Sentences with phrase «on populations of cells»

In a sort of molecular «Where's Waldo,» scientists are often left with no choice but to measure a disease's effects on populations of cells, rather than a single cell.

«Young students of cognitive neuroscience are lucky to be in the midst of a new era where we have access to amazing new tools of science for eavesdropping on the population of cells with a superb temporal resolution,» Parvizi says.

Not exact matches

(i) a woman's right to choose; (ii) teaching evolution in school; (iii) medical immunization of teen girls against HPV; (iv) assisted suicide; (v) gay marriage; (vi) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» by theists (vii) basic $ ex education for older school children; (viii) treating drug abuse as principally a medical issue; (xi) population control; (x) buying alcohol on a Sunday; (xi) use of condoms and other contraceptives (xii) stem cell research.

And with 7billion on the planet (and growing), these «young people missing millions from their generation» should be thankful that clusters of cells can be medically removed, preventing unwanted births and (perhaps) even saving the human population from growing to a point of unsustainability.

In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.

(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education for older school children; (ix) treating drug abuse as principally a medical issue; (x) population control; (xi) buying alcohol on a Sunday in many places; (xii) use of condoms and other contraceptives; (xiii) embryonic stem cell research; (xiv) little 10 year - old boys joining organizations such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly in the military.

Tunisia's 10 million residents and two million expatriate citizens are avid users of technology, however: 85 % of the population has cell phones (5 % smart phones), and roughly two million of them are on Facebook.

The design features a central viewing chamber with a system of mirrors that allows a single guard to keep watch on the entire prison population in their cells.

Campaign staff also relied on cell phones to reach segments of the population less likely to be on a computer regularly, such as young people, minorities and the poor.

However, the MIT team adapted it to randomly turn on or off distinct gene sets across large populations of cells, allowing the researchers to identify genes that protect cells from a protein associated with Parkinson's disease.

This allows us to reveal how drugs affect heart functions in a scenario where the two cell populations are closely coupled,» said Ben Maoz, Ph.D., a co-first author on the second study, who also is a Technology Development Fellow at the Wyss Institute and a member of Parker's group.

In this study, the researchers found that a specific population of immune cells called macrophages have the ability to secrete or produce a protective or healing factor known as Interleukin - 10 (IL - 10), which can interact with receptors on intestinal epithelial cells to promote wound healing.

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

By using these and other high - tech tools, the researchers homed in on a unique population of T - cells that are highly prevalent in the joints of rheumatoid arthritis patients.

Saatchi, which is owned by France's Publicis Groupe, SA, chose LifeStraw over a field of competitors that included a reusable controller to improve the distribution of IV fluids, a collapsible wheel that can be folded down for easier storage when not in use on bicycles or wheelchairs, an energy - efficient laptop designed for children in developing countries, a 3 - D display that uses special optics and software to project a hologramlike image of patient anatomy for cancer treatment, an inkjet printing system for fabricating tissue scaffolds on which cells can be grown, a visual prosthesis for bypassing a diseased or damaged eye and sending signals directly to the brain, books with embedded sound tracks to help educate illiterate adults on health issues, a phone that provides telecommunications coverage to poor rural populations in developing countries, and a brain - computer interface designed to help paralyzed people communicate via neural signals.

They then examined genetic variants throughout the human genome for their effects on gene expression in these two representative populations of immune cells.

Next steps include examining whether the viral infections play a role in controlling the population of toxic algae and continued studies on the nutrients these cells use to grow.

Professor Gianni Liti, a senior author on the paper from the Institute for Research on Cancer and Ageing, Nice, said: «We were able to study the evolution in time by combining genome sequences of the cell populations and tracking the growth characteristics of the yeast cells.

They might also come up with a way to select the right cells out of a mixed population; Anand Swaroop, an ophthalmology researcher at the University of Michigan at Ann Arbor, is working on a way to identify and weed out the photoreceptor cells by focusing on proteins present on cell surfaces.

Lee hopes the work will allow other researchers to investigate the effects of transfection on individual cells, not just large populations.

The study introduced here focused on a population of support cells in the spinal cord that helps to protect surviving nerve cells (neurons) after injury: oligodendrocytes and their precursor cells.

A couple of other research groups have also sorted stem cells based on gene expression, but they have not done so specifically with the goal of enriching cell populations for a specific tissue, the researchers said.

