Not exact matches
Portions of the case file, including documents about marketing of the
drug and Purdue's attempts to ward off limits
on prescribing, remained sealed until STAT filed a motion in May to open the records.
Physicians
prescribe medical foods, but they are less tightly regulated than
drugs and normally don't require large trials, which means the stuff could be
on the market as soon as this year.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS
Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the S
Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new
drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the S
drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to
prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
After a brief lag, the
drug is now being
prescribed at the rate of at least 10,000 scripts a day, outpacing such famous quick starters as the antidepressant Prozac (which went
on to become one of the biggest - selling
drugs in America) and the baldness remedy Rogaine (which has been something of a disappointment after its initial blaze of popularity).
Valeant
Prescribed drugs (VRX) plummeted almost seventeen % after Congressional Democrats pushed to subpoena the organization above current value hikes
on two coronary heart
drugs.
Large companies (Big Pharma) spend considerable amounts
on advertising and distribution, and often have large sales forces that promote their
drugs to physicians to convince them to
prescribe the
drug.
A doctor
prescribed me Prozac and that worked quite well but I didn't like the idea of being
on a
drug that affected my brain, so I stopped.
A number of medications should be avoided while breastfeeding, including
drugs prescribed to kill cancer cells, radioactive drugs and illicit drugs, according to the American Academy of Pediatrics» Committee on D
drugs prescribed to kill cancer cells, radioactive
drugs and illicit drugs, according to the American Academy of Pediatrics» Committee on D
drugs and illicit
drugs, according to the American Academy of Pediatrics» Committee on D
drugs, according to the American Academy of Pediatrics» Committee
on DrugsDrugs.
Most
drugs likely to be
prescribed to the nursing mother should have no effect
on milk supply or
on infant well - being.
The IBCLC does not have prescriptive power, so can not
prescribe herbs or medication, but she can educate families
on their options for herbal or medicinal support with lactation, as well as
drug interactions of other
prescribed medications.
The antibiotic
prescribed will depend
on your specific situation, your doctor's preference, and any
drug allergies you may have.
Teens with lupus should take their
prescribed medication
on time, take frequent breaks to avoid getting fatigued and avoid alcohol, cigarettes and
drugs.
Bill Hammond, a health policy analyst with the fiscal watchdog group the Empire Center, agreed that the tax would likely be passed
on to patients who need the
drugs, including terminally ill people and patients with chronic conditions, as well as addicts who are sometimes
prescribed medicines that contain a form of opioid.
Access to the New York State Medicaid Data Warehouse gives Erie County real - time information
on Medicaid activity, such as the most commonly
prescribed drugs for Medicaid patients.
«Hydrocodone / oxycontin is the number one
prescribed drug for those who are
on medicaid, and it's not even close to what the second
drug is.
It's probably the number one
prescribed drug to those who are
on private pay insurance companies as well,» said County Executive Mark Poloncarz, D - Erie County.
From holding educational seminars for doctors
on proper opioid
prescribing practices to training first responders and community members in the administration of Narcan, the members of our health department are working very hard to save lives and prevent others from becoming addicted to these
drugs.
Republican Senate Majority Leader John Flanagan
on Tuesday said it was unlikely a bill that would allow doctor to
prescribe life - ending
drugs to terminally ill patients would be considered by his chamber.
But GPs must concentrate more
on following official guidelines, increasing the
prescribing of generic
drugs where clinically appropriate,» committee chairman Edward Leigh said.
Even though Obama said in 2008 that he considered the «basic concept of using medical marijuana for the same purposes and with the same controls as other
drugs prescribed by doctors... entirely appropriate» and did not plan
on using the DOJ's resources to circumvent state laws, the department has continued to raid, and in some cases shut down, dispensaries and cultivation facilities in at least nine state since he took office.
Bill Hammond, a health policy analyst with the fiscal watchdog group the Empire Center agrees that the tax would likely be passed
on to patients who need the
drugs, including terminally ill people and patients with chronic conditions, as well as addicts who are sometimes
prescribed medicines that contain a form of an opioid.
So I would say, based
on what was
prescribed to Medicaid patients in Erie County, it wouldn't shock me if
on an annual basis more than 10 million pills of these related
drugs were
prescribed annually.»
The Opioid Epidemic [May 10, 2017] Opioid addiction has reached epidemic proportions in the United States, with overdoses and deaths caused by
prescribed and «street»
drugs on the rise.
Blaser, director of New York University's Human Microbiome Program, presents a sensible plan for reclaiming our microbial balance and avoiding calamity both as a society — he calls for an overhaul of how
drugs are
prescribed — and
on an individual level.
