Sentences with phrase «on multiple cycles»

The Sun's total energy output varies on multiple cycles and is related to the number of sunspots, with slightly higher temperatures when there are more sunspots, and vice versa.

Not exact matches

Thirty - eight months — and multiple operations and physical - therapy sessions later — Phinney is now riding his first Tour de France, on pro cycling's biggest stage, where he has found immediate success.

Similarly, looking at it from an enterprise value basis, assuming a free cash flow margin of 25 % for FY18 (consensus estimates are at 24 %) on sales growth of 12 % (in - line with consensus) along with a EV / FCF multiple of 11x (in - line with the peak multiple leading up to the iPhone 6 cycle), we come up with a stock value in the mid $ 160s as well.

Our Investment Strategy Report published on March 19 compared equity and bond yields over multiple business cycles and found that the 10 - year Treasury yield might have to sustain levels exceeding 3.5 % (far above what we believe is likely this year) before compelling a year - end 2018 S&P 500 Index target range below our current year - end target of 2800 - 2900.2

«We're entering year nine of the longest uninterrupted auto credit cycle on record, and auto makers and suppliers will find it hard to push earnings much higher, which will drive them to get creative on expanding the multiple.

By having multiple products that flourish in different economic cycles, brokers can have other profit avenues to concentrate on or substitute in times when commercial mortgages are going through a slow period.

The S&P 500 registered a record high after an advancing half - cycle since 2009 that is historically long - in - the - tooth and already exceeds the valuation peaks set at every cyclical extreme in history but 2000 on the S&P 500 (across all stocks, current median price / earnings, price / revenue and enterprise value / EBITDA multiples already exceed the 2000 extreme).

The sales cycle on these business leads are typically long and require multiple sales calls over several weeks and months.

New decision - making and buying cycle processes are now being based to a high degree on social interactions between multiple parties.

The chart below is over 120 years of S&P P / E multiple history using Robert Shiller's CAPE (cyclically - adjusted P / E ratio — adjusted for total business cycles as opposed to conventional P / E's focusing on one year's data).

He recognized early on that applying leverage to safe, cheap, high - quality stocks would magnify returns without the risk of fire - sale, allowing him to stick to the principles outlined above over the course of multiple economic and market cycles.

That would be a red flag to anyone with a sense of sanity) 5) Being a convicted con — it makes sane sense that this convicted con - artist also had a thing for young girls and multiple wives (how convienient if one is in a monthly cycle, chances are he could get the boo - ty from another — and keeping them below legal age is an added treat for a pedophile - oriented putz) 6) I'm still stuck on the multiple boo - ty thing... was a great thing in my younger days but I grew into self - reponsibility to my mate and offspring 7) I'm still stuck on the Black thing in Mormonisim — banned until recent time.

I've presoaked in SHOUT overnight, I've run hot cycles with just vinegar, multiple rinses and soaks...... I'm going to try Dawn dish soap to soak them in next and maybe some essential oils that are suppose to help cut the «grease» maybe if it's oily protein stuff hanging on to the fabric ~ I also read that it could be fungus forming and eating at the oily fats??? I really hope that's not the case ~ I kept thinking I can NOT be the only one with this problem ~ I just wish I knew how to resolve it!!!!

Unlike in 2008, when those events were largely viewed only on televisions, voters this cycle were increasingly likely to watch on multiple screens.

«In 2014 Hanna won the Independence Party's nomination (New York allows candidates to accept multiple parties» nominations) and if he does the same thing this cycle, he'll have a spot on the general election ballot.

Multiple Effects Of Chinese Herbal Medicine SBEL1 On Hepatitis C Virus Life Cycle.

«These data show that if there is a national policy to transfer only one embryo per cycle during assisted reproduction, this not only lowers the rates of multiple pregnancies, but also has an important effect on the health of the single baby,» she said.

This study, which will be published Oct. 24 in eLife, and two other new Northwestern studies in Oncotarget and Cell Cycle by the Peter group, describe the discovery of the assassin molecules present in multiple human genes and their powerful effect on cancer in mice.

The results also support the theory that multiple pregnancies induce metabolic stresses on females that have heritable consequences and may be part of an obesity cycle between mothers and offspring.

Through combining results across multiple disciplines, we will learn new information about our planet's past and gain knowledge on subglacial processes such as carbon cycling and water - ice dynamics.

It supports researchers at national laboratories, universities and research institutes focused on developing and testing the next generation of adsorbents that will exhibit higher adsorbent capacity, faster binding and lower degradation over multiple use cycles in seawater.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

Starting in 2008, EnerVault began fixating on the iron - chromium «redox flow» model, improving its ability to retain its capacity over multiple cycles and making other improvements.

She's also the author of multiple books on cycling and nutrition, and writes for fitness and fashion magazines and sites.

