Not exact matches
«A study covering a
large number of subjects, like the one in 2015, makes it possible to identify the relevant
genes across the entire population; but their variations have
only a limited impact on individuals.
Neanderthal genetic material is found in
only small amounts in the genomes
of modern humans because, after interbreeding, natural selection removed
large numbers of weakly deleterious Neanderthal
gene variants, according to a study by Ivan Juric and colleagues at the University
of California, Davis, published November 8th, 2016 in PLOS Genetics.
The mice seem to develop normally when
only one copy
of the
gene is removed, but microscopic inspection reveals a
number of small «gaps,» or disorganized regions
of tissue (on the scale
of a few nanometers) on their aortas, the
largest artery in their bodies.
«The sophisticated
gene analysis that led to this finding was
only possible because
of the
large number of ALS samples available,» said ALS Association chief scientist Lucie Bruijn, PhD, in a press release.
Despite the
large number of breeds affected by HC
only a single
gene, the transcription factor HSF4, has been implicated in the development
of cataracts in dogs to date.
In fact, culling
large numbers of dogs from a
gene pool
only serves to further reduce the size
of the
gene pool.