By taking a high - cost
drug with a low - fat meal — instead of
on an empty stomach, as
prescribed — prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).
Gomes said there are several potential explanations for the provincial differences in high - dose opioid
prescribing, including varying coverage among public
drug plans, training among prescribers and differential marketing
on the part of pharmaceutical companies.
NEW ORLEANS — A long - awaited study
on painkillers called nonsteroidal anti-inflammatory
drugs, the most widely
prescribed class of
drugs in the world, has concluded that the three most commonly used carry a similar risk of cardiovascular complications.
Austad says other medications have shown similar effects
on extending mouse life span, including acarbose (a common
drug prescribed for Type 2 diabetes), and anti-inflammatory
drugs such as masoprocol and basic aspirin.
Crockett points out that antidepressants are the most widely
prescribed class of
drugs in the US and that it is therefore important to investigate their effects
on users» social behaviour and moral judgement.
While flibanserin may not ever be
prescribed for sexual dysfunction — and there is much debate over whether the «dysfunction» it targets is real or just marketing — the
drug does show modern neuroscience's broader and deeper effects
on our minds.
Through the FDA's iPLEDGE program, woman who are
prescribed the
drug must pledge to use two forms of contraception, in addition to taking regular pregnancy tests while
on the
drug and online tests to make sure they understand the dangers of getting pregnant while taking the
drug.
But the same
drugs, whether
prescribed by a doctor or bought
on the street, can quickly turn deadly by simultaneously messing with crucial systems in the body.
A clinician and expert
on herb -
drug interactions, Fugh - Berman thought the information could be useful to clinicians who
prescribe warfarin as an anticoagulant.
«As physicians, we are often so focused
on knowing which
drug to
prescribe or which test to order that we overlook the fact that many patients fail to get follow - up care to begin with,» Ko said.
If 40 percent of MSM who are good candidates for PrEP based
on CDC's guidelines were actually
prescribed the
drug and used it consistently, 33 percent of new HIV infections in this population in the U.S. would be avoided over the next 10 years, the researchers found.
Historically, Loyola physicians have not
prescribed rapamycin - class
drugs to LAM patients who are
on the waiting list for lung transplants.
On the other hand, if doctors
prescribe a
drug that was not requested by the patient, they are ambivalent about it just 12 percent of the time.
If you believe the headlines, this is terrible news, and people stand to miss out
on treatments for disorders ranging from pain and depression to osteoarthritis and cancer, because the National Health Service will no longer
prescribe the
drugs.
The
drug is
prescribed for severe pain, but is increasingly being sold
on the street, often mixed with heroine or other
drugs.
«We are using CYP2C19 genetic testing
on a daily basis at our institution to help decide in a timely manner which
drug to
prescribe,» said George «Rick» Stouffer, III, M.D., F.A.H.A., chief of cardiology and co-director of the McAllister Heart Institute at UNC.
«Since 95 percent of cancer patients still get chemo, we realized we could make a major impact
on cancer treatment by helping clinicians
prescribe the right chemotherapy
drug,» said Sourav Bandyopadhyay, PhD, a professor of bioengineering and therapeutic sciences in UCSF's Schools of Pharmacy and Medicine and senior author
on the new study.
... One way to cut down
on drug resistance transfer is to stop
prescribing antibiotics almost...
The more information researchers gather, the greater opportunity clinicians will have
prescribed the
drug that is most efficacious based
on the patient's specific mutation.
New research
on opioid
prescribing in Washington State reports that a health plan initiative to change shared expectations of physicians regarding clinically appropriate
drug levels for long - term management of chronic pain achieved significantly greater reductions in opioid dosing.
Around the turn of the century, though, researchers noticed that women
on HRT had an increased risk of heart disease, uterine and breast cancers, and strokes, and doctors generally stopped
prescribing the
drugs.
The U.S.
Drug Enforcement Administration startled many marijuana proponents last month when it placed Syndros
on Schedule II of the Controlled Substances Act, making it federally legal to
prescribe.
«Sleeping pills are most often last
on the list of
drugs prescribed,» Lecomte says.
Moreover, health - policy experts must script guidelines
on how to
prescribe it, and how to monitor side effects and HIV infections in people using the
drug.
One of the quirks of
prescribing practice in France is that
on average doctors
prescribe 3.2
drugs on each prescription form, which is about one more than in the three other European countries in the CREDES study.
«Eliminating cost barriers helps heart patients comply with
drug regimens: Study
on drug adherence provides insights
on prescribing patterns and clinical outcomes.»