Sentences with phrase «on zebrafish»

Further research on this zebrafish FA model will lead to a deeper understanding of the molecular basis of bone marrow failure in FA and the cellular role of RAD51.

Some customers have successfully used ab7260 on Zebrafish lysates; however we have conflicting data to suggest that not all batches will be suitable for work on Zebrafish.

Although you can see the effect of the mutation on the zebrafish embryo, you do not know which gene is affected.

Differential effects of thin and thick filament disruption on zebrafish smooth muscle regulatory proteins.

Finally, in [16], the robotic fish is utilized as a tool to analyze the effect of ethanol administration on zebrafish behavior.

Future work will be driven in several directions, including the dependence of zebrafish shoal size on its response [56] to the robotic fish, and conversely, the dependence of the size and configuration of a shoal of robotic fish on zebrafish response.

In the team's studies on zebrafish embryos, the embryos responded to a magnetic field by twirling, which they generally do in response to pressures in the water.

«Using calcium imaging on zebrafish, we were able to visualize an on - going process of memory consolidation for the first time.

Vitargent has also developed a dioxin test on zebrafish (Danio rerio).

McDermott's team discovered hair cells on the zebrafish skin use different mechanotransduction genes — like tmc2b — depending on their orientation.

New research from a team including Carnegie's Daniel Gorelick and Marnie Halpern on the effects of these chemicals on zebrafish shows that embryonic heart valves could be particularly in danger.

In tests on zebrafish, flies and mice, scientists found that treating the disease with purified quercetin — which targets beta - catenin — led to a significant improvement in the health of nerve and muscle cells.

As a next step, Dr. Reimer's research team intend to analyse the effect of different drugs on zebrafish OPCs in order to potentially identify a method to improve functional spinal cord repair in humans.

The protein itself has been known to researchers for some time as a result of research on zebrafish, where it plays an important role in the healing process following damage to the spinal cord.

The centre will be structured around six technical platforms focusing on zebrafish transgenesis and micromanipulation, bioimaging, mouse transgenesis, flow cytometry, stem cell culture, and gene - expression analysis.

In experiments on zebrafish, Freiburg researchers have demonstrated that the same proteins that lead to the formation of metastases in humans also cause the cells to migrate during embryonic development.

Testing the titanium sub-oxides on zebrafish (the aquatic cousin of lab rats) showed it to be toxic when ingested; the toxicity was significant in tissue not exposed to sunlight.

Not exact matches

To automate that process, the zebrafish were oriented either laterally or dorsally once they arrived on the viewing platform.

The scientists hope their findings on cell migration in zebrafish will open up new perspectives for research on proteins that control metastasis and thus the malignancy of cancer.

Furgeson and his colleagues said that zebrafish could be used to identify «nanomaterial characteristics that afford minimal or no toxicity and guide more rational designs of materials on the nanoscale.»

«Zebrafish study sheds new light on human heart defects.»

Then, on the morning of the 16th, something strange was reported about the zebrafish.

Building on the evidence that microglia were in play during injury, the researchers conducted tests in zebrafish with the specialized enzyme incorporated into both rod cells and microglial cells, removing both cell types to ask what role microglia play during regeneration.

When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.

Based on analyses of scales from highly relevant species for aquaculture such as common carp (Cyprinus carpio), gilthead sea bream (Sparus aurata), sea bass (Dicentrarchus labrax), Mozambique tilapia (Oreochromis mossambicus), Atlantic salmon (Salmo salar), rainbow trout (Oncorhynchus mykiss) and pike perch (Stizostedion lucioperca) as well as from fish commonly used in experimental studies such as zebrafish (Danio rerio), it was found that glucocorticoids, especially cortisol, incorporate in fish scales over time.

The group also plans to follow up on other proteins secreted after injury that were identified in their initial search, which may provide additional hints into the zebrafish's secrets of regeneration.

When zebrafish with the green fluorescing endothelial gene matured, the researchers observed green FGPs on the surface of the fish's brains — confirming that these cells arose from endothelial tissue.

In the current study, the researchers showed that FGPs are present on the surface of the zebrafish brain and that these blood vessel - associated FGPs do not arise from the immune system, as had been previously thought, but from endothelial cells themselves.

