Sentences with phrase «on uncertain market»

Not exact matches

However, the bigger concern is that this is one more threat to your retirement nest egg, on top of low interest rates, a low - growth economic outlook, uncertain stock markets and potential government cuts to other programs, such as health care and nursing - home subsidies.

«The full effect of Brexit is uncertain and depends on any agreements the United Kingdom may make to retain access to European Union markets,» the filing reads.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

«When markets are uncertain, you err on the side of caution.

Futurpreneur Canada works with aspiring and established young entrepreneurs, with many citing a desire to rely on their own skills and persistence rather than an uncertain job market.

Although shareholders have yet to approve the deal, the banks would «re-pay shares at a pre-defined value in next few months, avoiding the risk of uncertain evolution of huge claims by shareholders and clients,» Maria Paola Toschi, global market strategist at JPMorgan Asset Management, told CNBC on Tuesday via email.

We also know that, in uncertain markets, it is still better to stay the course, grab on to the side of the kayak and ride through the whitewater of the markets» concern de jour.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

It's uncertain how effective the new addition will be in taking on Amazon, which already seems to have established itself as a leader in the online market.

As the advertising market remains uncertain, the Times is relying more on its readers to support its journalism.

Career marketer Kathy Baughman shares tips with future CX leaders on how to forge a successful marketing career path, no matter how winding or uncertain.

Given some evidence — uncertain and shaky to be sure — that the job market has cooled a bit while inflation is non-threatening, from what I see from here, the Fed should revert to data - driven mode and punt on a June hike.

Read on to find out how I handle an uncertain market.

Following the announcement of new US sanctions on Russia, the Russian equity market and the ruble have been volatile, and the environment remains fluid and uncertain.

Two weeks into his term and the president has been focused primarily on immigration and trade, causing a reevaluation among analysts at some banks that harks back to pre-election concerns about Trump's uncertain effect on markets and U.S. economic growth.

It should reduce demand, «but the impact of these policy measures on the market is uncertain,» it said.

The problem is that this process is unprecedented, will take considerable time to complete and it outcome is necessarily uncertain — points of risk were spelled out pretty clearly in the latest bidder statement Murray Goulburn offered the market on Monday.

Today's students are, as he says: «highly anxious about taking on an average of # 44,000 worth of debt in an uncertain job market where nearly half of employed recent graduates are in non-graduate jobs.»

Shame on the Congressional Clown pols that are fiddling for personal gain and posturing as the nation and the financial markets wobbled through another week, uncertain that in the end the folks that represent the people will get it at least partially right.

Construction unions and developers were unable to come to an accord on prevailing wage standards to be written into the 421a tax exemption by today's deadline — meaning the abatement will die on the vine, and the future of the New York real estate market will be left uncertain.

Mr Miliband took an uncertain line on the capacity of the market to reduce emissions.

«People are comfortable with the idea that stock markets, housing prices and the weather are uncertain, and they are used to making decisions on that basis,» he notes.

In a fashion market being reshaped by digital media, rapid globalisation and an uncertain economic and geo - political environment, more and more brands are rethinking their approach to where, when and how to present their collections, putting pressure on traditional fashion weeks to evolve.

This is an inherently uncertain exercise, which depends among other things on predicted future stock market returns.

Australia has been an important market to Kobo since the launch of their e-Reader last year, but their future on the other side of the pond remain uncertain due to their entire... [Read more...]

Australia has been an important market to Kobo since the launch of their e-Reader last year, but their future on the other side of the pond remain uncertain due to their entire distribution chain wallowing in bankruptcy.

The all - star speakers will share invaluable insights on how to navigate today's uncertain markets....

If you want to zero in on the fast - rising stocks in today's uncertain market, you'll want to take advantage of my proven investing approach.

The dividend reflects certainty, the stock price growth is uncertain, dependent on the market moods.

IG also became one of the numerous forex brokers to temporarily hike the margin requirements on some of its instruments, in order to minimize the risk from the extreme market volatility surrounding the referendum and its uncertain outcome.

When the markets are bullish, focus on the 60 % and 80 % equity allocation ETFs and when bearish or uncertain switch to the more conservative 40 % equity allocation.»

However, it's worth highlighting fresh anxieties over Chinese / emerging market growth mean the timing of this convergence has become that much more uncertain... On the other hand, CRH is still the Irish blue chip for domestic & international investors (well, even though it's not very Irish...)-- so I'll continue to assign a 0.7 P / S multiple.

This is what David Dreman called investor overaction, when the economy is growing investors bid up equity prices too high, and when the economy is sour and the future is uncertain the market overreacts on the down side.

Just hours before the 2016 edition of the Art Dealers Association of America's fair The Art Show opened to VVIPs on Tuesday, ADAA's recently appointed president Adam Sheffer answered the question he may not have wanted to tackle: How will the uncertain art market affect this year's fair?

The findings postponed a December auction in Paris, but effects on the market remain uncertain at this point.

But the economics remain uncertain, he warned, For now, he said, the biggest impediment may be that the market price of offshore wind energy is about 50 percent higher than that of energy generated on land.

Consistency in business means security, the ability to ride through the peaks and valleys of an otherwise uncertain legal market and to focus on getting results for your clients.

The number of newly qualified (NQ) lawyers accepting roles at the UK's top 20 law firms has fallen 6 % year - on - year as the effects of the uncertain market continue to be felt at the lower end of the profession.

The ROI on law school is simply not great given the «risk» of a much more uncertain market with diminishing roles for those in the early stages of their career.

We see this on a growing number of job descriptions, as firms recognise that uncertain markets only increase the need to adapt and innovate.

It remains uncertain whether or not Bisto will ever see the light of day, and if it does, we're not sure if Google plans on marketing it to mainstream customers.

Therefore, while the effect that the Metropolis fork will have on the market is uncertain, this upgrade will prepare the Ethereum network for a long, fruitful, and busy life.

I hope that the Hays Global Skills Index 2017 provides not only a useful insight into the worldwide labour market, but some food for thought on how business can navigate uncertain times and ensure people and talent are at the heart of business strategies for growth and success in the years to come.

Usually, the path for a new business venture is rather uncertain and a lot depends on timing and market readiness.

Depending on her age and parenting status, she looks to an uncertain future which requires her to enter the job market and perhaps develop a career in order to enhance her future earning capabilities.

Their impact on real estate markets may be uncertain, but Leading Real Estate Companies of the World ® (LeadingRE) Chief Economist Marci Rossell remains optimistic about the economic effects of these events.

In this increasingly uncertain market environment, banks are looking to close the loans that make the most business sense, on properties that will hold their value over time.

The compounding wealth impact of that forced appreciation, cash flow, perpetual principle pay down (and long - term market appreciation, to a lesser extent) allow some investors to not have to worry or focus heavily on all the... flations mentioned (it provides more freedom from those concerns or uncertain market forces).