Sentences with phrase «only human cell type»

While scientists have successfully reprogrammed different types of mouse cells (fibroblasts, liver and intestinal cells), skin fibroblasts were the only human cell type they had ever tried their hands on.

Not exact matches

«However, because SIF - seq only requires DNA sequence from a mammal and can be used in a variety of cell types, it should be possible to compare the neuronal enhancers present in a large genomic region from human to the neuronal enhancers present in the orthologous chimpanzee region.

Human immunodeficiency virus - type 1 (HIV - 1) replicates actively in infected individuals, yet cells with intracellular depots of viral protein are observed only infrequently.

Through this study there is a prospect of a new type of antibiotics «turning off» the oxygen only to the harmful bacteria cells, not to human cells.

First produced only in the past decade, human induced pluripotent stem cells (iPSCs) are capable of developing into many or even all human cell types.

Most experiments with human stem cells have only shown that the cells can acquire the phenotype of various differentiated cell types, but have not shown that the cells are functional at the transplantation site.

Despite having only six cell types, whereas humans have about 200, and no nervous system, Trichoplax appears to coordinate a complex sequence of behaviors culminating in external digestion of algae.

Not only muscle cells, but also all other cell types continually generate forces in the human body.

In tests using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate neurons and other brain cell types — the scientists found that exposure to sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.

«ViaCyte was the first to differentiate human stem cells into glucose - responsive, insulin - producing cells, and now we are running the first and only clinical trials of stem cell - derived islet replacement therapies for type 1 diabetes,» said Paul Laikind, PhD, President and CEO of ViaCyte.

Keirstead's laboratory was the first in the world to develop a method to restrict human embryonic stem cells so they generate large amounts of only one cell type in high purity.

He added: «Truly naive human ES cell lines would not only help answer fundamental questions about how we are made, and be useful for drug screening and tissue therapy, but they would also provide a benchmark against which other types of stem cells could be measured in terms of their effectiveness in stem cell therapy and regenerative medicine.»

In an effort to solve this problem, a team of scientists from Israel and the United States have created a new type of cell that doesn't exist in nature — human stem cells with only half of our naturally occurring chromosomes.

The study relates to a particular type of vaccine (killed) against a particular virus, influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and human papilloma virus (HPV, the causative agent of cervical cancer).

One reason why we know little about this process of telomerase silencing is because specific telomerase regulation naturally occurs only in human cells but not in mouse cells, a widely used model organism where telomerase is active in all cell types.

Telomere shortening occurs in human cells because the enzyme telomerase that adds DNA to the telomere is only active in few cell types, namely stem cells, and is turned off in most other human cells.

He found that expression was elevated only in beta cells both in humans with type 2 diabetes and in mice that model the disease.

San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering human definitive endoderm cells, an essential cell for generating not only pancreatic type cells, which Novocell is developing for use as a cell therapy for diabetes, but also other endoderm lineage - derived tissues and organs such as lungs, intestine, liver, thymus and thyroid.

But Stephan quickly realized the strategy's limitations: only about two new genes could be introduced into cells, and scientists were limited by the types of molecules that human cells can produce.

Concern about alkylphenols first surfaced decades ago when a group at Tufts observed an excessive proliferation of human breast cancer cells in certain types of plastic containers, something that would normally only be seen if the cells were exposed to some type of estrogen.