Sentences with phrase «one by bone»

Precisely what one expects when a daylong snowstorm is followed by a bone - chilling deep freeze.

This dating to before Abraham's time seems to be supported by bone fragments and other archaeological remains.

Even if by some inconceivable chance we were to come upon their traces, can we be sure that we should be able to recognize the first thinking beings, either by their bones or the products of their activity?

Open your mouth To feed that flesh Your teeth have bled Tongue us out Bone by bone Do not allow Man to be fed By bread alone

You can hold the chop by its bone and dip it into the soup if you like.

Russell Moore, chef and owner at Camino restaurant in Oakland, gave us this technique for grilling chicken breast — and it's the juiciest version we've ever had, protected from overcooking by the bones and skin.

I manage a BBQ kitchen and I find that if I smoke chicken and serve it right from the smoke, our customers think it is raw or not done because of the redness or pinkish color, especially by the bone.

Q: Dear Dr. BBQ, I manage a BBQ kitchen and I find that if I smoke chicken and serve it right from the smoke, our customers think it is raw or not done because of the redness or pinkish color, especially by the bone.

To see that he did, Allen prepared for his audition by boning up on an earlier Rose Bowl game that he hadn't seen, and came to the station to deliver a stirring account of how Alabama tied the score against Stanford in the last minutes.

Normally when you step on the ground your feet touching the ground produce vibrations that travel through your legs, and get absorbed by the bones, joints and muscles.

The «tunnel» formed by the bones and ligament in the wrist can become compressed by the swelling and fluid retention common in pregnancy, squeezing a nerve that produces the painful sensations.

The picture was posted by Bone earlier in the week after he caught wind of a Twitter exchange between Marjory Stoneman Douglas student and gun rights advocate Kyle Kashuv and national security lawyer Bradley P. Moss.

The researchers also examined skin slices from two patients with another form of nerve disease called AL amyloidosis, caused by a bone marrow disorder.

The 126 bones of the latter - day leviathan, some laid out on tables, others in drawers, form the centerpiece of an exhibition entitled From the Deep: The Sperm Whale, Bone by Bone.

The sternum's ossification — a process in which the cartilage is replaced by bone — is a prerequisite to withstand the stresses of flight.

Since osseointegration is influenced by bone metabolism, this study investigates the association between SSRIs and the risk of failures in osseointegrated implants.

«About five percent of people have some kind of cartilage tumor in their bones, and in most cases it's because the growth - plate cartilage cells weren't fully replaced by bone tissue,» Alman said.

Compared to the hunter - gatherers who preceded them, the farmers had a nearly 50 per cent increase in enamel defects indicative of malnutrition, a fourfold increase in iron - deficiency anemia (evidenced by a bone condition called porotic hyperostosis), a theefold rise in bone lesions reflecting infectious disease in general, and an increase in degenerative conditions of the spine, probably reflecting a lot of hard physical labor.

Made by bone cells, the FGF23 hormone travels via the bloodstream to cells in all organs, where it regulates many aspects of mineral metabolism.

As the cells mature, they must also be stimulated to move as they would be by bone growth and body movement in a living animal.

Everybody has suPAR, which is produced by bone marrow cells, in their blood, with normal levels around 2400 picogram per milliliter (pg / ml).

In short, researchers will be able to assess bone density loss by measuring energy levels absorbed by bones via the device.

Yanoconodon's stirrup, anvil and hammer bones are still connected to the jaw by another bone — gone from adult modern mammals.

«The ethical problem posed by the bones of this 18th century individual approximates to that of all human remains conserved in public collections, displayed in museums or other cultural institutions,» said Dr. Charlier.

This means that when we swivel our eyeballs sideways, we have a lateral view of the world that is unimpeded by the bones of the skull, unlike other apes.

Produced by our bones, osteocalcin affects how we metabolize sugar and fat.

At the same time, Stiner and her colleagues found, the locals started eating fewer tortoises and mollusks and more hares, as evidenced by the bones found at human settlements.

Thanks to this hormone, produced by bone cells, sugar is metabolized more easily.

The realignment process was driven by bone growth, which acted like a mechanical jack to generate the opposing forces required to straighten the two bone fragments.

These studies revealed that the void's physical characteristics — the type and location of missing bone — were consistent with a fibrous dysplastic neoplasm, a tumor caused by a bone growth disorder, the scientists report online today in PLOS ONE.