«Computer - based classification of cells based on large population of cell images opens up new perspectives.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

Now a team of engineers at MIT has developed a new way to deliver such vaccines directly to the lymph nodes, where huge populations of immune cells reside: These vaccines hitch a ride to the lymph nodes by latching on to the protein albumin, found in the bloodstream.

Although their function is not completely understood, a special population of cells covering the blood vessels on the brain's surface is thought to contribute to the organ's protection.

The code that a monkey's brain uses to represent faces relies not on groups of nerve cells tuned to specific faces — as has been previously proposed — but on a population of about 200 cells that code for different sets of facial characteristics.

In addition, they also counted the numbers of various types of single - celled organisms called testate amoebae, whose population changes depending on the amount of water in the bog, giving an indication of how wet or dry the climate was during different periods.

To identify this T cell population, the researchers took biopsies at the sites of active lesions before treatment and biopsies of the same skin areas after the lesions had cleared on therapy.

It's been challenging to zoom in on the population of T cells driving the disease in part because when psoriasis is active, lesions are flooded with diverse T cells.

In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells.»

Most of the cells that made up the tumors were positive for CA125, but the researchers found a small population that were negative and focused on those, Janzen said.

However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.

What's really impressive about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate research programs.

«We have discovered that by timing the inhibition of STAT3 — like an «on / off» light switch — we can transiently expand the satellite - cell population followed by their differentiation into mature muscle cells.»

They have detected, for example, revved up signaling molecules involved in inflammation, such as tumor necrosis factor α (TNFα) and other cytokines; skewed populations of natural killer cells and other immune cells; imbalances in the protein - destroying enzymes called proteases; and a shortening of the telomeres, the «end caps» on chromosomes, which indicates prematurely aged cells.

To look at the effects of heat shock on native populations of proteins, Drummond and his colleagues utilized a novel set of techniques that allowed them to simultaneously track almost 1,000 different mature proteins in yeast cells.

This year, the number of mobile phones on cell networks is expected to surpass the Earth's population.

«We have identified two new populations of cells in the brain that potently regulate appetite,» says Alexander Nectow, first author of the paper, published in Cell on July 27.

The second branch of the combination therapy, the low - dose metronomic chemotherapy, was similarly found to exert its therapeutic effect through a novel, hitherto unrecognized mechanism: The metronomic chemotherapy turned out to not primarily target the tumor cells, but to act on the recruitment of yet another tumor - promoting cell population from the bone marrow.

The researchers tested the drug on mice with H. pylori infections from several different cell lines, and found that the drug was effective against the H. pylori while maintaining populations of healthy gut bacteria.

Western Pygmies I love population genetics for its ability to peer back into human history through the medium of DNA's ATCGs.One of the stars of this discipline is Sarah Tishkoff, a standout in African genetics, someone who will readily haul a centrifuge into the bush in Cameroon.Tishkoff of the University of Pennsylvania is lead author on a paper published online July 26 in Cell that details whole - genome sequencing of five individuals each from three extant hunter - gatherer groups — the Pygmies of Cameroon as well as the Hadza and the Sandawe of Tanzania.

The new study from Tonegawa's group builds on previous research demonstrating that episodic memories are physically represented in populations of cells in parts of the hippocampus.

To devise a potential new therapy, the investigators engineered a population of neural stem cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates cell - death - inducing receptors found only on the surface of cancer cells.

Thus, our selection strategies, which were based on targeting endothelial populations that expressed both of these inducible glycoproteins, suggest that the endothelial cell lines generated in this study are most likely from this microcirculatory region.

The team used a combination of experiments to zero in on the molecular activity of melittin at the «minimal inhibitory concentration» (MIC), the lowest concentration that's been shown to slow the growth of target cell populations.

Other forms of cell - cell interaction, on the other hand, are only effective in mixed population structures; these include, for example, cross-feeding mutualisms in which different cell types depend on close proximity to benefit each other [17 — 19].

But the new study firmly establishes that some of these cells endure for many decades in some Medalists — offering clues to potential treatments for preserving and even restoring the crucial cell population, says George L. King, M.D., senior author on the paper, Joslin's chief scientific officer and head of the Dianne Nunnally Hoppes Laboratory for Diabetes Complications.

Since secreted enzymes can be costly to produce and may benefit all cells in the immediate surroundings, their evolutionary stability often relies on population structure, which can promote preferential interaction among cells of a single strain.

Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etCell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etcell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etcell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).