For patients with partial response to
once daily therapy, tailored therapy with adjustment of dose timing and / or twice daily dosing should be considered in patients with night - time symptoms, variable schedules, and / or sleep disturbance.
Not exact matches
While the
once -
daily dosing, low side - effects profile, and shortened treatment duration of interferon - free direct - acting antivirals are ideal for injection drug users, most trials of these
therapies for HCV have excluded persons with recent injection drug use.
«Beginning with our first anti-HIV drug, Viread, approved in 2001, and with the subsequent launches of Emtriva, Truvada, and most recently Atripla, all of which are dosed
once daily with or without food, Gilead has been front and center in developing
once -
daily combination antiretroviral
therapy,» Bischofberger says.
Ezio Bonifacio, Ph.D., of the DFG Center for Regenerative
Therapies Dresden, Technische Universitat Dresden, Germany and colleagues randomly assigned autoantibody - negative, genetically at - risk children to receive oral insulin at varying doses (n = 15) or placebo (n = 10)
once daily for 3 to 18 months to assess whether oral insulin can induce a potentially protective immune response without causing adverse effects.
Once the diagnosis had been made, the team of neuropsychologists provided a three - week block of
therapy during which the patient undertook
daily training to improve his visual perception of depth.
Patients with higher - risk myelofibrosis (with no exclusions for baseline anaemia or thrombocytopenia) were randomly assigned (2:1) to receive oral pacritinib 400 mg
once daily or best available
therapy (BAT) excluding JAK2 inhibitors until disease progression or unacceptable toxicity.
Though she had been in other recovery programs, Ellen agrees to try
once more and enrolls herself in a program which allows her to her group
therapy twice
daily.
If no improvement is observed after 2 months of
therapy, dosage may be increased to a maximum of 2.0 mg / kg
once daily.