The included birth defects were based primarily on case reports of outcomes occurring in association with Zika virus infection during pregnancy; there is more evidence for some of these birth defects than for others, and a causal link has not been established for all.5,10,12,21 - 27 Because much of the focus to date has been
on microcephaly and brain abnormalities, data were summarized in 2 mutually exclusive categories: (1) brain abnormalities with or without microcephaly regardless of the presence of additional birth defects and (2) neural tube defects and other early brain malformations, eye abnormalities, and other consequences of central nervous system dysfunction among those without evident brain abnormalities or microcephaly.
Not exact matches
Earlier
on Friday, U.S. health officials published a study estimating that as many as 270 babies in Puerto Rico may be born with the severe birth defect known as
microcephaly caused by Zika infections in their mothers during pregnancy.
Health officials
on Friday reported the first baby born in New York City with the Zika - related birth defect known as
microcephaly, a condition marked by an abnormally small head and impaired brain development.
The Society for Maternal - Fetal Medicine released a statement
on the use of ultrasound screening for fetal
microcephaly following Zika virus exposure.
«Using ultrasound screening for fetal
microcephaly: Statement
on ultrasound screening for fetal
microcephaly following Zika virus exposure.»
«We've been seeing growing evidence of the association between Zika and congenital central nervous system malformations, not just
microcephaly, since the first cases were picked up,» says Wim Van Bortel, senior expert
on vector - borne diseases at the European Centre for Disease Prevention and Control in Solna, Sweden.
Brazil said
on Friday the number of confirmed and suspected cases of
microcephaly in Brazil associated with the Zika virus has risen to 5,131 from 4,976 a week earlier.
Stella Guerra performs physical therapy
on an infant born with
microcephaly in Recife, Brazil.
«Thus, it is tempting to speculate that the alterations induced by Zika virus
on the host cytoskeleton might be connected to the underlying physio - pathological mechanisms that link congenital Zika virus infections to
microcephaly and neurodegenerative disorders.»
Wong: I can't put percentages
on that yet, but I would say that although there are still plenty of people who believe that the original interpretation is correct, there are an increasing number of people who at least think that the hypothesis of pathology, like this
microcephaly, has not yet been sufficiently ruled out.
Two rare conditions — a birth defect (
microcephaly) and Guillain - Barré syndrome — are undeniably
on the rise.
To build their tool, Alison Galvani, from Yale University in New Haven, USA, and colleagues focused
on the two known serious consequences of Zika infection:
microcephaly, a condition in which children are born with a small brain causing mental impairment, and Guillain - Barré syndrome or GBS, a potentially fatal disease that can cause neural damage and paralysis.
He says more work
on human cells and in nonhuman primates is needed to confirm whether this mutation is really the culprit in
microcephaly.
By February 2016, the World Health Organization had declared the epidemic a global public health emergency, based largely
on the virus» newly - established link to
microcephaly and other major birth defects in babies born to infected mothers.
Although Zika causes no harm in most people it infects, its possible role in clusters of
microcephaly in babies and Guillain - Barré syndrome in adults led the World Health Organization
on 1 February to declare that it is a «public health emergency of international concern.»
«Zika virus may cause
microcephaly by hijacking human immune molecule: Fetal brain model provides first clues
on how Zika virus blunts brain development; blocking mechanism reduces cell damage.»
Though much of the concern in the media regarding the toxic effects of Zika virus has focused
on brain findings of
microcephaly, the researchers noted that there are a variety of brain abnormalities that can be found in fetuses exposed to the virus, including gray and white matter volume loss, brainstem abnormalities, calcifications, and a condition called ventriculomegaly, where the ventricles, or fluid filled spaces in the brain, are enlarged.
Future studies of these cells are expected to shed light
on developmental diseases such as autism and schizophrenia and malformations of brain development, including
microcephaly, lissencephaly and neuronal migration disorders, they say, as well as age - related illnesses, such as Alzheimer's disease.
Based
on that, we recommend using the term congenital Zika syndrome instead of
microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.
However, working
on the assumption that Zika is the cause of
microcephaly, one obvious next question would be: has some recent genetic change in the virus generated this new symptom?
If
microcephaly was being driven by some particularly nasty mutation, the cases would be more clustered together (
on the tree, if not necessarily in space and time).
«We are also launching further studies to determine whether children who have
microcephaly born to mothers infected by the Zika virus is the tip of the iceberg of what we could see in damaging effects
on the brain and other developmental problems.»
Working in laboratory mice, they injected the most abundant of these small RNAs into the mouse brain to assess the impact of each
on brain development, including whether they caused
microcephaly.
Based
on data from population - based birth defects surveillance programs for 2009 - 2013, the median prevalence of
microcephaly in the United States was approximately 7 per 10000 live births.29 There are no published estimates of the prevalence of the birth defects potentially related to Zika virus infection during pregnancy combined.
On Wednesday, U.S. health officials reported that traces of the Zika virus had been identified in the tissue of two babies who died in Brazil from
microcephaly.
All
on my facebook page angela coral eisenhauer So thanks Kelly Brogan, if you want to write an article
on Why the rise of 500 % in
microcephaly in the USA, since 2010.
To see the alternative story about Zika infections, Mike Adams, the Health Ranger, did some studies
on Brazilian populations with a high incidence of
microcephaly and did find that the incidences of
microcephaly corresponded more with environmental toxins.
Based
on a newly published systematic review of current research, WHO has reaffirmed its position that Zika virus infection during pregnancy is a cause of congenital brain abnormalities, including
microcephaly, and refined its position
on the relationship between Zika virus infection and Guillain - Barré syndrome, stating that Zika virus infection is a trigger of Guillain - Barré syndrome.
But in and around the tropics, public health officials and communities are already fixated
on the rapid spread of the virus, particularly given signs (but not yet direct evidence) that Zika is causing the devastating brain malformation
microcephaly in babies born to some infected women in affected zones in Brazil and elsewhere.
A Brazilian researcher's work
on autism has revealed possible explanaitions linking Zika virus with
microcephaly.
«There was one special needs boy with
microcephaly in my classroom who hadn't spoken in 10 years and when I pushed him
on the swing in the playground he counted to 10 for me and brought me and the teacher to tears.»