Sentences with phrase «on tumor viruses»

His research in the 1970s had focused on tumor viruses because they were thought to alter human genes, thereby causing cancer.

Around 1984, when a student of his pointed out that Duesberg had not attended a West Coast meeting of scientists working on tumor viruses, he suddenly realized that he was no longer being invited to the informal meetings.

Not exact matches

A new generation of oncolytic viruses are entering late - stage clinical trials, repurposing smallpox and herpesvirus to take on tough tumors

The issue now is not whether viruses cause human tumors (as perhaps they may, on occasion) but rather how much can be learned from tumor virology about the mechanisms by which human tumors arise.

The immune system depends on molecules called T cell receptors on the surface of T cells to recognize and respond to foreign antigens from virus - infected cells, tumors and other threats.

For some cancer patients, viruses engineered to zero in on tumor cells work like a wonder drug.

To bring the wrath of the immune system down on tumors, researchers have tried shooting them up with a variety of molecules and viruses.

Don Diamond, a virologist at the City of Hope Cancer Center near Los Angeles, agrees: his extensive research on CMV and cancer has convinced him the virus does not cause tumors.

For the CRISPR trial, a UPenn - led team wants to remove T cells from patients and use a harmless virus to give the cells a receptor for NY - ESO - 1, a protein that is often present on certain tumors but not on most healthy cells.

These cells are on high alert for pathogens such as viruses, bacteria and even tumor cells, signaling the body's T - cell immune fighters into action when sensing harmful invaders.

The result — still a preliminary finding — illustrates the potential for improved cancer treatment through saddling a cancer - killing virus on the back of a tumor - targeting immune cell.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

After two years of post-graduate studies at the Max Planck Institute for Biochemistry in Munich, Dr. Jaenisch set his sights on a postdoctoral position in the United States, and joined Arnold Levine at Princeton University to work with tumor viruses in mammalian systems.

If the virus is igniting a fire within the tumor, we want to see if we can use these immune modulators to pour gas on the flames.»

From there they showed that cancer cells had lost structural polarity, resulting in random distribution of CAR receptors on their surface, thereby allowing the virus to attach to and infect the tumor cells.

Other scalable systems include cell lines based on the Henrietta Lacks tumor (HeLa) and baby hamster kidney (BHK - 21) cells for adenovirus serotype 5 (Ad5) and herpes simplex virus 1 (HSV - 1) production (4, 40, 41).

Hunter's breakthrough, which set the story in motion, was a product of basic research on a chicken RNA tumor virus: the 1979 discovery of the first tyrosine kinase paved the way for our understanding of how cells perceive their environment and respond appropriately to growth signals.

«It will critically inform the medical community on whether this combination approach, using an oncolytic virus followed by a checkpoint inhibitor, will be the next step in the successful treatment of brain tumors in both people and pets.»