Sentences with phrase «on plasma cells»

Beta -2-microglobulin is a protein found on plasma cells.

Not exact matches

The new findings build on prior research from the Dhodapkar lab demonstrating that patients with Gaucher disease, an inherited lipid storage disorder, have a significant increased risk for developing myeloma; and the discovery of a subset of lipid - reactive immune cells, called type II NKT - TFH, that promote the development of plasma cells.

The method relies on a special dye that shows up brown when mixed with whole blood, but turns teal when mixed with plasma that has been separated from red blood cells.

If the red blood cells clump, only the plasma will make it through, causing the dye to turn teal and indicating that the corresponding marker (A on the left and B on the right) is present.

Ringer's lactate solution (Lactec) was irradiated with plasma for 3 - 5 minutes, after which it demonstrated anti-tumor effects on brain tumor cells.

The plasma membrane works between the machinery on the inside of the cell and the outside fluid that bathes the cells.

Current treatment strategies focus on the rapid delivery of red blood cells, plasma and other clotting products.

It has been found that the establishment and maintenance of polarity is governed by the interdependent relationship between the polarity marker protein on the plasma membrane (cell membrane), actin, the microtubule cytoskeleton, and membrane vesicle transport.

In the final step in bacterial cell division, constriction of the so - called Z - ring, an annular structure that forms on the plasma membrane near the midpoint of the cell, gives rise to the two daughter cells: A research team led by Erwin Frey, who holds the Chair of Statistical and Biological Physics at LMU, has now used mathematical modelling to understand the mechanism that drives formation of the Z - ring, and in so doing have uncovered a novel class of pattern - forming mechanism in biological systems.

Although myeloma is, like leukemias and lymphomas, a cancer involving white blood cells known as lymphocytes, myeloma cells don't traditionally express CD19 on their surface because they arise from the most mature type of lymphocytes — plasma cells.

With the holiday season officially upon us, the hunt is on for the hottest cell phones, flat - screen plasma TVs and video game systems.

Unfolded proteins create stress on the cell, and you potentially create situations where you now put less assembled proteins in the plasma membrane.

The strategy of giving a higher proportion of plasma is based on the belief that maintaining the balance of coagulation factors carried in plasma would reduce the overall amount of bleeding, requiring lower amounts of red blood cells and improving survival.

The article Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization was published in the journal Nature Communications on September 6, 2016.

CXCR4 - using viruses in plasma and peripheral blood mononuclear cells during primary HIV - 1 infection and impact on disease progression.

The study focuses on the discovery, confirmation and validation of novel biomarkers in a non-interventional manner applying NGS, multiplex PCR and miRNA technologies to determine the biomarkers according to free circulating DNA, RNA, miRNA of maternal plasma, serum and white blood cells along with the use of extracellular vesicles.

Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascular Cell Biology and Director of the Proteomics Core at Joslin Diabetes Center and an Associate Professor of Medicine at Harvard Medical School, now has shown that a substantial percentage of patients with DME do not have high levels of VEGF in the fluid inside their eyes but do have high levels of a protein called PKal (plasma kallikrein) and associated molecules that are key players in an inflammatory molecular pathway involved in the disease.

Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma - membrane - targeted Rab5 on clathrin - dependent endocytosis.

«All this time infected people are taking the drugs and we don't see any virus in the plasma, but actually the virus is hiding in the cells,» said Gupta, senior author on the study and vice chair of the department of infectious diseases and microbiology at the University of Pittsburg.

Differential evanescence nanometry: live - cell fluorescence measurements with 10 - nm axial resolution on the plasma membrane.

You can also register for our webinar on genomic analysis of plasma cell - free DNA, which is coming up on April 10 and features Dr. Geoffrey R. Oxnard.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

Frequencies of IgG1 + plasma cell are shown in plots (right panels) pre-gated on Hy10 plasma cells.

The TruePrime ™ Necrotic cell - free / exosomal DNA amplification kit uses a novel multiple displacement amplification method based on the combination of the recently discovered DNA primase TthPrimPol, and the highly processive and high - fidelity Phi29 DNA polymerase, to amplify genomic DNA starting from cell - free DNA * obtained from plasma, serum, urine or any other bodily fluid.

