Sentences with phrase «on thalassemia»

Awarded the Royal Medal by the Royal Society for his work on thalassemia; awarded the Fothergillian Prize by the London Medical Society; the Manson Medal by the Royal Society of Tropical Medicine and Hygiene and the Lasker Award.

Not exact matches

bluebird bio (BLUE)- The company's BCMA CAR - T drug candidate bb2121 remains attractive despite overblown fears on durability (peak sales of $ 2 billion or more), LentiGlobin has a good shot at success in TDT (Transfusion - Dependent ß - Thalassemia) and SCD (Severe Sickle Cell Disease), and they have a strong cash position.

Boston Children's Hospital has offered non-exclusive licenses to for - profit entities on a patent developed by Orkin's laboratory regarding BCL11A, a genetic switch regulating hemoglobin production that is expected to form the basis of clinical trials for gene therapy and gene editing for sickle cell disease and thalassemia.

Professor Capechi has shed light on the causes of several human birth abnormalities, while Professor Smithies has worked on the blood disease thalassemia and hypertension.

«For example, despite matching the ABO blood group antigens during red blood cell (RBC) transfusion, up to 45 percent of chronically transfused patients, such as those with sickle cell disease or thalassemia, develop antibodies to mismatched minor antigens on transfused RBCs; this process is known as alloimmunization.»

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Clinical research activities are focused on the implementation of experimental protocols based on gene or cell therapy for the treatment of genetic blood disorders such as ADA - SCID, Wiskott - Aldrich Syndrome, Metachromatic Leukodystrophy, Beta - thalassemia, Chronic granulomatous disease, Mucopolysaccharidosis Type I (Hurler).

Dr. Scriver also helped develop pediatric genetic screening programs, including one for thalassemia and another for Tay - Sachs disease, both targeted at high school students, which were shown to have lasting effects on personal and public health in Quebec.

An authority on the study and treatment of childhood cancers, as well as the biology and therapy of hemoglobinopathies — blood diseases such as sickle cell anemia and thalassemia — Cunningham is known for his work on understanding the molecular mechanism underpinning red blood cell production.

One study was done on children with Thalassemia, a genetic form of anemia, who require regular blood transfusions.

One study was done on kids with Thalassemia, a genetic type of anemia, who need frequent blood transfusions.

Exceptionally well - versed in genetics and hematology, with great focus on determining blood diseases such as Thalassemia and Leukemia.