IVF can be scary and overwhelming, but during my multiple IVF cycles, I learned that a little bit of advance preparation and organization can help you feel more... [Read more...] about My new Kindle book, Preparing for IVF, is FREE on Amazon

He'll talk to himself * as * each past role, carrying on conversations while cycling through multiple voices at a time.

In the last few years I have come to realise the merit of asking students for feedback on my practise, but I determined that it should be increased in frequency, across multiple subjects or curriculum areas, and at various points of the teaching and learning cycle if I was to be the best teacher I could be.

In Williams v. California, for example, teachers, parents, and students from low - income communities described overcrowded schools that had to run multiple shifts each day and multiple shifts during the school year, alternating on - months and off - months for different cohorts of students cycling in and out of the building; classrooms with more than 40 students without enough desks, chairs, and textbooks for each student to have one; lack of curriculum materials, science equipment, computers, and libraries; and crumbling facilities featuring leaky ceilings and falling ceiling tiles, sometimes overrun with rodents, and lacking heat and air conditioning.

Unless any new assessment system is accompanied by systems of multiple indicators to mute the distortions implied by Campbell's law, teacher capacity building to support better classroom practices, and greater emphasis on short - cycle formative classroom assessment to guide instruction, we may be doomed to repeat, in Groundhog Day — fashion, the frustrations of the past.

Students cycle through different intensives three times a year, giving teachers multiple opportunities to adjust placements based on individual needs.

These allow up to five separate fuel pulses per cycle — usually in rapid succession during the compression stroke — with multiple spark events to optimize horsepower or efficiency, depending on engine load and rpm.

Controls positioned on the left side of the steering wheel allow the driver to cycle the DII display through multiple screens of information.

Controls positioned on the right side of the steering wheel allow the driver to cycle the DII display through multiple screens of information from sources including LKAS, ACC and more, when equipped.

Controls positioned on the right side of the steering wheel allow the driver to cycle the MID display through multiple screens of information from sources including Lane Keeping Assist System (LKAS), Adaptive Cruise Control (ACC) and more.

Six fictional characters tell their tales on this historic day in cycles of linked poems alongside the perspectives of historic figures and other march participants for a rich tapestry of multiple points of view.

Jeff Jaffe, CEO of the W3C, spoke on «frictionless publishing» — the idea that the web standards (HTML or XML) that we use to build ebooks could be used throughout the whole publishing life cycle, thus avoiding the multiple transformations of most publishing processes (e.g., Word > InDesign > EPUB).

Small debit card transactions conducted on the same day at a single merchant and / or multiple transactions made during a condensed time period particularly near the end of a Monthly Qualification Cycle are not considered normal day - to - day spending behavior.

During 2004 a leading quantitative analyst predicted the the market multiple on the S&P 500 stocks would decline as interest rates increased, reflecting the Fed's tightening cycle.

If you're in multiple CRE sectors in a lot of markets hopefully you have someone on your team or can hire a consultant (like Ashworth) to chart those cycles.

If you look at periods where the price / peak earnings multiple was 16 or higher on the S&P 500, the final rate hike of a tightening cycle was actually associated with losses on an annualized total return basis, averaging -7.18 % over the following 6 months, -9.94 % over the following 12 months, and -5.87 % over the following 18 months.

A frequent speaker at precious metals conferences and in the financial media, he is one of the handful of experts who have succeeded through multiple bull and bear cycles on the strength and skills honed during the dramatic fluctuations of the 1980s.

This 4 step cycle sometimes needs to be executed multiple times until the questionable items have been removed and as each new cycle begins, hopefully there will be less questionable items on your credit reports.

AMG Yacktman Fund's 25 year track record of investing through multiple market cycles demonstrates how an investment approach focused on risk adjusted returns may help clients outperform over the long term.

The construction business likely has more than a few years left in its cycle, and as mining bottoms out the multiple should expand on the stock as it trades more in line with earlier cycle levels.

The other option is to setup the unit on automatic mode for multiple cats where a cleaning cycle starts 30 minutes after a cat uses the unit.

Catego not only kills adult fleas on contact, it breaks the life cycle, which protects against multiple stages of the flea cycle and flea re-infestation.

If a breeder has multiple litters annually, advertises puppies for sale constantly and / or breeds females repeatedly on consecutive heat cycles, potential puppy buyers should walk away, and walk away fast.

Located on Railway Terrace and connecting with Park Road café precinct, The Milton is among the finest hotels near Suncorp Stadium, seamlessly connecting residents and guests with the city and beyond, presenting the option to walk, cycle or ride, or take advantage of multiple public transport choices.

I am about to reach my first billing cycle and have multiple United flights credited on the card but haven't seen the credit posted.

Of course Call of Duty is actually on a two - year developement cycle as well, but that's thanks to having multiple teams working on the title, but that also means they release a new title every year.