Sentences with phrase «on phenotypic change»

This suggests that for the most part the accumulation of DNA gains and losses have had little impact on phenotypic change.

Not exact matches

At present, and based on what we know of the genetic regulation of development, these phenotypic changes in the gut are most likely the result of positive genetic changes in the genetic regulatory pathways controlling the development of the relevant anatomical features, i.e. they are novel positive, heritable genetic features producing a specific and functional novel anatomical structure within the Genus.
Zachariah Gezon, a Ph.D. student in Ecology and Evolutionary Biology at Dartmouth College, studied the impact of early snow removal on a native mustard plant as part of a study looking at climate change and phenotypic plasticity.
The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.
The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a specific health issue even though they have a SNP mutation.
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