Symposia were published, on the glutamate synapse (Neuroscience 2009c), and
on synaptic plasticity and memory (Neuroscience 2009d).
He is one of the world's leading researchers
on synaptic plasticity in the brain and has pioneered new optical methods of observing the structural changes in the living brain as it adapts to its environment.
Not exact matches
Molecular studies of gene expression during long - lasting
synaptic plasticity related to memory storage initially focused
on the identification of positive regulators.
Dr. Stuart Hameroff, lead author
on the new TUS study, said: «This suggests TUS may stimulate natural megahertz resonances in brain microtubules, enhancing not only mood and conscious mental states, but perhaps also microtubule functions in
synaptic plasticity, nerve growth and repair.
A study based
on the research, «Habituation based
synaptic plasticity and organismic learning in a quantum perovskite,» appeared in the August 14 online issue of Nature Communications.
«The new growth rule provides structural
plasticity with a principle that is almost as simple as that of
synaptic plasticity,» says co-author Arjen van Ooyen, who has been working
on models for the development of neural networks for decades.
Mice in booze camp In the new study, performed
on adolescent male mice, ethanol alcohol exposure seemed to enhance
synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.
«Based
on these findings, it was particularly interesting to find out if and to what extent the mGlu5 receptor affects
synaptic plasticity and, consequently, memory formation in the CA3 region,» explains Hagena.
«My lab works
on the neural bases of learning and memory,» says Pozzo - Miller, «so we decided to test if LM22A - 4 was able to improve spatial discrimination deficits by enhancing
synaptic plasticity in the hippocampus, the brain region responsible for spatial learning and memory.»
«Our research shows that combination treatment with the two compounds can promote resilience against stress - mediated depression - like phenotypes by modulating systemic inflammatory responses and brain
synaptic plasticity in a mouse model of depression,» says Jun Wang, PhD, Associate Professor of the Department of Neurology and first author
on the paper.
Professor Martin's research focuses
on the cell biology of transcription - dependent forms of
synaptic plasticity, particularly those underlying learning and memory.
Her research seeks to clarify the protein machinery involved in memory formation and consolidation under normal and pathological conditions, focusing
on synaptic transmission and brain
plasticity.
Based
on evidence from electrophysiological studies showing that both
synaptic plasticity and strength of inputs to hippocampal region CA1 vary systematically with ongoing theta oscillations (Hyman et al., 2003; Brankack et al., 1993), it has been suggested that the theta rhythm functions to separate periods of encoding of current sensory stimuli and retrieval of episodic memory cued by current stimuli so as to avoid interference that would occur if encoding and retrieval were simultaneous.
We continue to focus our efforts
on understanding the distinct roles of the various types of translational control in long - lasting
synaptic plasticity and memory using pharmacological and genetic approaches in various brain regions, including the hippocampus, amygdala, and prefrontal cortex.
Objective: To understand the dynamics and functional roles of
synaptic plasticity in mnemonic phenomena to shed new light
on the cellular bases of learning.
We have previously shown ex-vivo its beneficial effect
on synaptic transmission and
plasticity in a mouse model of the OPHN1 loss of function.Here, we report that chronic treatment in adult mouse with Fasudil, is able to counteract vertical and horizontal hyperactivities, restores recognition memory and limits the brain ventricular dilatation observed in Ophn1 - / y However, deficits in working and spatial memories are partially or not rescued by the treatment.
Mao discovered that nicotine - induced
synaptic plasticity in the VTA is dependent upon one of the drug's usual targets, a receptor for the neurotransmitter acetylcholine located
on the dopamine neurons.