The only randomized study of adjuvant chemotherapy in mucosal melanoma demonstrated significantly increased relapse - free and overall survival in patients receiving temozolomide and cisplatin, as compared with interferon alfa - 2b or observation.
Not exact matches
However, numbers were small (for example, there were
only 81 fathers across three
studies in Bakermans - Kranenburg), and
studies such as May et al. did not
randomize.
In the
only controlled,
randomized scientific
study to compare graduated extinction and «positive routines» head - to - head, there were no significant differences in treatment outcomes for kids (Adams and Rickert 1989).
Our
study illustrates that a
randomized intervention trial with good socioeconomic information can help assess interventions designed to improve population health not
only by examining the intervention effects on primary outcomes but also by evaluating the intervention's impact on socioeconomic inequalities.
Most
studies attempt to circumvent this by using
randomized experimentation, usually comparing reactions, preferences with identical fictional candidates, varying
only race / ethnicity / gender.
The
study, called the Bypass Surgery Versus Everolimus - Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST) trial, is one of
only two
randomized controlled trials to compare bypass to angioplasty since the introduction of everolimus - eluting stents, a new generation of drug - eluting stent.
«Not
only do we believe that high - quality,
randomized clinical trials are necessary to determine the safety of the Lariat device for off - label procedures, but our analysis raises broader issues with the FDA 510 (k) clearance protocol for medical devices,» said
study senior author Jay Giri, MD, MPH, assistant professor in the Cardiovascular Medicine Division at Penn. «We believe there needs to be a method for reassessing the safety of a device that has been cleared for one use but is being frequently used for a different purpose in real - world practice.»
The Physicians» Health
Study II (PHS II) remains the
only randomized, large - scale, long - term trial to test whether a daily multivitamin reduced cardiovascular disease risk, and researchers found that after 11 years of follow up, there was no significant difference in risk of major cardiovascular disease (CVD) events among men who took a multivitamin compared to those that took a placebo.
Study authors assigned 75 participants (46 women, 29 men) aged 18 to 30 years to an alcohol -
only or A+ED condition in a double - blind
randomized pre - versus post-test experiment.
This Phase 3
randomized, double - blind
study included 763 adults with chronic HCV genotype 1 infection, a form of the virus found in up to 75 percent of infections, and compensated liver diseases, who had previously not responded or
only partially responded to at least one course of peginterferon and ribavirin.
We
randomized female volunteers who were «non-meditators» — having little to no previous experience with meditation — to either the resort
only (herein referred to as the vacation arm of the
study) or to the retreat (herein referred to as the novice meditation arm) during the same week.
Not
only is vitamin D deficiency a risk factor for osteoporosis, but epidemiological
studies and
randomized, controlled trials suggest a correlation with diseases including cardiovascular disease, some cancers, respiratory infections, and multiple sclerosis.
«We tried to equalize the two groups in terms of other health behaviors, but
only a
randomized trial would offer more definitive information,» White says, referring to a
study in which women would be randomly assigned to receive fish oil or a placebo.
In an Independent Scientific Clinical
Study (a
randomized, comparative, double blind trial conducted October 20 — December 10, 2013), we learned that Renew Pure Radiance Oil not
only delivers amazing results, it also out performs the iconic Crème de La Mer across every test measurement — from wrinkle reduction to increased hydration.
In an Independent Scientific Clinical
Study (a
randomized, comparative, double blind trial conducted October 20 — December 10, 2013), we learned that Renew Pure Radiance Oil & Renew Cellular Repair Serum not
only delivers amazing results, it also out performs the iconic Crème de La Mer across every test measurement — from increased hydration to fine line and wrinkle reduction.
HMB and Vitamin D are the
only supplements reviewed in this paper that have been shown to improve strength and balance in
randomized, placebo - controlled
studies with elderly subjects.
The analysis was based on data from 123 overweight - to - obese, sedentary, Seattle - area women, ages 50 to 75, who were randomly assigned to two arms of a controlled,
randomized year - long dietary weight - loss intervention
study: diet
only and exercise plus diet.
In this
study, instead of giving nursing home residents vitamin D and calcium supplements, they
randomized them to sunlight exposure and calcium supplements, and those that got the calcium pills had significantly increased mortality, lived shorter lives than the sunshine
only group.
