mouse models and human MDS / AML samples, the researchers identified a novel substrate of TRAF6 called hnRNPA1, an RNA binding protein.

Not exact matches

Influence of intermittent fasting and high - fat diet on morphological changes of the digestive system and on changes of lipid metabolism in the laboratory mouse

In 2016 an independent Italian laboratory published a large study on mice.

Testing with laboratory mice have shown negative impacts on respiratory, digestive, and reproductive systems, among others.

Laboratory tests on mice support the evidence that mixing capsaicin and cocaine makes for a very bad high.

What's more, an ointment containing the peptide effectively treated wounds infected with methicillin - resistant Staphylococcus aureus (MRSA) and the increasingly common hospital infection bacterium Acinetobacter baumannii in mice and on laboratory samples of human skin.

In laboratory tests on embryonic mice engineered to not express myomerger in skeletal muscle, the animals did not develop enough muscle fiber to live.

Experimental research on drugs, immunology, and the development of malaria is typically done on related Plasmodium species that infect rodents, including laboratory - reared mice.

He was conducting laboratory experiments aimed at finding ways to lessen the effects of cancer therapy on ovaries when he noticed that healthy female mice seemed to be losing eggs at unsustainable rates.

Researchers at the Scripps Institution of Oceanography in San Diego, California, suggest that high levels of carbon monoxide in the seals» blood has a protective effect — echoing laboratory research on rats and mice that has found the gas has anti-inflammatory properties and can lead to better outcomes after organ transplant.

Published in Neuron, scientists at Cold Spring Harbor Laboratory (CSHL) report their discovery of a neural circuit in the mouse olfactory bulb that explains how our mammalian cousins (and by extension, we) are able to adjust the gain on intense odors.

The research was done with laboratory mice that consumed different diets and then faced a variety of tests, such as water maze testing, to monitor changes in their mental and physical function, and associated impacts on various types of bacteria.

Case Western Reserve research associate Amar Desai, PhD, worked between the Markowitz and Gerson laboratories to determine the effect of SW033291 on mice that had received lethal doses of radiation and then received a partial bone marrow transplant.

Still, Zuker was adamant: Knock out either of the two subunits on the protein receptor he identified and laboratory mice lose all sense of sweet, regardless of which compounds they're given.

Chen's team focused on the dorsal root ganglion of laboratory mice, a structure near the spinal cord that is full of sensory nerve cells.

Mice born on the farm reacted less intensely to an artificial allergen than those born in the laboratory.

For comparison, bacteria grown in a laboratory on Earth in normal gravity infected another group of mice.

The findings have implications for all aspects of medical and scientific research because laboratory mice underpin studies whose results have a transformative effect on human and animal lives through vaccination and other immune - based therapies.

«What we've shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,» says Peter C. Gray, a staff scientist in Salk's Clayton Foundation Laboratories for Peptide Biology, who collaborated on the new work with Benjamin T. Spike, a senior research associate in the laboratory of Salk Professor Geoffrey M. Wahl.

The researchers had originally obtained this genetically diverse group of inbred laboratory mice to study locations on mouse genomes associated with influenza severity.

The genetic code of the mouse, published on a public Web site (www.ensembl.org), is expected to speed the work of laboratory scientists studying human diseases around the globe.

That's because most studies on single human brain cells use dead rather than living tissue, and many others rely on cells from common laboratory animals, especially mice.

In the mid-1990s, Woloschak had worked on samples from 7,000 beagles and 50,000 mice that had been irradiated in experiments at the Argonne Research Laboratory in Illinois between 1969 and 1992.

The mouse has been the mainstay of laboratory research on human illness and will most likely become a more essential player in future studies.

Carried out in cells in the laboratory, in mice and in samples from patients» tumours, the researchers showed this «safe haven» lets melanoma cells turn on a parallel set of cell signals that helps them survive.

The fundamental genetic similarity between mice and humans allows researchers to infer a human gene's function based on studies with laboratory mice.

The Jackson Laboratory celebrated the groundbreaking for its new, state - of - the - art vivarium, a 134,900 - square - foot facility to maintain research mouse models, at the institution's Ellsworth, Maine, location on August 2.

The second laboratory continues to focus attention on transplantation immunobiology in mouse models and translational studies of human immunology in transplant recipients.

In 2010, Gad2 - IRES - Cre knock - in mice on a mixed genetic background (mostly C57BL / 6; 129S4; with black coat color) were sent to The Jackson Laboratory Repository.

In 2017, a 153 SNP analysis (with markers covering all 19 chromosomes and the X chromosome) was performed on the first generation of rederived mice at The Jackson Laboratory Repository (heterozygous for the Gad2 - IRES - Cre allele).

