Sentences with phrase «oncogene c»

Kimmel Cancer Center investigators discover relationship between well known oncogene c - myc and a newly discovered enzyme called PRDX3.

This study also found that GATA - 3 regulates the signaling pathway that activates the oncogene c - MYC.

This drug - triggered relationship induces the expression of the oncogene c - Myc, leading to reduced sensitivity to the cancer drug and eventually relapse.

Not exact matches

The microRNA also impeded two other oncogenes, c - Met and HIF2A.

However, on page 1391 in this issue, Yun et al. (5) show that high doses of vitamin C selectively kill colorectal cancer cells carrying activating mutations in the oncogenes KRAS or BRAF, which are often refractory to approved targeted therapies.

In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.

Uenaka A, Ono T, Akisawa T, Wada H, Yasuda T, Nakayama E. Identification of a unique antigen peptide pRL1 on BALB / c RL male 1 leukemia recognized by cytotoxic T lymphocytes and its relation to the Akt oncogene.

An even bigger obstacle is that two of the four factors, c - Myc and Klf4, are oncogenes — they cause cancer.

It has been observed that c 4 (CDK4) gene amplification, is an independent oncogene, and is more common in acral and mucosal melanoma than the CSID and NCSID cutaneous melanomas [20, 47].

34) Lockwood WW †, Chari R, Coe BP, Girard L, MacAulay C, Lam S, Gazdar AF, Minna JD, Lam WL (2008) DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers.

Promoter hypermethylation of tissue specific tumor supressor genes and point mutation in K - ras, c - myc proto - oncogenes in urinary (transitional cell) bladder carcinoma