Sentences with phrase «only tumour cells»

Not exact matches

The AR - V7 variant is formed when an androgen receptor loses the end part of the receptor, called the C - terminal end; this is deleted due to an error in RNA processing in tumour cells, leaving only the beginning part of the receptor, the N - terminal end.

Only cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into mOnly cancer cells that received these growth factors switched on this pathway, and only they could seed new tumours when injected into monly they could seed new tumours when injected into mice.

«We would hope to create little protein factories in the tumour cell that are only switched on when the cells are hypoxic,» says Kingsman.

Mutations that occur in the first malignant cells, those in the trunk of this evolutionary tree, will end up in all the tumour cells; mutations that arise later will be found only in the tree's branches.

The ideal tool for diagnosis would be a non-invasive blood test; however, currently available tests only identify around three in five malignant germ cell tumours, potentially delaying diagnosis and the ability to prioritise patients for surgery.

Such a drug would block only the androgen receptor in prostate cells, and so stop the chain of reactions leading to further tumour growth, says McCague.

This bank of living tumour cells allowed the team to study not only the genetics of the cells, but also how genetic mutations in the mitochondria — which drive energy production in the cell — caused changes in the cell's metabolism.

First, the researchers inhibited the tumour cell mitochondria, by restricting the cancer cells only to glucose as a fuel source; then, they took away their glucose, effectively starving the cancer cells to death.

There is a danger that the Adriamycin would only get to the cells in the centre of the tumour, and fail to reach cells on the periphery, he believes.

«This important study not only adds more genetic risk factors to the list of those known for testicular germ cell tumours — the most common cancer in young men — but also adds detail to the emerging picture of testicular cancer as a strongly heritable disease.

Their studies have shown that, while progenitor cells can give rise to benign lesions, only stem cells have the capacity to develop into deadly invasive tumours.

There are four different kinds of lumps and only one out of the four — the mast cell tumour — is potentially malignant.