Then a complete tragedy occurred when I ran out of chocolate chunks
on trial numbers 3 & 4 and had to switch to chocolate chips.
Not exact matches
«We're planning to build and test ultra high - speed broadband networks in a small
number of
trial locations across the United States,» says Google
on its officail blog.
Kirra Cheers, a photographer from Brooklyn, recently set out to document her
trials and tribulations using Tinder, a wildly popular app that allows users to approve or deny potential mates based
on a small
number of pictures and a short bio.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the
number of insured patients; the possibility of unfavorable results from clinical
trials involving investigational compounds; Gilead's ability to initiate clinical
trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Affleck told defence counsel that although he understood that the sheer
number of people charged «imposed layers of complexity»
on the
trials, he was prepared to move as quickly as possible.
If you are wanting to just take it gently then why not commit so something like an xx week (pick a
number)
trial on a particular topic.
Sign up for a Sportsbook Insider PRO
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Spartak and CSKA Moscow have taken a
number of Nigerians and Ghanaians in 2016, though none were signed, while Tom Tomsk took two Libyans
on trial.
The Term Breech
Trial is the largest randomized clinical trial ever undertaken on term breech mode of delivery, and while it offered a wealth of information regarding breech birth, it also had a number of weaknesses which have been identified since its publica
Trial is the largest randomized clinical
trial ever undertaken on term breech mode of delivery, and while it offered a wealth of information regarding breech birth, it also had a number of weaknesses which have been identified since its publica
trial ever undertaken
on term breech mode of delivery, and while it offered a wealth of information regarding breech birth, it also had a
number of weaknesses which have been identified since its publication.
«We have analysed all the data and feedback and reviewed a
number of incidents including the George Smith one and we have made a few changes,» said Kemp, speaking at Twickenham
on the eve of the new Premiership season where the
trial will continue.
Cloth Diaper
trials are programs that allow you to pay a deposit
on a certain
number of diapers and try them out for a select period of time.
Finally, a Finnish
trial of universal home visiting by nurses35 and two U.S. programs implemented by master's degree - level mental health or developmental clinicians have found significant effects
on a
number of important child behavioural problems.36, 37 Additionally, a paraprofessional home visitation program found effects
on externalizing and internalizing behaviours at child age 2; however due to the large
number of effects measured in this study, replication of the findings is warranted.38
Based
on the intervention described, each
trial report is assigned a
number that corresponds to a specific Pregnancy and Childbirth Group review topic (or topics), and is then added to the Register.
Only one
trial reported the following outcomes: mean
number of antenatal visits, perceptions of control, breastfeeding
on discharge and postpartum depression and so results were not included in a meta - analysis.
A randomised control
trial conducted in BC [30] found home visits in early labour to be more effective than telephone triage in reducing the
number of women attending the hospital for assessment before they are in labour and those attending before 3 cm cervical dilation, although the home visits had no impact
on CS rates or birth outcomes.
In addition, there was no effect
on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical
trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a
number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled
trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.
Have
trialed many, many brands of all price ranges and different systems - currently with a 19 lb baby these are
number one: Soft fleecy lining wicks moisture away quickly, soft elastic legs fit comfortably with minimal marking
on baby - Pricey but we have since purchased more as they have become our «go to» for both night and day - used with single or double bamboo insert for another company.
In meta - analyses with a large
number of
trials, as is the case in this review, there is a strong possibility that a large
number of small and possibly poor quality
trials will have a substantial influence
on the result.
Based
on the intervention described, each
trial report is assigned a
number that corresponds to a specific Pregnancy and Childbirth review topic (or topics), and is then added to the Register.
«In the future, depending
on the
number of cases that will come up for
trial, the Judiciary may increase the courts and
number of Judges to ensure that the courts are not overwhelmed by the volume of work and that the cases are dealt with expeditiously,» the statement added.
Goodman was
on trial in 2013 - 14 along with Coulson, Rebekah Brooks and a
number of other former News of the World reporters and executives.
A
number of officials, including former ministers, are
on trial for allegedly compromising the 2015 elections with the sum of $ 115 million.
Thanks in part to such
trials and tribulations, the Independence Party is riding a wave of success — and not just in terms of political seats won but particularly among the rising
number of people who like to dwell
on the frontier justice of independent politics.
She said she would rule soon
on a
number of pending motions in the case, which include defense motions to dismiss the charges and to separate the
trials of the Manganos and Venditto.
