Sentences with phrase «on model organisms»

Many of the annotations below, are modified or copied from the Wikipedia article on Model Organisms: Model organism.

Geneticists across the model organism and human genetics communities recognize Hieter for his dedication to uniting human biologists with those who work on model organisms such as mice, fruit flies, worms, and yeast.

He has also founded and co-led several multidisciplinary meetings that bridged the gap between biologists working on humans and those working on model organisms.

«By means of basic research on model organisms, we are trying to understand human genome instability to identify elements, which, in the future, might be able to be explored as targets of new anti-tumour medicines,» explains the researcher responsible for the project and director of Cabimer, Andrés Aguilera.

Not exact matches

What Whitehead denotes as the «social order» of the higher living beings can no longer be understood on the model of a society with its emphasis on multiplicity, but only on that of an organism focusing on unity.

The main influence (e.g., on my notion of morphogenetic fields) was the idea that nature should be founded on the model of the organism and not on the model of the machine.

People who make cybernetic models of unicellular organisms now consider the unicellular organism as being imprinted and re-imprinted on by external changing stimuli.

Currently, I work on three directions: (1) cell motility and the cytoskeleton, (2) modeling of physiology and diseases (such as autoimmune diabetes), and (3) swarming and aggregation behaviour in social organisms.

Geneticists and information scientists have built and are building models for the transition of organic molecules to self - replicating living organisms, based on theories of Earth's early development provided by astronomers, geologists, and oceanographers and on the evidence of fossilized microorganisms discovered by paleontologists.

Abrams works on jellyfish, and he suggested that one of these creatures would be a suitable model organism, because jellies have neurons but no central nervous system.

She did her master's degree research project at the Institute of Biochemistry and Biophysics (IBB), also in Warsaw, looking at the effect of genetic mutations on the function of an enzyme involved in the biosynthesis of heme, using Saccharomyces cerevisiae as a model organism.

The report, which drew heavily on two Environmental Protection Agency (EPA) workshops held in 1995, also recommends more research on such topics as DNA biomarkers that can gauge an organism's exposure to endocrine disruptors; models for predicting how endocrine disruptors are metabolized; mechanisms of how endocrine disruptors act at a cellular level; and the effects of mixtures.

In this open challenge to the status quo, he promotes an alternative strategy he calls «natural security»: the idea that we can model our own strategies on the survival techniques of highly successful organisms.

«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»

Replacement alternative methods include the use of data concerning the physicochemical properties of chemicals; predictions based on structure - activity relationships, including the use of qualitative and quantitative mathematical models; the biokinetic modelling of physiological, pharmacological, and toxicological processes; experiments on lower organisms not classed as?

Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology.

But geneticists chose Arabidopsis as their model organism based on its relative genetic simplicity, as well as its short generation time.

When projects on the scale of a nuclear power station or THORP are concerned, or the release of genetically modified organisms into the environment, to give another example, it is not possible to model them fully in the laboratory using traditional trial - and - error methodology.

The research team conducted experiments on the roots of Arabidopsis, a plant often used as a «model organism» in plant biology and had its genome fully sequenced in 2000.

In experiments on the fruit fly model organism Drosophila melanogaster, Heidelberg University biologists gained new insight into how feeding behaviour is encoded and controlled.

In a 2012 paper in Neuron, based on meetings organized by the Oxnard, California - based Kavli Foundation, Yuste and colleagues laid out a plan to progress gradually from mapping the brain activity of simple model organisms such as the fruit fly to charting the brains of creatures that contain roughly 1 million neurons, such as the Etruscan shrew.

Follows says that, with more data on these opportunistic organisms, he hopes to improve the model to accurately reflect mixotrophic populations and their effect on the planet's carbon cycle.

Most labs focus on just one model organism, he says, but he believes that keeping both in play was an important factor in his success.

Niyogi worked on identifying tryptophan biosynthesis pathways in Arabidopsis, which at the time was a relatively new model organism.

«One of the things that appealed to me [about Fink's lab] was working on more than one model organism, applying insights from yeast genetics to Arabidopsis,» Niyogi recalls.