On arrival, the samples were centrifuged (1200 × g, 15 min, room temperature) to separate plasma from buffy coat and red blood cells, and the samples were frozen in liquid nitrogen until they were analyzed.

Fasting blood samples were processed on the same day for serum lipids, plasma glucose concentrations, white blood cell (WBC) count, and fibrinogen by the Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, Australia.

In other words, increasing plasma GSH by supplementing with whey protein may not necessarily have the desired effect on the appropriate brain cells and tissues.

In this prospective, open and non-randomized study, the effect of alpha - lipoic acid on the progression of endothelial cell damage and the course of diabetic nephropathy, as assessed by measurement of plasma thrombomodulin and urinary albumin concentration (UAC), was evaluated in 84 patients with diabetes mellitus over 18 months.

As one of the Best Orthopedic Surgeons in Beverly HIlls and Los Angeles CA, Dr. Raj provides the ultimate in state - of - the - art quality orthopedic care available and is always on the cutting edge of the latest surgical and nonsurgical technologies such as PRP (Platelet Rich Plasma) injections, stem cell injections for tendonitis and arthritis, minimally invasive surgery and more.

Sandstead, H. H., Prasad, A. S., Penland, J. G., Beck, F. W., Kaplan, J., Egger, N. G., Alcock, N. W., Carroll, R. M., Ramanujam, V. M., Dayal, H. H., Rocco, C. D., Plotkin, R. A., and Zavaleta, A. N. Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteins.

The release of enteroglucagon was not due to delayed absorption in the guts of rats fed guar gum because the ingestion of hydroxypropyl methylcellulose, a viscous nonfermentable polysaccharide, had no effect on plasma enteroglucagon concentrations or on ileal crypt cell size (Gee et al. 1996).

In short, I suspect The Cell 2 was never meant to be up there on my plasma, where all its obvious shortcomings are as clear as that zit on your nose.

Animals with plasma cell tumors on the skin do not show signs of illness.

Oral plasma cell tumors are usually on the lips and gums and are similar in size to those in the skin.

In vomiting dogs the initial approach is to distinguish self - limiting from more severe causes of vomiting on the basis of physical fi ndings and a minimum database (e.g. Packed cell volume, total protein, azostick, urinalysis, plasma concentrations of sodium and potassium).

A partial list of the specialized medical procedures and equipment required includes canine and feline red blood cell and plasma transfusion products, central venous catheters, chest tubes, on - site laboratory equipment, analgesia, advanced surgical instruments, ultrasound, endoscopy, and much more.

She has published journal articles and book chapters on topics including canine osteosarcoma, canine and feline liver tumors, and canine and feline plasma cell cancer / multiple myeloma.

Lab Technician II — TRL Plasma Laboratories — January 2013 — Present • Monitor the heat sealing and aseptic sampling of plasma units; place units of plasma into freezer in timely manner in order to ensure quality of product • Label plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical Plasma Laboratories — January 2013 — Present • Monitor the heat sealing and aseptic sampling of plasma units; place units of plasma into freezer in timely manner in order to ensure quality of product • Label plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical plasma units; place units of plasma into freezer in timely manner in order to ensure quality of product • Label plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical plasma into freezer in timely manner in order to ensure quality of product • Label plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical plasma samples and units properly and store according to policy; manage an average of 50 different plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical plasma units on a regular basis • Evaluate refrigerator and freezer temperatures ad inform supervisor if equipment is malfunctioning • Maintain efficient and clean work environment and ensure inventory is stocked properly; answer phones and answer questions or transfer calls to appropriate departmentLab Technician I — ABC Medical Technologies, Inc. — May 2007 — January 2013 • Operated laboratory equipment, such as cell counters and microscopes, to analyze urine, blood, and tissue samples; recorded both normal and abnormal findings; had less than a.1 percent margin of error in sample findings • Used computerized instruments and automated equipment to perform multiple tests at one time; maintained calibration and proper function of equipment on a regular basis • Entered data from tests into physician reports; discussed abnormal results with supervisor and re-ran tests before logging data into patient's medical record

Effects of Storage Duration and Temperature of Human Plasma and Serum on Red Blood Cell Aggregation and Shape

Direct and indirect effects of genetic and nutrition (including maternal diet) on AD with PUFA in buccal cells and plasma glycerophospholipids as a potential mediator will be evaluated by moderated mediation path analysis.50