The more it's expressed
only on cancer cells, the more targeted the therapy becomes,» says Colin Weekes, MD, PhD, CU Cancer Center investigator and assistant professor in the Division of Oncology at the CU School of Medicine.
Not exact matches
It's
only been tested
on mice so far, but the results are tremendously promising for an antibody Stanford researchers have been experimenting with that blocks the body from «eating»
cancer cells.
I mean, if god wants him to live he wouldn't have given him
cancer in the first place but lets just say he contr.acted can.cer
on his own but was called upon god to do these good dee.ds but needed more time, now what if the
only way he could survi.ve was from stem
cell res.earch?
Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into m
Only cancer cells that received these growth factors switched
on this pathway, and
only they could seed new tumours when injected into m
only they could seed new tumours when injected into mice.
What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give
cancer cells properties of immune
cells by supplying the surface of the
cancer cell with a receptor that normally
only exists
on the white blood
cells that travel through the lymphatic system.
Future research should not
only compare how embryonic stem
cells, iPS
cells and adult stem
cells differentiate, but focus
on what effects the niche in which these
cells will reside, when transplanted, will have
on their characteristics, including tendencies to mutate into
cancer cells, notes
cell and stem
cell biologist Olga Genbacev at the University of California, San Francisco, (U.C.S.F.) School of Medicine.
At first it was thought that
only functioned as cellular debris warehouses but in recent years has been that could have an important role as a messenger between
cells of the body and now many groups focus their research
on the role that could be played exosomes in various diseases, including
cancer.
In this study, we found that chloroquine not
only has an effect
on the growth of the
cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.
In work published this week in
Cell, Tavazoie and his colleagues describe how fluctuations in the amount of tRNAs can have a dramatic impact not only on the fate of a single cell, but also on diseases like metastatic breast can
Cell, Tavazoie and his colleagues describe how fluctuations in the amount of tRNAs can have a dramatic impact not
only on the fate of a single
cell, but also on diseases like metastatic breast can
cell, but also
on diseases like metastatic breast
cancer.
«We
only need to increase concentration beyond levels found in a healthy diet for an effect
on prostate
cancer cells.»
In a four - year study conducted
on the mouse model in advanced breast
cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not
only killed tumor
cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a
cell line that is extremely difficult to kill.
«These inhibitors not
only target
cancer cells but may also have a negative impact
on the immune system and NK
cells.
«The big surprise,» Discher said, «is that injected macrophages circulate all around the body but accumulate
only within the tumors where they engorge
on cancer cells.»
While transplantation of T
cells alone had
only little impact
on tumor size in cancerous mice, the researchers achieved substantial regression of the
cancer by transplanting both T
cells and activated eosinophils.
With so much work needed in studying the nature of stem
cells and using them to study disease processes, therapies based
on ES
cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering
Cancer Center in New York, who pointed out that so far there have
only been two published papers
on therapeutic cloning, both of them in mice.
To devise a potential new therapy, the investigators engineered a population of neural stem
cells to express a potent version of a gene called TRAIL, which codes for a molecule that activates
cell - death - inducing receptors found
only on the surface of
cancer cells.
By contrast, the neoantigen vaccine is custom - made for each patient using antigens produced by mutations unique to the patient's
cancer and
only present
on cancer cells, thus bypassing the nature immune tolerance process.
It's
only three patients
on a low dose of
cells, but San Diego - based Poseida said the results — activity against the
cancer and no «cytokine storm» side effects that often come with CAR - T therapy — were good enough to step up to the next dose.
A full accounting of what is going
on under the hood still remains to be accomplished, but the most plausible mechanism appears to be increased stem
cell activity, while effects
on cancer may involve a more active immune system - though that is
only speculative theory at this point.
Once taken up by antigen - presenting
cells, which help focus the immune system
on an invader, the vaccine releases a factor that heightens their attention specifically to the
cancer - promoting protein E7, a so - called oncoprotein that not
only enables the human papillomavirus to multiply, but potentially cervical
cancer cells to do the same.
«Not
only does I124 - chlor home in
on cancer cells; it also can deliver physical damage.»
Aptamers targeted mucin - 1 (MUC1), a glycosylated surface protein overexpressed
on many
cancers, including MCF7 breast
cancer cells, and
only minimally expressed in MCF - 10A non-cancerous
cells.
Both reviewers consider that since the functional studies were
only tested in 2 basal and 2 luminal breast
cancer cell lines, the sample set was too small, and testing additional
cell lines for their dependency
on MELK should further strengthen the authors conclusions.
Not
only that consuming sugar won't speed the growth of
cancer cells, but eliminating carbohydrates from your diet will make your whole body starve and suffer — all
cells in your organism depend
on these nutrients for energy.
Agarwal said: «
Cancer cells are fast - growing
cells,» then goes
on to say, «not
only that, but they are necessarily fast growing.
I just read something about how
cancer cells can
only thrive
on glucose, and in its absence we can prevent
cancer potentially.
The proliferation rates of the
cancer in the flax - eaters were
only half that of the controls, confirming the test - tube studies done
on prostate
cancer cells suggesting that flax can indeed slow prostate tumor growth.
What made this study so remarkable, was that not
only did
cancer cells die off in greater abundance when IGF - 1 levels were lowered through diet, but that the
cell death benefits were nulled when the researchers put back the IGF - 1 into the blood and re dripped it
on the
cell line.
Cancer cells can
only survive
on glucose, hence why low - glycemic diets are often recommended.
The theory is that
cancer cells can
only live
on the protein of solid food.
Since these experiments were
only performed
on cancer cells in test tubes, the researchers took the next step and ran tests
on breast
cancer tumors in live mice.
A flaw prevents them from making the switch to using ketone bodies as fuel and thus,
cancer cells can
only stay alive
on glucose.
At diagnosis, inflammatory breast
cancer is either stage III or IV disease, depending
on whether
cancer cells have spread
only to nearby lymph nodes or to other tissues as well.
Cinnamon's effect
on cancer cells and tumor growth has so far
only been studied in animals, but was found to be toxic to
cancer cells and to cause
cancer cell death.
In the multi-media installation «Known / Unknown: Plague Column» at PPOW, Schneemann examines the history of health and illness in a gender context, where permutated
cancer cells metastasize amid a background of religious symbolism; no doubt a comment
on how female diseases like breast
cancer have had received
only lagging attention until recently when, in a bizarre twist, campaigns promoting breast
cancer awareness are now trivialized into marketing tools and even at times overtly sexualized.