We have been using cell culture models and zebrafish as an assay to determine the effects of BMP on signaling, but we also want to be able to understand what the effect of the mutation is in the tissue and organ systems.

These studies demonstrate that inflammatory intestinal pathologies, such as Hirschsprung - associated enterocolitis or inflammatory bowel disease, can be explained as an overgrowth of certain pro-inflammatory groups of bacteria or a loss of anti-inflammatory bacteria, said Judith Eisen, a professor of biology and an expert on gut neurons in zebrafish.

Building on traditional SIM technology, the iSIM allows real - time, 3 - D super resolution imaging of small, rapidly moving structures — such as individual blood cells moving through a live zebrafish embryo.

Gorelick, the lead author, Halpern and Alice Hung of Carnegie, along with Luke Iwanowicz and Vicki Blazer of the Fish Health Branch of the U.S. Geological Survey, used genetically modified zebrafish that show estrogen receptor activity on a cell's DNA.

Luckenbach: «Many effects of substance mixtures may be explained on the basis of the zebrafish Abcb4 protein activity.

«Based on this data we concluded that the zebrafish Abcb4 protects the embryo against the toxic impact of chemicals by keeping them out,» says Luckenbach.

Boyden's team has also worked on the brains of fruit flies and zebrafish, while a collaborating group is applying expansion microscopy to human brains.

Spiked structures on male zebrafish pectoral fins are important for mating but also produce a potent signaling inhibitor.

In raising the first germ - free zebrafish, the team has produced «extremely powerful tools for examining the influence of beneficial bacteria on animal development,» says microbiologist Margaret McFall - Hgai of Kewalo Marine Laboratory in Honolulu, Hawaii.

«We discovered that male zebrafish have a very important set of structures on their pectoral fins that they use for breeding and that these structures secrete a potent molecular inhibitor of a key signaling pathway to aid their cycles of regular replacement,» explains senior author Kenneth Poss of Duke University Medical Center.

Genetic modification in zebrafish models is cheap and easy, so authors point out that future research on these animal models will contribute to understand the molecular relationship that exists between the proteins involved in the physiopathology of megalencephalic leukoencephalopathy.

CAMBRIDGE, MASSACHUSETTS — It took more than a year of fussing with tape measures, typing out a 13 - centimeter stack of pleading memos, and haggling with her department chair, dean, and provost, but Nancy Hopkins finally won an additional 19 square meters of lab space to expand her promising work on the mutagenesis of zebrafish.

Recent studies on species such as zebrafish showed scales and teeth developing from distinctly different clusters of cells in fish embryos, pouring cold water on «teeth from scales» theories.

Most notably, the studies are based on transient transfection of wild - type and mutant gene constructs into cultured cells or into zebrafish embryos and are unlikely to reproduce the specific mutant gene dose that is present in heterozygous mutant cells in FOP patients.

The outreach program has two main components: educating teachers through hands - on training and tours of our zebrafish facility, and bringing the zebrafish to K - 12th grade classrooms for hands - on experiments.

A paper on the work, «Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development,» was published in the journal eLife this week.

«Our research used zebrafish to focus on one aspect of this system — how the enterocyte cells inside our intestines respond to a high - fat meal.»

Because of the usefulness of this information, we set ourselves the goals of constructing a zebrafish gene set based on RNA - Seq alone and then identifying the highest quality models.

A new study published in BMC Evolutionary Biology by the team lead by Xesús Abalo and Dan Larhammar, Department of Neuroscience and SciLifeLab at Uppsala University, sheds light on the evolutionary origin of vertebrate vision and the specialisations in zebrafish to adapt to changing lighting conditions.

Based on this knowledge, Saffitz and his colleagues engineered a new strain of zebrafish.

Laura Paye, Westfield, Massachusetts; University of Maine Honors College; research site: University of Maine; mentor: Rebecca Van Beneden, Ph.D., professor of biochemistry and marine sciences, University of Maine; research topic: The effect of embryonic arsenic exposure on the sensorimotor behavior of zebrafish (Danio rerio).

On display were transparent zebrafish embryos just a few days old.