Sentences with phrase «on signal transduction»
Programs with research emphasis on signal transduction in development and oncogenesis, cell adhesion molecules in development and oncogenesis, muscologskeletal atrophy and countermeasures, ovarian follicle development, neural regeneration, implantable therapeutic or diagnostic devices and application of computers in veterinary education.
https://vet.purdue.edu/
Molecular mechanisms of heart failure and arrhythmogenesis with focus on signal transduction
In 1995, I began graduate studies on signal transduction by growth factors and receptor tyrosine kinases in the laboratory of Graeme Guy at the Institute of Molecular and Cell Biology (IMCB) in Singapore, obtaining my PhD in 2000.
The restructured program's dozen research groups, Karsenti says, will focus on signal transduction, the cytoskeleton, and membrane trafficking.
Not exact matches
In addition to authoritative insights and collections of reviews, features, and News Focus articles in Science, Science's Signal Transduction Knowledge Environment and the Science of Aging Knowledge Environment will offer special content on drug discovery.
His graduate and postdoctoral work led to seven first author papers in the Journal of Biological Chemistry, including four back - to - back papers on fundamental characterization of arachidonic acid pathways, and a Cell paper, which was the first to demonstrate cAMP - independent G protein participation in receptor - mediated signal transduction.
We are focusing on a few key molecular pathways including; 1) Polycomb - mediated epigenetic gene silencing in the tumor initiation, maintenance, and invasion, 2) c - Met (receptor tyrosine kinase) signal transduction pathways in stemness and migration of these tumor cells, 3) Novel mitogenic signaling pathways that are specific to GSCs, and 4) Identification of radio - and chemo - sensitizing pathway to maximize therapeutic efficacy.
Dr. Levitsky: Other sections under the Oncology Discovery and Translation Area (DTA) focus on anti-angiogenesis, small molecule inhibitors of the p53 pathway, apoptosis, signal transduction, and the tumor microenvironment.
His academic research focused on gene regulation and signal transduction mediated by ion channels and G proteins.
Aside of the inhibition of signal transduction, on - target repositioning assumes that the targets recognized in nematods, such as mitochondrial respiration and microtubules, are hit in cancer cells [70, 89, 90].
Murat completed his PhD at NCSU focusing on systems biology of growth factor - mediated signal transduction pathways.
Sophie Jarriault did her PhD on the transduction of the Notch signal in mammals in Alain Israël laboratory at the Pasteur Institute, Paris.
On the one hand, we developed light - switchable compounds as tools for interrogating the dynamics of signal transduction in cells.
Given the predominant role for DAG on regulating Ras / Erk and PKC - θ signaling and Cbl - b for regulating PI (3) K signaling, we hypothesized that T cells deficient in DGKζ or Cbl - b would alter TCR signal transduction through distinct mechanisms, such that DGKζ - deficient T cells would demonstrate strongly enhanced Ras / ERK activation, but only modestly enhanced NF - κB activation, and Cbl - b — deficient T cells would demonstrate modestly enhanced Ras / ERK activation and strongly enhanced NF - κB activation.
She did her PhD on the transduction of the Notch signal in mammals in Alain Israël laboratory at the Pasteur Institute, Paris; she realised her postdoc with Iva Greenwald, at Columbia University NYC, on vulva organogenesis in C. elegans.
The current project will use high - resolution mass spectrometry - based metabolomics approaches to measure temporal and spatial changes of metabolic pathways in the RPE and retina under both physiological and disease conditions, with a focus on mTOR - mediated signal transduction pathways.
Klemke, Wang, and their colleagues are involved in research on aspects of the basic biology behind metastasis — trying to identify the signal transduction mechanisms that lead to the spread of breast cancer cells.
These chains are present on the cell surface and are crucial for many biological processes, including cell adhesion and signal transduction.
We study the signal transduction pathways regulating cell growth and proliferation, with an emphasis on kinase enzymes.
Studies of satellite cell activation via nitric oxide have opened an exciting area of research on muscle regeneration, growth and the muscle - fiber cytoskeleton that integrates mechanical and biochemical signal transduction with cell and molecular biology of muscle tissue in growth, development, disease, aging and evolution.
We've been particularly involved in understanding the effects of ethanol on hormone and cytokine receptor - dependent signal transduction.
His laboratory focuses on the roles of reversible protein modifications that are involved in modulating signal transduction, chromatin dynamics and gene activation.
His laboratory is currently focused on characterizing signal transduction pathway abnormalities in prostate cancer, with an eye toward translational implications.
Because Syk is expressed in many kinds of hematopoietic lineage cells and involved in various ITAM - mediated signal transduction pathways (45), our current finding that RhoH facilitates Syk activation will shed new light on ITAM - based immune responses.
Recent studies have shown that ALA has a positive impact on insulin action (via the insulin signal transduction pathway) and muscle glucose transport, especially in people whose insulin function is suboptimal, i.e. have developed insulin resistance.
Fatty acids differentially influence phosphatidylinositol 3 - kinase signal transduction in endothelial cells: impact on adhesion and apoptosis.
About Blog Random remarks on topics from computational biology, signal transduction, neuroscience etc..
About Blog Random remarks on topics from computational biology, signal transduction, neuroscience etc..