We are currently focusing our efforts on an exceptional resource of laboratory mouse strains with proven Mendelian disorders with unknown genetic etiology, strains stewarded by the Mouse Mutant Resource at The Jackson Laboratory for overlaboratory mouse strains with proven Mendelian disorders with unknown genetic etiology, strains stewarded by the Mouse Mutant Resource at The Jackson Laboratory for over 50 ymouse strains with proven Mendelian disorders with unknown genetic etiology, strains stewarded by the Mouse Mutant Resource at The Jackson Laboratory for over 50 yMouse Mutant Resource at The Jackson Laboratory for overLaboratory for over 50 years.

«Our previous studies show the drug we are working on will reduce the symptoms of diabetes in mice by itself,» says Dr. Bruce Hammock, who runs the Hammock Laboratory of Pesticide Biotechnology at UC Davis.

U.S. Senators Susan Collins and Angus King, Congressman Bruce Poliquin, LePage administration Senior Policy Advisor John Butera and Ellsworth Mayor Robert Crosthwaite were on hand to launch the new facility, which is the first step in the Laboratory's long - range plan to gradually migrate mouse production (except for the research mice used by JAX scientists) from Bar Harbor to Ellsworth, freeing up space in Bar Harbor to expand research and education programs.

The Consiglio Nazionale delle Ricerche, European Mouse Mutant Archive (EMMA) Core Structure, Monterotondo Campus and The Jackson Laboratory offer a comprehensive workshop on cryopreservation of mouse embryos, sperm and ovaMouse Mutant Archive (EMMA) Core Structure, Monterotondo Campus and The Jackson Laboratory offer a comprehensive workshop on cryopreservation of mouse embryos, sperm and ovamouse embryos, sperm and ovaries.

In 2012 she joined the laboratory of Dr. D.L. Konotyiannis at BSRC AL.Fleming, Greece as postdoctoral scientist, where she worked on the study of the RNA Binding Protein HuR during intestinal and lung inflammation and cancer, using inducible, KO and Tg mouse models and xenografts.

In the October issue of Cell Stem Cell, Marius Wernig, MD, PhD, a NYSCF — Robertson Investigator at Stanford University, reported on the successful transformation of mature liver cells from laboratory mice into functioning neurons.

Akassoglou's laboratory uses mouse models of blood - driven neural inflammation and autoimmunity to explore further the role of fibrinogen in MS, and she is now pursuing similar lines of investigation on other neurological diseases.

CNR Monterotondo Workshop on Cryopreservation and Recovery Techniques in the Laboratory Mouse, November 07 - 10, 2016

The study focused on embryonal rhabdomyosarcoma caused by mutations in the Sonic Hedgehog signaling pathway and used a mouse model developed in Hatley's laboratory.

In laboratory experiments on mice modified to mimic the signs of MS, the team employed an Activatable Cell - Penetrating Peptide (ACPP), a special type of molecular probe that delivers fluorescent agents to a region of interest.

He is replicating the salamander studies he did at MDIBL on mice at nearby Jackson Laboratory.

Rag1 - / - mice on a C57BL / 6 background were obtained from The Jackson Laboratory (Bar Harbor, ME)[69].

We thank Xiang Gao of Nanjing University for providing EGFP - transgenic mice and members of the Ying Jin laboratory for valuable discussions and comments on the manuscripts.

She now serves as the main surgeon of the laboratory, where she continues to perform brain surgeries on mice.

Molecular basis of scouting behaviors in honey bees Zhengzheng Liang, Neuroscience Program, University of Illinois at Urbana - Champaign, USA Dissociating epigenetic mechanisms of memory in the hippocampus and perirhinal cortex of rats Krista Mitchnick, Department of Psychology, Collaborative Neuroscience Program, University of Guelph, Guelph, ON, Canada Determining the heritability of locomotor sensitization to ethanol and its relationship to ethanol's positive motivational effects in mice David Linsenbardt, Indiana Alcohol Research Center and Department of Psychology, Indiana University — Purdue University, Indianapolis, Indianapolis, Indiana, USA Rufy1 or Hnrnph1 is a likely quantitative trait gene for methamphetamine sensitivity Camron Bryant, Laboratory of Addiction Genetics, Department of Pharmacology and Experimental Therapeutics, Department of Psychiatry, Boston University School of Medicine, Massechusetts, USA

All mice were housed in our Association for Assessment and Accreditation of Laboratory Animal Care - accredited barrier facility on a 12 h light / dark cycle, and given ad libitum access to food (NIH31 Diet, Harlan no. 7917) and water.

WFSM establishes laboratory to develop transgenic and knockout mice to model human disease and shed light on function of human genes.

A series of new mouse models have recently been developed in the laboratory that will allow us to dissect how DNA damage, oxidative stress and chromatin remodeling impact on mitochondrial integrity and stem cell decline during aging.