Khiabanian H, Hirshfield KM, Goldfinger M, Bird S, Stein M, Aisner J, Toppmeyer D, Wong S, Chan N, Dhar K, Gheeya J, Vig H, Hadigol M, Pavlick D, Ansari S, Ali S, Xia B, Rodriguez - Rodriguez L, Ganesan S. Inference of Germline Mutational Status and Evaluation of Loss of Heterozygosity in High - Depth, Tumor -
Only Sequencing Data.
Not exact matches
Under the hood, each
Sequence ledger is an immutable, append -
only data structure.
He argues that whole genomes will not
only provide more
data for building trees, but will also enable researchers to study the evolution of regulatory
sequences, transposable elements, and other aspects of the genome that are not covered with OpenWings
sequencing.
Not
only has the parasitic micro jellyfish evolved a stripped - down body plan of just a few cells, but via
data generated at the KU Medical Center's Genome
Sequencing Facility researchers also found the myxozoan genome was drastically simplified.
A conventional computer processes
data only in
sequence and stores memory in a separate unit.
Genomic - scale amounts of protein - coding
sequence data were not
only insufficient but were also misleading for generating an accurate avian phylogeny due to convergence.
Mnemonics rely not
only on repetition to remember facts, but also on associations between easy - to - remember information and to be remembered lists of
data, based on the principle that the human mind much more easily remembers
data attached to spatial, personal, or otherwise meaningful information than that occurring in meaningless
sequences.
Although the researchers
only sequenced about 2 % of the mother's and fetus's genome, this was enough
data to distinguish levels of chromosome 21 in mothers carrying a Down syndrome baby from those with a normal fetus as early as 14 weeks.
«We're
only going to learn that by generating lots more
sequencing data.»
The complete genome
sequence data from the collected viruses will not
only expand our knowledge of the virulence factors, but provide detailed information on evolution and transmission of RSV strains, host - pathogen interactions, and pathogen - microbiome relationships that occur during viral infection.
Our interest is to not
only generate next - generation
sequence data, but to mine this
sequence data to better understand the evolution, pathogenesis, and transmission of ZIKV following the outbreak in Brazil in 2015.
Please note that the recommendations are based on immunogen
sequence only we currently do not hold any rabbit specific
data.
Extracting proper information from large
data has become not
only a serious problem of Next Generation
Sequencing (NGS), which produces an enormous amount of
data, but also a difficult task for 3D molecular databases, as the amount of such
data is increasing dramatically as well.
Our results suggest that information on the state of the host - parasite relationship in vivo can be provided by measurements of the differential expression of different var groups, and need
only be defined by short stretches of
sequence data.
The LymphoTrack ® product lines, LymphoTrack Dx (CE - IVD) and LymphoTrack (Research Use
Only), build upon the significant advancements made in massively parallel
sequencing using the MiSeq ® and Ion PGM ™ instruments and offer a complete solution: kits include multiplex master mixes with built in adaptors and indices for a one - step PCR to generate
sequence ready amplicons, controls, and complimentary bioinformatics software for easy
data analysis, visualization, and interpretation.
This discriminatory power will
only increase as ambitious large - scale
sequencing projects like CCDG make their
data publicly available.
From the test
sequence data, my colleagues and I knew that the specimens were «complex» enough to obtain the full genome, but the
only way to put the code together would be by using the genome of the band - tailed pigeon as a reference map.
A combination of
sequencing data from two different platforms, as suggested by Nothnagel et al. [5] for the reduction of false positives in newly identified SNVs, is
only of limited use for combining the strengths in coverage of different genomic regions.
Interestingly, the performance of Complete Genomics
sequencing can be enhanced by adding HiSeq2000
data at 15x coverage, which can currently be obtained by
only one lane of HiSeq2000
sequencing (paired t - test on percentage sensitivity comparing Complete Genomics and Complete Genomics + HiSeq2000 15x, p = 0.008692).
Although low, the overlap between our
data set and those previously generated (6.2 %) was quite similar to the overlap between the previously generated
data sets themselves (8.1 %, [28]-RRB-, and may reflect 1) the possibility that
only a limited set of Oct4 targets are in proximity to a PORE
sequence, and 2) potential low genomic coverage in our search.
Similarly, a combination of Complete Genomics
data at full coverage with as little as 15x HiSeq2000
data (typically obtained with
only one
sequencing lane) shows a major increase of covered bases in simple repeats (Figure 4b).
[5] For example, one study used such
data to show that less than half of students assigned to remediation in English and
only a third in math ever completed the course
sequence to which they were assigned.
Locally developed
data suggests
only modest success in continued course
sequence of college level English and Math.
Before that, the
only condition was that «Nature requests authors to deposit
sequence and x-ray crystallography
data in the databases that exist for this purpose.»
The
data indicate that the epigenetic response to maternal care involves not
only single candidate gene promoters but includes transcriptional and intragenic
sequences, as well as those residing distantly from transcription start sites.