Sentences with phrase «on tumor type»

Depending on the tumor type and location, your veterinarian may recommend adding other treatments such as chemotherapy or radiation therapy.

The biological behavior, prognosis, and treatment of these tumors depends on tumor type, primary site (location), and extent of disease (stage).

The growth rates of pituitary tumors in dogs and cats vary greatly, and the rate at which symptoms progress depends on tumor type.

Depending on the tumor type and location, your veterinarian may recommend adding other treatments such as chemotherapy.

IGRT use also varied across consortium facilities depending on tumor type.

In blood samples from 1005 patients with eight types of tumors that had evidently not yet metastasized, the test detected between 33 % and 98 % of cases, depending on the tumor type (see graph, above).

Not exact matches

So research teams began souping up various types of immune cells and even targeting them to specific protein markers on tumors.

We're also making progress on our liquid biopsy program since our last update, including the recently announced collaboration with Memorial Sloan Kettering Cancer Center, which is focused on furthering the basic understanding of the biology of circulating tumor DNA, or ctDNA, in different cancer types.

Drug developer Loxo Oncology said on Tuesday it is partnering with genetic testing company Illumina Inc on a diagnostic tool that will work with Loxo's larotrectinib and another one of its experimental cancer drugs, across tumor types.

April 10 Drug developer Loxo Oncology said on Tuesday it is partnering with genetic testing company Illumina Inc on a diagnostic tool that will work with Loxo's larotrectinib and another one of its experimental cancer drugs, across tumor types.

Topical application of capsaicin on the dorsal skin of 7,12 - dimetylbenz (a) anthracene — initiated and TPA - promoted TRPV1 wild - type (WT) and TRPV1 knockout (KO) mice induced more and larger skin tumors in TRPV1 / KO mice, suggesting a TRPV1 - independent mechanism.

They found that this substance had some effect on up to 40 different tumor types.

For example, TCGA, with genomic data on 33 tumor types taken from samples from 11,000 patients, is finishing 2018 by publishing a series of papers and holding a symposium.

They found that depending on the cell of origin, mutations in PIK3CA and p53 induced very different types of tumors.

«We now hope to move on to investigate how these bacteria contribute to the development of the characteristic stomach tumor types that are associated with each of these conditions.»

This bumped up sensitivity and allowed the team to home in on the tissue type of the tumor.

Differences in these processes and their effects on the stomach could help explain why H. pylori is more commonly associated with a cancer type known as gastric adenocarcinoma, while autoimmune disease is linked with neuroendocrine tumors.

One advantage of this method is that it only activates a certain type of immune cell, the dendritic cell or T - cell, and only in one part of the body, near the draining lymph nodes or tumor, which helps cut down on the system - wide side effects often seen with chemotherapy.

Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.

When breast cancer is diagnosed, the drug regimen that the patient receives is based primarily on the results of a biopsy that is used to identify the type of tumor she has.

Caris performed the molecular profiling on 48,733 solid tumor samples to assess the prevalence of homologous recombination deficiency in about 20 different types of solid tumors.

«We've had luck with other types of cancer in removing the brakes on the immune system to allow it to fight the tumors, but this has not been the case with glioblastoma,» said study author Anhua Wu, MD, PhD, of the First Hospital of China Medical University in Shenyang, China.

New technologies are coming to the fore that allow interrogation of the types of cells interacting with tumors, in particular providing intelligence on the broad variety of complex associations between tumor cells and the immune system.

Cohabitation erased the difference in tumor growth, indicating it depends on the types of microbes in the rodents» guts.

Though vestibular schwannomas affecting both sides are the hallmark of neurofibromatosis type 2 (NF2), a genetic disorder causing tumors to grow at multiple sites throughout a person's life, vestibular schwannomas may also occur sporadically, and on one side only.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

In the United States, the ABI is approved for use only in patients 12 years or older with neurofibromatosis type II, an inherited disease that causes a non-malignant brain tumor on the hearing nerve, but it has shown limited effectiveness in adults.

Successful treatment depends in part on accurately identifying the type of tumor, but this can be difficult.

Across all four cancer types, the new method of selecting candidate genes based on inter-tumor variation in gene expression outperformed the other methods, including the standard method of comparing mean expression in adjacent normal and tumor tissues.

«It was hard to find a single microRNA in the human genome that wasn't differentially turned on or off across different tumor types in different tissues,» Golub says.

Dr. Le, who holds the Thomas L. Shields, M.D. Professorship in Dermatology, said he and his researchers serendipitously uncovered this explanation for balding and hair graying while studying a disorder called Neurofibromatosis Type 1, a rare genetic disease that causes tumors to grow on nerves.

In a report on one of the two findings, published online Sept. 20 in Acta Neuropathologica, the investigators identified alterations in a protein known as ATRX in human brain tumors that arise as part of a genetically inherited condition known as neurofibromatosis type 1 (NF1).

There are different types of glioma, classified according to an established system based on which cell type the tumor arises from.

Depending on the type of tissue, it plays different protective and mechanical roles, but it has also been shown to be involved in a number of diseases, including the growth of cancer tumors.

IL - 6 is a cytokine, a signal molecule that is produced and secreted both by immune cells and by tumor cells and binds specifically to a receptor (IL - 6R) that is found on the surfaces of many cell types.

Occurrence of this type of tumor on the tongue is exceedingly rare, says author Dr Manisha Biradar.

Another possibility that Irvine's lab is working on is developing treatments that could be used against tumors even when scientists don't know of a specific vaccine target for that type of tumor.

The screening revealed coibamide A to be capable of killing many types of cancer cells, but Ishmael decided to focus subsequent studies on two types in particular — brain tumors, or glioblastomas, and a breast cancer subtype known as triple negative breast cancer.

Since SFRP2 is expressed in many cancers — including breast, colon, pancreas, ovarian and kidney tumors — the technique could potentially be useful on a broad range of cancer types.

They found that carcinoma cells from smokers carried the «transcriptional fingerprint» (i.e. the pattern of genes that were switched on or off) of basal cells, suggesting that the tumors may originate from this type of cell.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

The circuit, which can be customized to respond to different types of tumor, is based on the simple AND gates used in electronics.

This week, researchers at the National Cancer Institute (NCI) unveiled a project on their wish list: a much broader survey of 10,000 tumors per cancer type that would aim to pin down very rare cancer genes.

Antibody that blocks a «do not eat» flag on cancer cells turns the immune system against all tumor types

«Conversely, the necrotic part of the tumor is driven by a distinct set of glioma stem cells utilizing the BIM1 pathway and are characterized by a mesenchymal, inflammatory cell type dependent on glucose metabolism in the absence of oxygen.

Tumor cells metastasized to bone modify the activity of these cells and, depending on the type of cancer, cause osteoblastic or osteolytic changes.

By analyzing a dataset of human immune cells stimulated with interferon — a signaling protein created in response to pathogens or tumor cells — the team could precisely identify which genes were switched on in each of 13 responding cell types.

«We have developed computer - based algorithms that reliably differentiate 82 types of CNS tumors based on their methylation patterns,» said Professor David Capper, who is one of the four first authors of the study.

Baltimore, Md. (Embargoed until 12:30 pm EDT on Monday, June 8)-- A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

While the study focused on the T - cells around a lymphoma tumor, this research is pertinent to all types of cancer.