Sentences with phrase «on whole genome sequencing»

The University of Missouri will soon be working on whole genome sequencing for some breeds affected by epilepsy.

The initiative aims to propel new initiatives in the life science sector with a focus on whole genome sequencing and biodiversity.

Other contenders have until May 2013 to sign up, but «a lot of companies are not focusing on whole genome sequencing,» says Campany.

Therefore, Danny Miller, an MD - PhD student at the University of Kansas Medical Center who is conducting his doctoral research in the Hawley lab, had to rely on whole genome sequencing and new computer algorithms to pinpoint the locations of both kinds of events.

Not exact matches

With all due respect, if you'd read the actual study, you would see that this was not a whole genome sequence comparison; rather it was a comparison of mitochondrial 12S rDNA and 16S rDNA sequences for the purposes of confirming the species relationship between the Pod Mrcaru lizards (P. sicula), the source population from Pod Kopiste (also P. sicula), and the original indigenous population on Pod Mrcaru (P. mellisellensis).

In 2014, biologists published an avian tree based on the sequences of whole genomes of about 40 species.

Gire et al. describe Ebola epidemiology on the basis of 99 whole - genome sequences, including samples from 78 affected individuals.

However, Manogue said it's not clear that whole - genome sequencing infringes on the rights of gene patent holders.

«Depending on the research questions, it may also be important to define the appropriate strategy to use, either whole - genome sequencing or just targeting some genomic regions with a gene baiting approach,» says Besnard.

The research is based on whole exome sequencing (WES), which is the part of the genome translated into proteins.

The research groups then examined the landscape of the pancreatic cancer epigenome using a combination of stains on patient tissues, direct examination of the proteins that wrap DNA and whole - genome sequencing of the detected epigenetic changes to map precisely where they were located.

Therefore, whole genome sequencing was performed on a total of 76 patient isolates, including up to two repeat isolates from patients who tested positive for MRSA in the first screen.

«A striking feature of the phylogenetic tree based on S. aureus whole genome sequencing was the presence of multiple distinct clades,» said senior author Sharon Peacock from the University of Cambridge and Wellcome Trust Sanger Institute.

In the September issue of G3, Cuomo et al. unveil the first whole - genome sequence of a clinical sample of C. krusei, providing leads on genes that may be important for the species» fluconazole resistance.

We're now doing whole genome sequencing on these samples.»

After the sorting, we performed whole genome amplification on individual aggregates then sequenced the 16S rRNA marker genes to identify cells comprising the aggregate.

Sequencing the whole genome of a fetus could provide a medical early warning on a previously unknown scale - but it also brings dilemmas, says Harriet A. Washington

The researchers were able to develop a simple approach for reliable real - time tracking and prediction of viral evolution based on whole - genome sequences of influenza viruses.

The human genome contains about 3 billion base pairs, but only about 2 percent of these base pairs represent protein - coding genes, meaning that whole - exome sequencing measures the genetic alterations focused on a small but very important fraction of the genome (as opposed to techniques of whole genome sequencing, which measures every nucleotide across the entire genome, regardless of whether these genes are expressed or silent).

Together with the French gene sequencing center Genoscope, in the Paris suburb of Evry, Celera will perform the initial sequencing using the «whole - genome shotgun» approach it unleashed on the human genome.

We have applied «whole - genome shotgun sequencing» to microbial populations collected en masse on tangential flow and impact filters from seawater samples collected from the Sargasso Sea near Bermuda.

The Yale - led study performed whole exome sequencing ¬ — a technique for sequencing all the expressed genes in a genome ¬ — on TNBC tumors to identify mutations in specific genes or pathways that may indicate response or resistance to the standard of care, which is anthracycline / taxane (ACT) chemotherapy.

These clumps of genes are flanked on each end by DNA sequences known as mobility units, which make them prone to moving between genomes as a whole.

They developed a pipeline that combined fosmid - pooling strategy with whole - genome shotgun strategies, based solely on next generation sequencing (NGS) and hierarchical assembly methods.

Western Pygmies I love population genetics for its ability to peer back into human history through the medium of DNA's ATCGs.One of the stars of this discipline is Sarah Tishkoff, a standout in African genetics, someone who will readily haul a centrifuge into the bush in Cameroon.Tishkoff of the University of Pennsylvania is lead author on a paper published online July 26 in Cell that details whole - genome sequencing of five individuals each from three extant hunter - gatherer groups — the Pygmies of Cameroon as well as the Hadza and the Sandawe of Tanzania.

