Not exact matches
«Using
yeast as a
model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned
on remain inactive.»
«One of the things that appealed to me [about Fink's lab] was working
on more than one
model organism, applying insights from
yeast genetics to Arabidopsis,» Niyogi recalls.
Given his training in developmental biology, Raman focused the team to seek a novel drug target
on genes important to the development of
model organisms — fruit flies (Drosophila) and
yeast (Saccharomyces cerevisiae)-- rather than
on oncogenes that transform a normal cell into a cancer cell.
Chung and Khurana used the wealth of data from the
yeast alpha - synuclein toxicity
model to clue them in
on key cellular processes that became perturbed as patient neurons aged in the dish.
In addition, projects to perform genetic interaction screens
on disease genes in
model organisms (
yeast, worm, fly, fish) will not be considered, unless the project includes substantive specific aims that investigate the disease relevance of any new genes discovered in human or mammalian
model systems.
The researchers focused
on a well - known enzyme — called RNA polymerase II (RNAPII)-- and used the single - cellular
yeast species S. cerevisiae as a
model.
«I have been working
on yeast genetics as a
model to study cancer.
Geneticists across the
model organism and human genetics communities recognize Hieter for his dedication to uniting human biologists with those who work
on model organisms such as mice, fruit flies, worms, and
yeast.