In science news around the world, the U.S. Food and Drug Administration (FDA) cracks down
on stem cell labs, Brazil opens one of its largest national reserves to gold and iron mining, and the International Atomic Energy Agency launches a global bank for low - enriched uranium.
Not exact matches
Lab - grown tissues derived from patients»
stem cells may also allow researchers to screen drugs and test their effectiveness
on diseases like cancer.
But the next big question was whether these
cells could home in
on tumors in
lab dishes, and in animals, like neural
stem cells.
Culturing
stem cells by day, and audiences in dingy stand - up clubs by night, it wasn't until Helen Pilcher left the
lab that she started basing her comedy
on science.
Research
on lab animals has shown that the number of hypothalamus
stem cells diminishes with age.
He ruled that work
on existing embryonic
stem cell lines derived outside federally funded
labs did not violate a ban
on the destruction of embryos.
An unusual lawsuit filed last month sheds light
on a scientific misconduct investigation into a prominent cardiac
stem cell lab.
The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal
stem cells using tools developed in the Dick
lab a few years ago to zero in
on specific
cell types fated to relapse.
I couldn't resist composing this after the mention of the charmingly misspelled word «hematopoetic» in your story
on blood grown in the
lab from
stem cells (12 November, p 8):
The problem follows close
on the heels of Hwang's admission that, despite his previous denials, two members of his
lab had donated oocytes for his group's
stem cell experiments and other donors had been paid for their donations (Science, 2 December, p. 1402).
The UK also offers a favorable funding and regulatory climate, says Minger, whose
lab works
on the therapeutic and clinical applications of
stem cell research.
More cautious researchers would have realized they were
on the wrong track, says Rudolf Jaenisch, a
stem cell researcher at the Massachusetts Institute of Technology in Cambridge whose
lab spent 2 months trying to make STAP
cells and contributed data to the new paper.
The researchers used the new
lab -
on - a-chip to study how adult
stem cells in adipose tissue develop into mature fat
cells, conducting their investigations outside the body.
Last May in Nature Neuroscience, his
lab and a team at Columbia University reported that embryonic
stem cells could be used to shed light
on the origins of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease in which motor neurons in the brain die.
To read more in detail about research
on stem cells done in different
labs around the world (the Netherlands, UK, US, and elsewhere) click here.
The Food and Drug Administration approved the trial in January 2009 but put it
on hold last September because of safety concerns after
lab animals injected with
stem cells developed small cysts at the injury site.
Scientists have suggested that such embryonic
stem cells could be used for learning about genetic diseases, testing new drugs
on cells grown in the
lab, or growing healthy
cells for therapeutic transplantation.
Other
labs are already trying to replicate the work, and some have posted their experiences
on a
stem cell blog.
I've still kept my own
lab going focusing
on understanding what pluripotent
stem cells really are, and the extrinsic signals that govern their self - renewal and differentiation.
Zhang
lab Web site Reubinoff
lab Web site PNAS abstract
on getting blood
cells from
stem cells Background
on stem cells, from the National Institutes of Health
«This is essentially a recipe for how to make human inner ears from
stem cells,» said Dr. Koehler, lead author of the study and whose research
lab works
on modeling human development.
A major concern about
stem cells centers
on how unstable they can become when grown in the
lab.
The Humphreys
Lab collaborated with fellow Harvard
Stem Cell Institute member Benjamin Ebert, MD, also at Brigham and Women's Hospital,
on the work.
The Zeng
lab is making great progress
on developing a
stem cell - derived treatment for Parkinson's disease for testing in humans.
Dr. Melton's
lab has been working
on getting «a molecular biography,» he said, of all the genetic steps required to make a
stem cell a beta
cell.
Now, a new
STEM CELLS study from the labs of Qing - Ling Fu (Sun Yat - sen University, Guangzhou) and Zhongquan Qi (Xiamen University, Fujian, PR China) has described the effect of iPSC - MSCs on immune T cells in a relevant in vivo mouse m
CELLS study from the
labs of Qing - Ling Fu (Sun Yat - sen University, Guangzhou) and Zhongquan Qi (Xiamen University, Fujian, PR China) has described the effect of iPSC - MSCs
on immune T
cells in a relevant in vivo mouse m
cells in a relevant in vivo mouse model.
Recently, his
lab used induced pluripotent
stem (iPS)
cells — adult
cells made to act like embryonic
stem cells — made from skin
cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects
on the development, survival, and degeneration of human neurons.
The following questions and answers have been paraphrased from a conversation with Prof. Lorenz Studer
on October 11th, 2017 discussing the
stem cell trials his
lab is set to begin in 2018.
More recently, scientists including Benjamin Spike, a co-first author
on the current work and post-doctoral fellow in the Wahl
lab, have discovered that tumors often contain
cells with
stem cell characteristics revealed by their genetic signatures.
All the projects in the
lab now are focused
on trying to use
stem cells, or other progenitors, to find new treatments for diabetes.
Very interesting article... I find myself amazed at how much work one or two
labs can churn out to advance our understanding — Perhaps you could do a post
on current
Stem Cell centers around the world, and how much man - power and budget is being devoted to them?
The first of this week's review articles from the
lab of Umberto Galderisi (Campania University, Naples, Italy) discusses the effects of low dose ionizing radiation (LDIR)
on the biology of
stem cell compartments.
Our final review article, from the
labs of Maximilian Boesch (Kantonsspital St. Gallen, Switzerland) and Andreas Seeber (Medical University of Innsbruck, Austria), provides an update
on the role of epithelial
cell adhesion molecule (EpCAM) in cancer
stem cells (CSCs) and the epithelial ‐ to ‐ mesenchymal transition (EMT) in colorectal cancer (CRC).
The Ellerby
lab is known for its pioneering studies
on Huntington's disease (HD), and Karen is now using human
stem cell models of HD to understand why important molecular signaling pathways, such as the TGF - β pathway, are dysregulated in HD.
Chunhui Xu's
lab in the Department of Pediatrics recently published a paper in
Stem Cell Reports
on the differentiation of endothelial
cells, which line and maintain blood vessels.
In addition to its emphasis
on producing vaccines, the
lab specializes in gene and
cell therapies, including
stem cell products.
Right now,
stem cell products are commonly produced
on a very small scale to use in
lab experiments, but we need to make them in much greater orders of magnitude for use in future human therapies.
Her
lab focuses
on the regulation and therapeutic potential of blood and muscle
stem cells.
Distilling the most radical accomplishments being made in
labs worldwide, including gene therapy, genetic engineering,
stem cell research, life extension, brain - computer interfaces, and cloning, More Than Human offers an exciting tour of the impact biotechnology will have
on our lives.
Schnabel's research
lab primarily focuses
on equine
stem cell immunology and other regenerative therapies for musculoskeletal injuries and diseases.
Currently, her
lab is focused
on finding drugs suitable for eliminating mammary cancer and ocular herpevirus infections in small companion animals, and evaluating the effectiveness of
stem cell therapies for treating skin wounds in horses — all of which may also be used in humans and other animals.
And meanwhile, university researchers can and do work
on embryonic
stem cells — just so long as they don't use federal funds (which makes for some complicated partitioning of
lab equipment in many a US university department).