Sentences with phrase «on new clinical studies»

«It also brings in the question of diet,» says Wargo, who is now working on new clinical studies on the microbiome with the Parker Institute for Cancer Immunotherapy.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

A clinical study was conducted in1999 - 2000 at Waikato Hospital in Hamilton, New Zealand using UMF ® Manuka Honey on unresponsive skin ulcers and chronic infected wounds.

Dr. Furr then completed her clinical psychology internship at the NYU Child Study Center - Bellevue Hospital Center in New York City, where she stayed on for her Postdoctoral Fellowship in the Institute for ADHD and Disruptive Disorders, and specialized in treating young children with selective mutism and oppositional problems and providing organizational skills training for children with ADHD.

The findings can prompt development of innovative therapies and new clinical studies that capitalize on the mechanisms of MAPK inhibitor addiction.

By taking a high - cost drug with a low - fat meal — instead of on an empty stomach, as prescribed — prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).

The IU team is now planning studies in animals and, ultimately, will look to others to partner on clinical trials that implement the new treatment in humans.

A new study suggests that non-violent video games that capitalize on such storytelling have prosocial benefits that could ultimately be helpful to clinical disorders such as autism.

«We are pleased to have demonstrated such a potent and durable immune response to the vaccine,» said the study's lead author, Sita Awasthi, PhD, a research associate professor of Infectious Diseases at Penn. «If found effective in clinical trials, the vaccine will have a huge impact on reducing the overall prevalence of genital herpes infections and could reduce new HIV infections as well, especially in high - burden regions of sub-Saharan Africa.»

In addition to its clinical value, the new study also sheds some light on the nature of consciousness.

The optical prosthetics, tiny enough to be balanced on a fingertip, dramatically improved the vision of about two thirds of the 206 patients studied in a 24 - month clinical trial, according to a new study published in Archives of Ophthalmology.

Women who have high levels of both testosterone and estrogen in midlife may face a greater risk of developing benign tumors on the uterus called uterine fibroids than women with low levels of the hormones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

The first - of - its - kind study found the dual treatments to be safe and elicit a clinical response in patients, according to new results from a phase I trial to be presented at the AACR Annual Meeting 2015 on April 19.

In three new studies in the current issue of the International Journal of Infectious Disease, researchers reported on clinical outcomes in the Kingdom of Saudi Arabia (KSA), how long patients will shed virus during their infections, and how the Sultanate of Oman is dealing with cases that have appeared there.

Clinical judgement, combined with an electrocardiogram (ECG) and blood test on arrival, is effective in reducing unnecessary hospital admissions for chest pain, a new study shows.

The study can be seen in Cell Reports and provides an explanation for why the clinical trials for Alzheimer's disease drugs have failed and gives new light on the discord between preclinical and clinical findings.

In a new study, a hospital surveillance program focusing on reducing the risks of sepsis, known as the two - stage Clinical Decision Support (CDS) system, was found to reduce the risk of adverse outcomes, such as death and hospice discharge for sepsis patients, by 30 % over the course of one year.

The Institute for Clinical and Econonic Review (ICER), an influential non-profit that studies the cost effectiveness of new drugs, is holding a meeting to review Luxturna on Jan. 25.

A new study by researchers from the University of Chicago Medicine, based on a 6 - month clinical trial, finds that use of a CGM is cost - effective for adult patients with type 1 diabetes when compared to daily use of test strips.

Dr Siddharth Banka, Clinical Senior Lecturer at the Manchester Centre for Genomic Medicine, who led the study, explained: «Our team has identified that this new syndrome is caused by a small deletion on chromosome 6 that affects the function of hypothalamus, a region of the brain that plays a number of important roles in the body.»

As the rate of children with autism in the U.S. continues to grow, a new study published today in top - ranked journal Pediatrics shows that medical professionals can't rely solely on their clinical judgment to detect autism risk.

Beginning with the Nazi Doctors» Trial at the 1946 Nuremberg Trial (1), coverage includes publication of Henry Beecher's «Ethics and Clinical Research» (2), The New York Times exposure of the public health service syphilis study in Macon County, Alabama (the infamous «Tuskeegee case»)(3), the University of Pennsylvania / Gelsinger gene transfer case, and The Washington Post series on international clinical drug testing abuClinical Research» (2), The New York Times exposure of the public health service syphilis study in Macon County, Alabama (the infamous «Tuskeegee case»)(3), the University of Pennsylvania / Gelsinger gene transfer case, and The Washington Post series on international clinical drug testing abuclinical drug testing abuses (4).

Indeed, this study shows that the therapeutic efficacy of a new drug that is currently in clinical trial depends on Sestrin1.

The new study, published March 14 in the Journal of Clinical Investigation, focused on a particularly aggressive form of B - cell acute lymphoblastic leukemia (B - ALL), the most prevalent type of leukemia in children and young adults.

«Our work represents a unique intersection between the fields of biology and engineering that allowed for entirely new investigational strategies applied to the study of clinical disease,» says Animesh A. Sinha, MD, PhD, Rita M. and Ralph T. Behling Professor and chair of the Department of Dermatology in the UB School of Medicine and Biomedical Sciences and senior author on the study.

The new study, based on recordings from the brains of 37 patients fitted with NeuroPace implants, confirmed previous clinical and research observations of daily cycles in patients» seizure risk, explaining why many patients tend to experience seizures at the same time of day.

