Sentences with phrase «on microglial cells»
LDN is an anti-inflammatory agent in the central nervous system, via action on microglial cells.
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Building on the evidence that microglia were in play during injury, the researchers conducted tests in zebrafish with the specialized enzyme incorporated into both rod cells and microglial cells, removing both cell types to ask what role microglia play during regeneration.
In both groups of mice, the expected deleterious effects on memory and learning didn't arise if EP2 within microglial cells was absent, as a result of a genetic manipulation.
But on the other, microglial inflammatory mediators modulate immune cells, act on neurons, and have been shown to contribute to neurodegenerative effects.
«Activation of microglial cells is, on one hand, beneficial for neuronal tissue, as it stimulates clearance of cell debris and prompts secretion of several neurotrophic factors.