Not exact matches
This mark (H3K4me3) modifies
chromatin — the complex of DNA and its protein
packaging — by adding three identical molecules known as methyl groups at a specific place
on a
packaging protein known as histone 3.
Cancer studies have increasingly focused
on chromatin — the intertwined proteins and DNA that are
packaged into chromosomes — because of its ability to regulate genes important for either activating or inhibiting tumorigenesis.
ATP - dependent
chromatin remodelers are enzymes specialized
on altering the structure and
packaging state of
chromatin.
Methylation is a punctuation - like modification of DNA that usually shuts genes off, and
chromatin is the term describing DNA when it is clothed by proteins such as histones, a form of
packaging that determines whether a gene is
on or off.