That outburst has no doubt ensured the phone
number to put the only MP in the jungle up for bush tucker
trials is
on speed dial for a
number of politicians, but do not mistake criticism of her jungle trip as somehow a reaction to her own particular brand of politics.
The State Coordinator, NYSC Ekiti State, Mrs. Nwano Eze Ukgha who put the
number of youths registered in the new batch at 2,066 warned the corps members against indulging in cult activities, consumption of illicit drugs, and other forms of unwholesome acts
on the camp as erring members would be handed over to the camp court for
trial according to the by - laws.
The Government suffered a
number of defeats in the House of Lords last night
on its legislative plans for
trials held in secret.
After determining the proper dosage of tamoxifen — an early
trial resulted in a
number of mouse deaths due to overactivation of Mecp2 — researchers settled
on a four - week regimen of ramping up the gene's function.
«Industry - financed clinical
trials on the rise, as
number of NIH - funded
trials falls: Researchers concerned about trends in research funding as commercial ventures run six times more
trials than academic investigators.»
«The existing
trials also differ
on a
number of factors, such as the dose of baclofen given and the length of treatment.
The
trial enrolled 398 men with cancer that had not spread outside the prostate gland who were judged to be at high risk of treatment failure, based
on standard tests for a
number of features of the cancer.
The FDA already has a 6 - year - old program called the Critical Path Initiative that, according to its Web site, funds a
number of research projects
on topics such as clinical
trial design.
Although a
number of randomized
trials demonstrate the clear benefits of mammography screening in women up to age 74
on reducing mortality, data are sparse in women over the age of 74, especially minorities.
«Children who had low lung function at the start of the
trial followed a series of predicted growth patterns: most had reduced lung growth with time and a significant
number would go
on to meet the criteria for COPD.»
Vaccine efficacy was set at an average of 60 % (actual
numbers depended
on the different virus subtypes and
on whether a person had been exposed due to a prior natural infection) based
on recent phase III
trial results for the Sanofi - Pasteur vaccine that had shown moderate effectiveness.
«That there are a
number of clinical
trials on - going in a range of different cancers is an encouraging start.»
A systematic review of published studies
on the use of medical cannabis in children and adolescents finds a notable lack of studies and a minimal
number of the randomized, controlled
trials needed to confirm the effectiveness of a treatment.
The study was the first randomized - controlled
trial to examine the potential benefits of the low fat diet
on the management of MS.. The study found no significant differences between the two groups in brain lesions detected
on MRI brain scans or
on other measures of MS.. But while the
number of
trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies of the diet.
The next step is for grouse managers and conservationists to use the results of the model to agree
on an acceptable
number of harriers and then test the idea in a field
trial.
This
trial also looked at the effects of corticosteroids
on HIV - positive people, but the small
number of included participants meant that the review authors were unsure if the benefits in terms of a reduction of death was preserved in this group of participants.
Only a couple of these synthetic DNA drugs are
on the market, but a
number are in clinical
trials, including a potential treatment for ALS, also known as Lou Gehrig's disease.
By combining two or more of these outcomes to create a single category, you can say it helped «A and B» even if it only helped A and not B. For example, although there was no statistically significant effect from tPA in the NINDS
trial on the
number of patients who died, there was a small decrease in disability for those who survived.
The
number of total simulator collisions, off - road collisions,
on - road collisions, center - line crosses and off - road excursions were recorded at each
trial.
This likely contributed to the lower - than - expected
number of deaths
on both arms in the
trial.
«Lithium, long used in mental health as a highly effective mood stabiliser, has been
on the radar as a potential disease modifying treatment for Alzheimer's disease with positive evidence from preclinical studies and a
number of small clinical
trials.
The different arms of the
trial were very well - matched as regards age (average age ≈ 55 y, ± 5 - 7 y depending
on subgroup), education, time from onset of disease, and MDS - UPDRS scores at onset; the only evident differences were a higher
number of males and higher body weight in the low - dose treatment group.
Based
on positive results produced from a
number of scientific clinical
trials, coronary artery disease therapy using adult stem cells is a promising new method of treatment for coronary artery disease patients.
That's a small
number, but if the drug is safe they'll move
on to bigger
trials with more people to look at whether it's actually working.
Correction: The
number to call for more information
on the diabetes clinical
trial is 858-657-7039.
«We have a larger
number of patients in our group than
on any single clinical
trial, so we hope this will be an opportunity for researchers to learn about us and a way for us to learn more about our condition.