Sentences with phrase «on tumor formation»

Not exact matches

For example, genes involved in suppressing tumor formation are turned off via epigenetic mechanisms, and genes involved in rapid growth and replication are turned on too high.

Niswander hopes her findings will provide insight into tumor formation, where cells don't die on cue.

Although the researchers were predominantly interested in broccoli's impact on the formation and progression of cancerous tumors in the liver, Jeffery explained that they also wanted to observe the health of the liver and how the liver was metabolizing lipids because of the high - fat diet.

«Treatment as it stands now is not based on the molecular abnormalities that drive brain tumor formation,» Miller said.

«These strategies would focus on promoting myelination in the peripheral nervous system for neuropathic disease or inhibiting Schwann cell over-proliferation that occurs during formation of peripheral nerve sheath tumors like neurofibromas.»

«For example, in certain cancers, genes may be switched on at the wrong times, eventually leading to the formation of tumors,» said Brandon Razooky, a Gladstone and UCSF graduate student and the paper's other lead author.

To explore the biological function of DDX3 on cell growth control, a colony formation assay was done in several tumor cell lines (HuH - 7, HCT116, and HeLa) and normal murine fibroblast cells (NIH 3T3) under the selection of G418.

She is institutional principal investigator of the Phase I Consortium Study in New Agents in Neuroblastoma Treatment and directs NIH - funded work on effects of SPARC (secreted protein acidic and rich in cysteine, an amino acid) on neuroblastoma tumor growth and blood vessel formation.

Despite a large amount of work that has concentrated on understanding colon tumor formation, we still do not know the full complement of molecular lesions that are individually necessary (and together sufficient) to cause colorectal cancer.

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.

Silencing of the enzyme stimulated vessel formation, but paradoxically resulted in a profound reduction of tumor growth; an effect that relies on the anti-proliferative nature of the TGFβ signaling pathway, in a largely HIF1α - independent manner (Klotzsche - von Ameln et al., Cancer Res., 2011 and Cancer Biol Ther., 2012).

Colon cancer occurs when high levels of dietary vegetable oils and hydrogenated fats, along with certain carcinogens, are acted on by certain enzymes in the cells lining the colon, leading to tumor formation.14 This explains the fact that in industrialized countries, where there are many carcinogens in the diet and where consumption of vegetable oils and carcinogens is high, some studies have correlated meat - eating with colon cancer; but in traditional societies, where vegetable oils are absent and the food is free of additives, meat - eating is not associated with cancer.

On the other hand, estrogen out of balance with other essential hormones, including progesterone and testosterone, becomes destructive, encouraging and feeding the formation of tumors and cancer.

Polyunsaturated fats such as corn oil and soybean oil are highly unstable and vulnerable to oxidation — and oxidation, in turn, is linked to cancer — while the omega - 6 fatty acids that predominate in vegetable oils have been shown to accelerate the growth of tumor cells.6 As Fallon and Enig explain, 4 excessive consumption of toxic polyunsaturated oils — not red meat — represents a known mechanism for colon cancer: «Colon cancer occurs when high levels of dietary vegetable oils and hydrogenated fats, along with certain carcinogens, are acted on by certain enzymes in the cells lining the colon, leading to tumor formation» [Emphasis added].

Standard chemo with radiation actually intentionally induces formation of free radicals which has a selective effect on tumors and normal tissue.

Despite the extremely low incidence of this problem, the problem is still very serious and the veterinary profession has responded with numerous studies on how vaccines might be related to tumor formation, why is the incidence so low given how many vaccines are given to cats annually, what can be done for prevention.

Malignant tumors are more likely to be rapidly growing, have ill - defined margins, infiltrative, and may be ulcerated (a formation of a break on the skin).

Despite the extremely low incidence of this problem, the problem is still serious and the veterinary profession has responded with numerous studies on how vaccines might be related to tumor formation, why the incidence is so low given how many vaccines are given to cats annually, and what can be done for prevention.