NJ trees were constructed for the whole - genome SNP set using the ape R package46 using distance matrices based on the metric of sequence divergence from Gronau et al. 25.

With the availability of genome sequences from representative species in whole phyla, rigorous quantitative measurements of genetic distance based on DNA sequence divergence has been used to test existing evolutionary trees and to re-classify organisms in all kingdoms.

As the justices prepare to hear arguments in the Myriad Genetics case, observers are debating the impact of the outcome on personalized medicine and whole - genome sequencing

«Because this was the first outbreak of CRKP in the Chicago region, we decided to try to trace its initial movements based on patient transfers and whole - genome sequencing of samples.

After decades of extrapolating about gene function in trees based on gene function in a tiny, less complex plant, a team of scientists has sequenced whole genomes — determined the DNA sequence of all the genes — from 544 unrelated trees of the same species.

I will review recent advances in the use of nanopore sequencing for clinical microbiology and human genetics, including our collaborations on viral and bacterial diagnostic sequencing, real - time surveillance, direct RNA and human whole - genome sequencing, and discuss the opportunities and barriers around moving to sequencing as a routine test in the clinic.

Today we'll delve into another paper in the same issue on the attitudes of genetics professionals on return of incidental findings from whole genome sequencing (WGS) and exome sequencing (ES).

Zhang et al performed whole - genome sequencing on tumor samples and matched normals from 12 children with ETP - ALL.

We expanded on our genome sequencing efforts to include efforts in whole genome gene expression analysis and functional analysis of genome variation.

They sequenced two clones each from 24 populations after 2,000 generations and performed whole - genome whole - population time - course sequencing on two populations.

Whole genome sequencing has been completed on both Kelly brothers and has shown hundreds of unique mutations in their genome, which is normal.

The work consisted of performing whole - genome sequencing on 1,011 samples of yeast which yielded 1,625,809 high - quality reference - based SNPs.

Next generation sequencing was to include whole exome sequencing (WES) and whole genome sequencing (WGS) and analysis on large numbers of well characterized subjects to identify AD risk and protective gene variants.

The Family - Based study includes whole genome sequencing (WGS) on multiplex families where DNA for at least two members per family was available and includes Caucasians and Caribbean Hispanic families.

Next generation sequencing includes whole exome sequencing (WES) and whole genome sequencing (WGS) and analysis on large numbers of well characterized subjects to identify AD risk and protective gene variants

«Analysis of the bread wheat genome using whole genome shotgun sequencing» is published online in Nature on November 29, 2012.

As is often the case for yeast, the ability to sequence and analyze whole genomes at very deep coverage has yielded broad insights on eukaryotic genome evolution.

After the completion of the S. cerevisiae genome he continued to sequence whole genomes of other microbes and also worked on novel anti-cancer agents.

In the very near future, it may become feasible and cost - effective to perform whole - genome sequencing (WGS) on hundreds or thousands of tumors of a certain type to exhaustively identify recurrently mutated genes.

Ongoing T2D research activities at CRGGH include 1) whole - exome sequencing of African families with at least four affected members (data generation is complete and analysis is ongoing), 2) GWAS of 1,200 cases and 1,200 controls from West Africa using the new and more efficient African - centric Affymetrix Axiom genome - wide array with more than 2 million markers, and 3) whole genome expression analysis on skeletal muscle obtained from biopsy from 45 subjects (expression QTL (eQTL) studies on the dataset are complete).

Chowdhury tells The Scientist that his group at Rady Children's, which has performed rWGS on about 150 infants, is «in talks with multiple children's hospitals» around the U.S. in the hopes that many more children in NICUs will have their whole genomes sequenced in the near future.

Sequencing the whole genome of a fetus could provide a medical early warning on a previously unknown scale - but...

SciLifeLab has now announced giving 33 million SEK to 14 sequencing projects focused on human whole genome sequencing and biodiversity under the SciLifeLab National Sequencing Projects isequencing projects focused on human whole genome sequencing and biodiversity under the SciLifeLab National Sequencing Projects isequencing and biodiversity under the SciLifeLab National Sequencing Projects iSequencing Projects initiative.

PHG Foundation has previously carried out work examining the implications of whole exome and genome sequencing on clinical services which identified data sharing as a key priority for these technologies to be deployed effectively for clinical benefit.

I am also involved in making various types of amplicon as well as whole - genome shot gun libraries to sequence on different illumina platforms (MiSeq, NextSeq, HiSeq) and PacBio to study the relationship between microbiome and several diseases.