Sentences with phrase «on laboratory models»

Research teams are also developing ways to innovate the early drug - discovery process, including pioneering methods to rapidly identify drug targets and test them on laboratory models and finding and testing new therapeutic possibilities for already FDA - approved drugs.

Not exact matches

In many dark energy models, we would expect to see significant effects on both laboratory and cosmological scales.

Testing that has been completed on components of the system, dubbed KRUSTY, has been «greatly successful — the models have predicted very well what has happened, and operations have gone smoothly,» said Dave Poston, chief reactor designer at the Los Alamos National Laboratory.

It is customary and even ethically mandatory that experimentation that carries with it a substantial degree of risk to human subjects first be tested in an animal laboratory or, at the very least, on a computer model.

The extreme cases of unambiguous wave and particle behaviour occur in mutually exclusive laboratory situations.7 As one physicist puts it, you may have to use a wave model on Mondays, Wednesdays and Fridays, and a particle model on Tuesdays, Thursdays, and Saturdays.

I have done a little work on developing model behavioral assay procedures for studying the experiences of laboratory rats.

With a laboratory machine designed as a semi-automatic model, containers can be fed into as many as 21 stations which print on four types of bottle...

Some football helmet manufacturers suggest that players who wear their helmets - especially new models - may be at lower risk of concussion than those who wear competitors» models or older helmets, basing their claims on how well the new or newer helmets absorb and lessen some of the impact forces that cause concussion in biomechanical studies performed in the controlled environment of the laboratory.

But the fact that one part of the rings didn't cool as expected allowed us to model what they might be like on the inside,» said Ryuji Morishima of NASA's Jet Propulsion Laboratory, Pasadena, California, who led the study.

We were very surprised based on the fact that previous models people used for planet formation suggested a much higher critical shock pressure,» says Richard Kraus, now a scientist at Lawrence Livermore National Laboratory and lead author on the paper published in March in Nature Geoscience.

«However, these studies were either carried out in the laboratory over short timescales or based on theoretical models.

«Astronomers observe exploding stars and astrophysicists model them on supercomputers,» said Wrede, assistant professor of physics at MSU's National Superconducting Cyclotron Laboratory.

«The problem is that most of the plant - tolerance models we currently use to predict these outcomes are based on laboratory studies or plant physiological studies, so they often don't factor in the compounding effects of simultaneous stressors like drought and pressure from natural enemies.

Modeled on such pathbreaking establishments as the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom, and Bell Labs in New Jersey, Janelia consists of small, multidisciplinary groups — approximately 45 of them when staffing reaches full strength in 2009.

«We have in the Luzon Strait an oceanic laboratory where we can test our theoretical models and simulations to see them play out on a small scale.»

The model has been validated through laboratory experiments on a human - made freak or rogue wave (the so - called «soliton splash») using test tanks.

In his groundbreaking book The Inflationary Universe, for example, Alan Guth of MIT, who codeveloped the leading model of the Big Bang, speculates provocatively about whether it would be possible to create a new universe in a basement laboratory, but he treats such a Genesis - on - demand merely as a scientific thought problem.

Today, a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Partha Mitra describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain, based on their molecular identity.

In her 4 years at Furman University in Greenville, South Carolina, Laura Glish, a 2006 graduate, worked on collaborative projects in two different laboratories and explored a variety of experimental techniques, from atomic force microscopy to synthetic chemistry and molecular modeling.

Osborne's swagger seems a bit subdued as we wind our way through the laboratories and testing pools, past scale models of tankers and oil platforms detailed down to the company logos painted on their sides (no photos allowed).

PhysiScore outperformed not only the Apgar scale but also three models that rely on invasive laboratory tests, the team reports online today in Science Translational Medicine.

Yet that's just what researchers have done, using a seemingly simple laboratory model of rifting on the seafloor.

«It's the same Olympic model going on with the laboratories,» he says.

«If human organs on chips can be shown to be robust and consistently recapitulate complex human organ physiology and disease phenotypes in unrelated laboratories around the world, as suggested by early proof - of - concept studies, then we will see them progressively replace one animal model at a time.

When projects on the scale of a nuclear power station or THORP are concerned, or the release of genetically modified organisms into the environment, to give another example, it is not possible to model them fully in the laboratory using traditional trial - and - error methodology.

Eventually, HBP wants to evolve into an international organization, Gillet says, modeled on CERN, the European Space Agency, or the European Molecular Biology Laboratory.

Such ease of use will likely encourage the use of more animal models in the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshop).