The team's findings demonstrate that irisin produced by bone could have a role in bone metabolism through both direct mechanisms and indirect mechanisms, as the transition from white fat to brown fat has been shown to lead to increased bone formation by previous studies.

Now, the Laboratory of Malaria Immunology Team at the Immunology Frontier Research Center (IFReC), Osaka University, headed by Professor Cevayir COBAN, have used mouse malaria models to show that robust immune activation and invasion of parasite by - products into the bone marrow during and after malaria infection leads to an adverse balance in bone homeostasis - a process usually tightly controlled - by bone forming osteoblasts and bone resorbing osteoclasts.

«Further experimentation will be needed to evaluate the involvement of irisin and other factors increased by exercise and expressed by bone, muscle and fat tissue.»

Antibacterial drugs are sometimes prescribed to treat and prevent infection caused by bone marrow suppression, a side effect of cancer drugs.

More than 30 patients have been treated for SCID, and more than 90 percent of those children have been cured of their disorder — an improvement over the 50 percent chance of recovery offered by bone marrow transplants.

Alex Huang and Drew Pardoll, with Elizabeth Jaffee and Hyam Levitsky at Johns Hopkins School of Medicine demonstrate tumor - associated antigen processing and presentation to CD8 + T cell by bone marrow - derived professional antigen presenting cells via «cross-priming.»

The patient was treated on an acute lymphoblastic leukemia (ALL) protocol for eight cycles of hyperCVAD (cyclophosphamide, vincristine, adriamycin and decadron) alternating with MTX / Ara - C (methotrexate and cytarabine) and achieved complete remission (CR) confirmed by a bone marrow biopsy and by the resolution of most of her skin lesions.

Formation of mineralized nodules by bone marrow derived cells in a 2D and 3D matrix.

This new knowledge has paved the way for the therapeutic transfer of stem cells not only for the treatment of hematopoietic diseases by bone marrow transplantation â $» first attempted by E. Donnall Thomas, one of this bookâ $ ™ s editors, in 1957 â $» but also for the treatment of many other disorders.

Our laboratory has studied the role of various proprotein convertases in the degradation and cell biology of FGF - 23, a peptide hormone secreted by bone cells which controls phosphate metabolism via its action in the kidney.

IGF prevents frailty by increasing skeletal muscle mass (sarcopenia), sex drive (infertility), brain thymus (immunosenescence, centenarians maintain a strong immune system), skeletal bone mineralization and marrow stem cell formation (osteoporosis and immune system by bone marrow immune cells working in tandem with thymus and lymphs nodes), I understand that diabetes, an accelerated aging phenotype, is insulin IGF and blood glucose driven.

These factors include chemokine (C - X-C motif) ligand 12 (CXCL12), a chemokine produced by bone marrow mesenchymal cells that functions as a chemoattractant and survival factor for cells bearing the chemokine (C - X-C motif) receptor 4 (CXCR4), and insulin - like growth factor 1 (IGF - 1), a factor that is stored in the bone matrix and released during osteolysis (28).

He showed that SOXC proteins are required to form cartilage growth plates, that is, the specialized type of cartilage that drives skeletal elongation in fetal and postnatal vertebrates and that also initiates the progressive replacement of cartilage by bone.

Immune cells are formed in the bone marrow by bone marrow stem cells.

Both receptors are known to bind and mediate signalling by bone morphogenetic proteins (BMPs), and the related GDFs, which are major subgroups of the TGF - β superfamily [23,28].

Researchers describe a new approach to improve in vivo osteogenesis by bone marrow - derived stem cells and thereby enhance bone defect repair strategies

It is characterized by bone abnormalities, cataracts, and intellectual disability.

Examples are blood cells that must be replaced by the bone marrow every 90 days, the skin cells that slough off as the outer layer to be replaced by new layers of cells underneath.

Sclerostin is a protein produced by bone cells which has a negative impact on the formation of bone when expressed at high levels by decreasing bone formation, and IGF - 1 is a hormone associated with the growth of bone.

It is recommended that women should use natural hormones a minimum of five years but each individual woman may use them as long as they feel the hormones are of benefit to them, their skin texture and bone density (as demonstrated by bone density testing).