Sentences with phrase «on mouse studies»

Based on mouse studies conducted both at UW and elsewhere, they anticipate the drug «could increase healthy lifespan of middle - aged dogs by 2 - 5 years or more.»

Now, this was originally all based on mouse studies, so we really didn't know what to think.

In a report on the mouse studies, published online Sept. 11 in PNAS (Proceedings of the National Academy of Sciences of the United States of America), the investigators say the genetic alteration appears to release the biochemical «brakes» on brain cells involved in body movement, reasoning and perception of the world, triggering over-excited activity and reactions.

As a basis for their experiments, the researchers drew on mouse studies that have identified key regulatory mechanisms acting within and between different cell types to coordinate developmental programs.

While the gene encoding the Y6 receptor is altered in man, Professor Herzog believes it would be unwise to ignore it because the development of anti-obesity drugs relies heavily on mouse studies.

Based on mouse studies, the researchers suspect that the cone cells of people with achromatopsia are not permanently damaged and could be revived by enhancing the pathway that regulates the unfolded protein response.

What seems to be happening, based on mouse studies, is that when you breathe dirty air, your brain inflames in reaction.

Not exact matches

In a new study based on mice, scientists at Lancaster University found that a drug that goes after three diabetes - related targets «significantly reversed the memory deficit» in mice who got the drug, as measured by their performance in a maze test when compared to mice who didn't get the drug.

Studies have found that the additive increases risk of certain types of cancer in mice and the International Agency for Research on Cancer classifies byproduct 4 - Mel as «possibly carcinogenic to humans.»

Some handy tools include ClickTale, which offers both mouse - move and click heat maps and starts with a freemium plan where you can study up to 400 page views a month, and CrazyEgg, which focuses mainly on heat mapping and starts at $ 99 a month.

Yet he believes the experiment he was working on is so vital, studying the impact of a toxic enzyme on mouse livers, that he begs to return on his severance to complete it.

There are some very interesting studies on this subject especially when you get into the heads of dolphins, ducks and mice.

In 2016 an independent Italian laboratory published a large study on mice.

While curcumin has been shown to prevent depression, reverse liver damage, and prevent and treat Alzheimer's, my mom can go ahead and unarch that eyebrow — the majority of the studies showing the dramatic results have only been done on mice and rats.

Studies on mice and in fertility clinics both concluded that a man's fertility drops 50 % between 40 and 45 and drops 10 % each year after.

The study on mice showed that omega - 3 fatty acids (OFAs), found in flax, hemp and fishoil «can effectively suppress fine particle - induced chronic inflammation, whether as an interventional or preventative measure.»

For example, Dr. Hugh S. Taylor, professor and chief of the Division of Reproductive Endocrinology and Infertility in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale University, studied the effects of non-ionizing radiation on the fetuses of pregnant mice.

CONCLUSIONS: Our study suggests that high folate intake may have adverse effects on fetal mouse development and that maternal MTHFR deficiency may improve or rescue some of the adverse outcomes.

One study found brain hemorrhages in mouse fetuses exposed to pulsed ultrasound at doses similar to those used on human babies.

More work has to be done on humans as many of the results showed up in mice samples, however in studying the human brains of women who had AD scientists found significantly less male fetal tissue in their brains as in the same of women who did not have AD.

And recently, a study on mice found that dioxins, present in all of us thanks to bioaccumulation, may also play a part in poor breastmilk production.

Depending on results from further behavioural studies in mice and humans, the abnormalities could then be treated in parallel with seizures.

Because companies have resources — reagents, proprietary mouse models, the ability to conduct toxicology studies, and so on — that even major research universities may lack, Giger says.

In addition to shedding light on how abnormal glia can cause schizophrenia, the study underlined how readily mouse brains accept human cells.

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

The researchers used two genetic lines of mice in the study to focus on AHR.

«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older mice, while corroborating the opposite effect among young mice,» wrote Susan Weiss, director of the Division of Extramural Research at the National Institute on Drug Abuse, who was not involved in the study, in an e-mail.

A study in mice published on June 16, 2016 in PLOS Pathogens suggests a critical role of mosquito saliva in the outcome of dengue virus infection.

Studies with mice show that specific nerve cells get turned on when they get in their nests — or anything resembling a conventional nest.

On reanalysing data from the group's past studies, such as on pain sensitivity to hot water, the researchers found that mice tested by men showed lower baseline pain sensitivity than mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being at Stanford University in CaliforniOn reanalysing data from the group's past studies, such as on pain sensitivity to hot water, the researchers found that mice tested by men showed lower baseline pain sensitivity than mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being at Stanford University in Californion pain sensitivity to hot water, the researchers found that mice tested by men showed lower baseline pain sensitivity than mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being at Stanford University in Californion nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being at Stanford University in California.

In a study published in the current issue of Neuron, researchers showed mice lacking ErbB4 activity in specific brain regions performed poorly on timed attention tasks.

The duo admits they have little evidence to back up their proposal, but they point to studies in their lab on mice, which were altered to be susceptible to both BSE and scrapie prion infection.

Studies involving mice also helped to answer a key question: What turns on the activity of the per and tim genes in the first place?

The clinical trial in humans was based on positive results of a study in mice published in Nature Communications in Sept. 2015.

In a study, when mice ate broccoli with their regular diet, they were better able to tolerate digestive issues similar to symptoms of leaky gut and colitis than mice that were not placed on a broccoli - supplemented diet, according to Gary Perdew, the John T. and Paige S. Smith Professor in Agricultural Sciences, Penn State.

Interestingly, previous studies on mice have shown that transglutaminase 4 plays an important part in male fertility.»

The study, sponsored by the Office of Naval Research (ONR) Global, involved the use of Transcranial Direct Current Stimulation, or tDCS, on the mice.

To study this question, the researchers focused on the grey mouse lemur, a small primate whose lifespan (around twelves years) makes it a very good model for the study of aging.

The study found that a mother mouse can pass along to her offspring a susceptibility to intestinal disorders, such as inflammatory bowel disease, by way of a gut - residing bacterium called Sutterella, the researchers reported in the journal Nature on Feb. 16.

Researchers Bence György and Cyrille Sage, first authors on the study, injected exo - AAV preloaded with the missing gene into the inner ears of mouse pups, shortly after birth.

In the study, researchers worked with a mouse model that has a debilitating mutation on one of the exons of the dystrophin gene.

The results of his study done on cells and mice were published this month in the journal Diabetes.

Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut microbiota in humans, and humans could be a good model to study the nutrition of dogs.

The implications of Wilson's paper and his own studies on mice were «anything but subtle,» he says.

Previous studies on mice showed that Nanotax had a ten-fold higher maximum tolerated dose compared to paclitaxel.

The authors went on to study young mice with white - matter nerve damage similar to that seen in premature babies.

Those mice actually die from Zika infection, making it difficult to study the natural transmission of the virus from father and mother to fetus and to assess the effect of this transmission on the newborns.»

Most studies of mouse social hierarchy have focused on more aggressive behaviors such as how male mice might pick on new cage members, says Helmut Kessels, a neurologist at the Netherlands Institute for Neuroscience who was not involved with the research.

A new study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia - like behavior.

From this, Rader and colleagues had a hunch, based on their knowledge of SCARB1 function and previous studies in mice, that having the SCARB1 P376L mutation, despite raising HDL, might paradoxically increase the risk of heart disease.