For her study on geologic storage, Lord and her colleagues analyzed and reworked the geologic storage module of Argonne National Laboratory's Hydrogen Delivery Scenario Analysis Model.

Chu also talked about modeling energy research laboratories on Bell Labs.

In order to guarantee the compatibility of these tests on a global scale, the laboratories use model species specified by international guidelines, including a species of earthworm.

«Having these personalized laboratory models, which we can make in a matter of weeks, will let us test multiple different drugs on the tumor and help us bring precision medicine to individuals with bladder cancer.»

Dan Hooper, a physicist at the Fermi National Accelerator Laboratory in Batavia, Illinois, tweeted on 26 March: «I'm a very creative dark matter model builder (if I do say so myself) and I can not come up with a viable model that can produce this signal.»

The new computational model is built on CogSketch, an artificial intelligence platform previously developed in Forbus» laboratory.

Shown are the 1988 - 2014trends in springtime ozone levels on days that were very smoggy (top panel) and of average smogginess (bottom panel), from observations (left) and from a model built by the Geophysical Fluid Dynamics Laboratory (right).

«While laboratory studies of the effect of temperature on the physiology and behavior have provided significant insights into thermal ecology of ectotherms, the time is ripe to take this knowledge outside the lab to further develop climate change models,» he said.

Greenblatt and co-author Samveg Saxena at the Lawrence Berkeley National Laboratory developed a model that is essentially a «best - case scenario,» where the cars are not just driverless but also run on electricity.

On Tuesday, Enserink followed up with a report on a study recommending that HBP «be remade into an international organization modeled on CERN or the European Molecular Biology Laboratory (EPFL) in Heidelberg.&raquOn Tuesday, Enserink followed up with a report on a study recommending that HBP «be remade into an international organization modeled on CERN or the European Molecular Biology Laboratory (EPFL) in Heidelberg.&raquon a study recommending that HBP «be remade into an international organization modeled on CERN or the European Molecular Biology Laboratory (EPFL) in Heidelberg.&raquon CERN or the European Molecular Biology Laboratory (EPFL) in Heidelberg.»

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

In testing on laboratory mouse models and human MDS / AML samples, the researchers identified a novel substrate of TRAF6 called hnRNPA1, an RNA binding protein.

Using statistical models, a team of researchers from the British Antarctic Survey and Plymouth Marine Laboratory assessed the likely impact of projected temperature increases on the Weddell Sea, Scotia Sea and Southern Drake Passage, which is known for its abundance of krill.

Researchers at MIT's Computer Science and Artificial Intelligence Laboratory have developed a new computational model of a neural circuit in the brain, which could shed light on the biological role of inhibitory neurons — neurons that keep other neurons from firing.

Through the integration of such large - scale data sets within computational models, his laboratory is unraveling condition - dependent networks of active regulation process and novel principles on the operation of metabolic networks.

Franziska Michor (Dana - Farber Cancer Institute)-- Research done at the computational biology and bioinformatics laboratory of Dr. Michor has led to the first clinical trials based on the evolutionary mathematical modeling of cancer.

This session examined the biogeochemical processes that are likely to affect the evolution of the Earth system over the coming decades, with a focus on the dynamics of marine and terrestrial ecosystems and the development of improved understanding through (a) fieldwork and laboratory experiments, (b) development of new observational datasets, both modern and palaeo, and (c) simulations using numerical models.

To save the stranded rover, NASA ran tests on a model of the rover in a simulated Martian «sandbox» at the Jet Propulsion Laboratory.

For the purposes of this Prize, research based solely on computer models will not be accepted as a substitute for ocean experiments or effective, small - scale laboratory models and experiments.

We focus on several model organisms in the laboratory but are open to additional approaches by independent - minded and motivated individuals.

The following profile of REGEN2017 student Susannah Kassmer, Ph.D., appears in the fall edition of the MDI Biological Laboratory's «Breaking Through» magazine, which focuses on how the study of highly regenerative animal models can help science understand the potential for regeneration in humans.

Recent in - situ measurements at the Martian surface by the RAD instrument (Hassler et al. 2012) on board the Mars Science Laboratory rover agree relatively well with the quiet - time GCR predictions made by these computational modelling efforts (Hassler et al. 2014; Kim et al. 2014; Gronoff et al. 2015).

The Jackson Laboratory celebrated the groundbreaking for its new, state - of - the - art vivarium, a 134,900 - square - foot facility to maintain research mouse models, at the institution's Ellsworth, Maine, location on August 2.