In what concerns intra-membrane constituents, the focus of interest has been
on phosphatidylinositol lipids and their capacity to orchestrate endocytic events on the cytosolic leaflet of the membrane.
Not exact matches
Research in the Emerling Lab is focused
on phosphoinositide signaling, in particular the role of the
phosphatidylinositol -5-phosphate 4 - kinases (PI5P4Ks) in cancer metabolism.
Association of
phosphatidylinositol 3 - kinase with a specific sequence of the T cell receptor zeta chain is dependent
on T cell activation.
This, in turn, is actually a lipid kinase and it phosphorylates lipids
on the plasma membrane, making a new or synthesizing a new phosphate or a lipid
phosphatidylinositol lipid called PIP - 3.
The
phosphatidylinositol pathway,
on the other hand, is triggered by the Gq - coupled receptors.
Fatty acids differentially influence
phosphatidylinositol 3 - kinase signal transduction in endothelial cells: impact
on adhesion and apoptosis.