Sentences with phrase «only switch genes»

Not exact matches

The only trouble was that the Nasmyth lab was devoted entirely to the study of the HO gene (involved in mating - type switching) in the budding yeast Saccharomyces cerevisiae.

«The IMM teams showed clearly that the gene was switched on only in hypoxic regions,» says Sue Kingsman, the research director of Oxford BioMedica.

This test determined that only a few genes switched off when signaling was blocked — and one of them was the gene known to code for MHCI.

One group showed how enhancers maintain the right level of sensitivity to other signals, so that they switch on genes only at the right times and places.

Dr Kat Arney, science communication manager at Cancer Research UK, said: «Only a tiny fraction of our DNA contains actual genes, and we know that at least some of the bits in between — often dismissed as «junk» — play important roles in controlling how genes get switched on and off at the right time and in the right place.

To do so it has to make special enzymes to eat that sugar and it only makes those enzymes if it is exposed to that sugar — it's a signal in a sense — and what happens is that a protein falls off of those genes and essentially the genes switch on and start making their enzymes.

Seeking fresh sources, they looked for cells that express the gene neurogenin 3, a potential sign of cell differentiation because it is the first gene to only switch on in pancreatic islets during embryonic development.

The trick was to link a gene that tells a cell to commit suicide to a promoter, or genetic «on» switch, that is active only in embryos.

Although the gene for tyrosinase is present in all cells, it is switched on only in melanocytes — by a «switch» gene.

As long as such genes were attached to the switch, they would act only in melanocytes.

Some of these SNPs had previously been associated with different diseases and are located near «imprinted» genes — genes in which only the maternally or paternally inherited copy is «switched - on» to encode a protein.

With the help of this grant, we are generating mice engineered to switch off the APOE gene only in microglia and performing molecular profiling without having to isolate microglial cells first.

Using a combination of stem cells and novel analytical tools, scientists at the Wellcome Sanger Institute and their collaborators discovered that clues to the contribution of genetic variation to disease risk lie not only in the genes, but also in the molecular switches that control those genes.

Well, they're back at it, only this time, they're studying what causes those thousands of genes to switch on and off.

Genes aren't single - function, self - contained switches, and we're only just beginning to learn how they interact — both with other genes and with environmental and lifestyle factors — to create living, unique human beGenes aren't single - function, self - contained switches, and we're only just beginning to learn how they interact — both with other genes and with environmental and lifestyle factors — to create living, unique human begenes and with environmental and lifestyle factors — to create living, unique human beings.

But by placing the gene under the control of a «promoter» — an on - off switch for gene expression — from a gene (SM22a) that is expressed only in smooth muscle cells, Dr. Parmacek's team found that no matter which types of cells were infected, the gene was only «turned on» in smooth muscle cells.

LA JOLLA — The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade.

«Those DNA sequences were put into the mutant; this allows you to test the effect of the gene if it is only switched on in a specific layer.»

Oct - 4 is most consistently expressed of the pluripotency genes that we have studied, and it is switched off only in populations that have lost other measurable features of pluripotency, such as stem cell surface marker expression and the capacity for self - renewal.

The switch keeps the gene on so that the salmon produces growth hormone year round, rather than only during warm weather.

In fact, a single meal or snack of sugar or refined carbohydrate can not only turn off fat - burning and significantly disturb hormones, but also switch on the genes that cause disease.

When you put the clues together, you can see that the drop in carbs can not only fuels the candida / yeast through ketones, but the drop in fermentable fiber switches on the hyphal growth gene in the yeast and candida, causing it to become pathogenic.

Another one of natures super foods, broccoli is not only high in vitamin A but also contains a compound that has the ability to work on a genetic level to «switch off» cancer genes, AND to hinder the progression of cancer.

Though the research is currently limited to animals only, scientists have been able to significantly increase muscle building when muscles have been placed under loaded stretches - presumably by creating additional muscle damage and by stimulating the same gene pathways switched on by the tension of muscle contraction.

Normal male cats only inherit one X chromosome so this is active in all skin cells as there is nothing equivalent on the Y chromosome which could «switch off» the O gene.