The project was based on gene expression data from the modENCODE project, which aims to provide the scientific community with a comprehensive encyclopedia of functional elements of the genome of model organisms.

But while most research on impending environmental disaster relied on computer models, Biosphere 2 represented a fascinating alternative mode in which large - scale analog experiments employed real organisms, soil, seawater, and air.

«Our results are based on the expression of genes in two model organisms.

Given his training in developmental biology, Raman focused the team to seek a novel drug target on genes important to the development of model organisms — fruit flies (Drosophila) and yeast (Saccharomyces cerevisiae)-- rather than on oncogenes that transform a normal cell into a cancer cell.

This program, McKnight Technological Innovations in Neuroscience Awards, focuses on «how technology may be used or adapted to monitor, manipulate, analyze, or model brain function at any level, from the molecular to the entire organism.»

The experiments in Bayreuth, which also included several doctoral researchers — concentrated on the thale cress (Arabidopsis thaliana), a common plant in the fields of Europe and Asia that has proven to be a useful model organism in biological research.

For Millikan, «stored solar energy» must have meant fossil fuel, a tank of which today could be exchanged for enough cash for what was then a down payment on a 1931 Ford Model A. Fossil fuels, of course, are just aged and tenderized organisms that long ago converted sunlight into energy or fed on organisms capable of converting sunlight into energy.

We conducted surface colonization experiments using V. cholerae, a model organism for biofilm formation on a broad range of surfaces.

Scientists rely heavily on such model organisms to identify common genes, proteins and processes that underlie human medical conditions.

As our role in the HapMap concluded, we took on a new grant: constructing the genetic map of C. briggsae, a small roundworm similar to the well - known model organism, C. elegans.

We focus on several model organisms in the laboratory but are open to additional approaches by independent - minded and motivated individuals.

A group of TAGC attendees concerned about the future of model organism databases took the opportunity to start #saveMODfunding on Twitter.

A full realisation of the medical potential of stem cells for human health will likely depend on a reinforcement of, and development of a whole continuum of studies ranging from those in vivo using model organisms, to cell - based therapies in the clinic.

At the end of his talk, Collins urged researchers to continue to ask congress to fund more for fundamental research, arguing that increased, sustainable funding will help maintain support for model organisms, and the biomedical advances that depend on them

«Amy's video is both beautiful to watch on an aesthetic level and beautiful to watch as an illustration of how simple model organisms like Ashbya can give us insights into human diseases like Alzheimer's,» Atkinson continues.

Toxicology and compound testing The zebrafish model system is ideal for testing biological effects on tissue homeostasis and organism development of substances and pollutants.

Our strategy is based on the combination of genetics, imaging, electrophysiology and biochemistry in the nematode Caenorhabditis elegans (for more information on C. elegans see «an overview of the model organism C. elegans»).

However, since optogenetics is reliant on genetic modification, its use is primarily limited to relatively few model organisms.

Dr. Hansen's group focused on investigating the molecular mechanisms by which the nutrient sensor TOR modulates aging, using the nematode C. elegans as her primary model organism.

This year the organizers overtly recognized the history of our biomedical research niche in which C. elegans nematodes are used as a model organism (see our SAGE blog on how C. elegans models are used to study aging).

Prioritizing Studies on Regeneration in Nontraditional Model Organisms Regenerative Medicine / Future Science Group · December 8, 2016

We will mine and exploit information from studies and screens in model organisms, but our primary focus is on the paradigmatic mammalian stem cell systems - haematopoiesis and epithelia in vivo, and embryonic and neural stem cells in vitro.

Now we are embarked on experiments that will show improvements in both healthspan and lifespan in model organisms from mice to primates.

Physiological based pharmacokinetic models (PBPK) have been incorporated into food web models to better predict tissue levels and effects on the individual organism.

As bioinformatics approaches can only provide partial solutions, a functional analysis pipeline, based on primary (fibroblast) cell cultures, induced Pluripotent Stem cells (iPS) or simple model organisms, is truly essential.