The white paper recommends that practitioners follow relevant guidance documents and that deviation from consensus recommendations should be supported by clinical studies or pursued in the setting of a clinical trial approved by an institutional review board; that practitioners receive training in a new procedure before beginning its practice, that the training should include a practical, «hands - on» component and that all team members directly involved with the radiation therapy decisions should participate in at least five proctored cases before performing similar procedures independently; and that professional societies should accelerate the generation of new or updated guidance documents for the following disease sites and techniques: skin, central nervous system, gastrointestinal, lung or endobronchial and esophagus, and, while outside the charge of this panel, assess the need for updated guidance documents for accelerated partial breast irradiation using electronic brachytherapy.

Co-author Julia C. Basso, PhD, post-doctoral research fellow, Center for Neural Science at New York University, commented, «The studies presented in this review clearly demonstrate that acute exercise has profound effects on brain chemistry and physiology, which has important implications for cognitive enhancements in healthy populations and symptom remediation in clinical populations.»

«In this study, a new «source analysis» method was used for the first time to measure functional networks in the infant brain: with the help of a computer model, the measured EEG signals were interpreted as activity in the infant cortex, which enabled the evaluation of the functional networking of neurons in a very versatile manner on the cortical level,» says Sampsa Vanhatalo, a professor in clinical neurophysiology and the head of the study.

The researchers designed the study, called Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Coronary Artery Bypass Grafting Surgery (ERICCA), in an effort to find new ways to improve bypass outcomes for high - risk patients.

TORONTO, May 12, 2016 — A new Canadian study focusing on caregiver outcomes of critically ill patients reveals that caregivers of intensive care unit (ICU) survivors, who have received mechanical ventilation for a minimum of seven days, are at a high risk of developing clinical depression persisting up to one year after discharge.

This research, published today in the online journal PLOS ONE, builds on the 2010 Global iPrEx clinical study, which reported that Truvada, an FDA - approved drug used for years to treat HIV - positive patients, could also prevent new infections in people likely to come in contact with the virus.

Based on proof - of - concept pre-clinical studies indicating robust efficacy and favorable safety profile, the company is now advancing to conduct a clinical trial testing the efficacy of this new treatment.

Emphasis is on clinical research, but recently we initiated pre-clinical studies to pilot new interventions and to enhance our understanding of tretament processes.

In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.

Biological and clinical follow - up studies on known and new genes will improve understanding of the causes of RA, and allow for better risk assessment in Arabs and opportunities to develop new RA therapies.»

Research ranges from basic molecular and genetic studies to epidemiological and clinical research on cancer prevention, early diagnosis, molecular characteristics of the cancer process and new treatments for cancer using drugs and radiotherapy.

In a substudy, review outcomes were also compared across different types of clinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanClinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanclinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human tissue.

A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer.

The positive results from the two phase III studies of ipilimumab were made possible in part through the evolution of the clinical science, which is based on new models of academic - industry partnership to advance immunotherapy development.

The first - of - its - kind study found the dual treatments to be safe and elicit a clinical response in patients, according to new results from a phase I trial to be presented at the AACR Annual Meeting 2015 on Sunday, April 19 (Abstract #CT137).

Antibodies to a high - risk type of human papillomavirus (HPV16) could help detect oropharyngeal (1) cancer several years before the clinical onset of the disease, reveals a new study from the International Agency for Research on Cancer (IARC) in cooperation with the German Cancer Research Center (DKFZ) and the United States National Cancer Institute (NCI) in an article published online today by the Journal of Clinical Oclinical onset of the disease, reveals a new study from the International Agency for Research on Cancer (IARC) in cooperation with the German Cancer Research Center (DKFZ) and the United States National Cancer Institute (NCI) in an article published online today by the Journal of Clinical OClinical Oncology.

A new study from The American Journal of Clinical Nutrition found that overweight men who were on a high - protein diet gained 3 pounds of muscle and lost 11 or 12 pounds of fat.

â $ I canâ $ ™ t say I am aware of any major studies in the literature exploring topical application of eggshell membrane on collagen formation or inflammation in the skin, â $ says Dr. Julia Tzu, clinical assistant professor of dermatology from New York University.

«There's really not much scientific studies on the use of kukui oil in the dermatologic literature, and the one study I know of failed to demonstrate any differences between kukui oil and the placebo in treating mild psoriasis,» says Julia Tzu, MD, clinical assistant professor of dermatology at New York University School of Medicine.

Your overworked doctor barely has time to scan the abstracts of the New England Journal of Medicine every month, let alone dig deeply into the hundreds of studies that are published every year on vitamins and nutrients in journals such as the American Journal of Clinical Nutrition.

She studied to earn her Master Herbalist Certificate and then went on to study nutrition more in - depth, earning her Master's Degree in Applied Clinical Nutrition from New York Chiropractic College, Advanced Nutrition Response Testing ℠ Certificate, and practicing Nutrition, Herbalism, and Nutrition Response Testing ℠.

This revolutionary study on the new delivery form of HMB has now resulted in several clinical studies showing safety and efficacy.

Research has continued to be one of her passions, as she has studied ethnobotanical medicine and edible plants used in the Mediterranean diet for Diabetes through a doctoral program at The University of Lancaster in the UK and did a clinical study on the traditional Mediterranean diet at her practice in New Haven, CT..

By taking a high - cost drug with a low - fat meal — instead of on an empty stomach, as prescribed — prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).