So it all seems plausible that whole grain intake does indeed offer direct benefits; however,
only results from
randomized controlled intervention
studies can provide the evidence of cause and effect.
In an Independent Scientific Clinical
Study (a
randomized, comparative, double blind trial conducted October 20 — December 10, 2013), we learned that Renew Pure Radiance Oil not
only delivers amazing results, it also outperforms the iconic Crème de La Mer across every test measurement — from wrinkle reduction to increased hydration.
In a
randomized, crossover
study designed to compare the effects of supplemental pectin (12 g / d), cellulose (15 g / d), and lignin (12 g / d) on stool characteristics of healthy volunteers, cellulose was the
only fiber that significantly decreased (â $ «27 percent) mean stool transit time and increased mean wet stool weight (+57 percent)(Hillman et al., 1983).
Recent
studies of whole - school - reform programs and school management have included
only two
randomized experiments, both on James Comer's School Development Program, which means that the effects of Catholic schools, Henry Levin's Accelerated Schools program, or Total Quality Management have never been investigated using experimental techniques.
The full
study, «A
Randomized Controlled Trial of Professional Development for Interdisciplinary Civic Education,» will be available and free to all on the Teacher's College Record website for one week
only beginning today, April 15.
And its results align almost perfectly with those of the Head Start Impact
Study, the
only other large
randomized trial that examines the longitudinal effects of having attended a public pre-k program.
Though
only one year of data is available for analysis at this point, the
study has involved a
randomized field trial of over 400 teachers and administrators broken into test and control groups.
To date, there has
only been 1 published
randomized study on individual psychoeducation, 4 but group intervention has not been tested.
The BEIP is a longitudinal
study of a sample of children raised from early infancy in institutions in Bucharest, Romania, and the
only randomized controlled trial of foster care as an alternative to institutional rearing for abandoned children (61).
Thus far,
only a few, small, not
randomized, no control group
studies have been published.
Type of
Study:
Randomized controlled trial Number of Participants: 63 Intervention, 49 Methadone -
only
Collaborative care is an empirically supported method of extending the reach, quality, and outcomes of care for common mental disorders in medical settings.6, 7
Randomized trials of collaborative care have demonstrated improved outcomes among patients with depression and anxiety,7 - 9 depression - related suicidal ideation, 10 depression and chronic health conditions (eg, diabetes, asthma), 11 and chronic pain.12, 13 For PTSD, however, we are aware of only 3 published randomized trials, 1 demonstrating improvements in PTSD14 and 2 that do not15, 16 — hence the need for additional study of collaborative care
Randomized trials of collaborative care have demonstrated improved outcomes among patients with depression and anxiety,7 - 9 depression - related suicidal ideation, 10 depression and chronic health conditions (eg, diabetes, asthma), 11 and chronic pain.12, 13 For PTSD, however, we are aware of
only 3 published
randomized trials, 1 demonstrating improvements in PTSD14 and 2 that do not15, 16 — hence the need for additional study of collaborative care
randomized trials, 1 demonstrating improvements in PTSD14 and 2 that do not15, 16 — hence the need for additional
study of collaborative care for PTSD.
A total of 6
studies were described as
randomized; 2
studies used
only pre-post comparisons to analyze data pertaining to the therapeutic relationship.
Of the
studies evaluating the effectiveness of attachment - theory - based intervention programs,
only two have dealt exclusively with maltreated children and parents who had been reported to child protection services.4, 5 These two
studies, noteworthy for their
randomized trial method, found a substantial reduction in disorganized attachment behaviours and an increase in secure attachment behaviours among infants and young children resulting from attachment - theory - based interventions.
We addressed some of the prior criticisms of EBT research by ensuring that (1) participants and
study context were clinically representative, (2) there were no systematic differences in clinician competence across conditions (ie, all clinicians were randomly assigned), and (3) the sample would include the ethnic diversity that critics have found insufficient in the
randomized controlled trial literature.17 - 20 Accordingly, we obtained samples from outpatient treatment programs that served the general public across a broad demographic and income range, we included
only youths whose families sought treatment (ie, no recruiting or advertising), all treatment was provided by professional clinicians employed in the participating programs, and all treatment was provided in those programs (ie, not in university laboratory clinics).
Because the focus of this
study is to understand the factors that influence engagement and retention in an ecodevelopmental, parent - centered preventive intervention,
only those participants
randomized to the experimental condition were included in these analyses.